(Q34349864)

English

A novel immunomodulator, FTY-720 reverses existing cardiac hypertrophy and fibrosis from pressure overload by targeting NFAT (nuclear factor of activated T-cells) signaling and periostin

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

A novel immunomodulator, FTY-720 reverses existing cardiac hypertrophy and fibrosis from pressure overload by targeting NFAT (nuclear factor of activated T-cells) signaling and periostin (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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object named as

Liu W

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Europe PubMed Central

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1 August 2017

Sanjoy K. Chowdhury

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object named as

Chowdhury SK

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1 August 2017

7

object named as

Travis M

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1 August 2017

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object named as

Prehar S

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1 August 2017

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object named as

Hanley NA

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1 August 2017

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object named as

Oceandy D

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1 August 2017

17

object named as

Lei M

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1 August 2017

author name string

Min Zi

2

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Europe PubMed Central

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1 August 2017

Hoyee Tsui

3

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Europe PubMed Central

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1 August 2017

Leo Zeef

5

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1 August 2017

Qing-Jun Meng

6

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1 August 2017

Andrew Berry

9

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1 August 2017

Ludwig Neyses

11

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1 August 2017

Rui-Ping Xiao

12

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Europe PubMed Central

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1 August 2017

Yunbo Ke

14

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Europe PubMed Central

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1 August 2017

R John Solaro

15

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Europe PubMed Central

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1 August 2017

Elizabeth J Cartwright

16

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1 August 2017

Xin Wang

18

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1 August 2017

language of work or name

0 references

publication date

10 June 2013

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Europe PubMed Central

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1 August 2017

Circulation: Heart Failure

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

6

1 reference

Europe PubMed Central

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1 August 2017

4

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1 August 2017

833-844

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Europe PubMed Central

PubMed publication ID

1 August 2017

Deletion of periostin reduces muscular dystrophy and fibrosis in mice by modulating the transforming growth factor-β pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Animal models of heart failure: a scientific statement from the American Heart Association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Reverse remodeling in heart failure--mechanisms and therapeutic opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

The progression of hypertensive heart disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Periostin advances atherosclerotic and rheumatic cardiac valve degeneration by inducing angiogenesis and MMP production in humans and rodents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Origin of cardiac fibroblasts and the role of periostin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Role of integrin-mediated TGFbeta activation in the pathogenesis of pulmonary fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Periostin as a heterofunctional regulator of cardiac development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Targeting sphingosine-1-phosphate signalling for cardioprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Genetic manipulation of periostin expression in the heart does not affect myocyte content, cell cycle activity, or cardiac repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Cardiac GPCRs: GPCR signaling in healthy and failing hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

ECM remodeling in hypertensive heart disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

TGFbeta, cardiac fibroblasts, and the fibrotic response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

FTY720: mechanism of action and potential benefit in organ transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Hypertrophy of the heart: a new therapeutic target?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

FTY720: from bench to bedside

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Cardiac hypertrophy: the good, the bad, and the ugly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Cardiac fibrosis as a cause of diastolic dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

G-proteins in growth and apoptosis: lessons from the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

The role of interleukin-6 in the failing heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

TGF-beta signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

6 July 2018

Tissue stiffness, latent TGF-beta1 activation, and mechanical signal transduction: implications for the pathogenesis and treatment of fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

27 October 2018

Selective activation of G alpha i mediated signalling of S1P3 by FTY720-phosphate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

27 October 2018

FTY720, a synthetic sphingosine 1 phosphate analogue, inhibits development of atherosclerosis in low-density lipoprotein receptor-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871200

27 October 2018

FTY720: placebo-controlled study of the effect on cardiac rate and rhythm in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/23753531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

1 reference

https://pubmed.ncbi.nlm.nih.gov/23753531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/CIRCHEARTFAILURE.112.000123

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

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