(Q34352230)

1 August 2017

title

Homocysteine, another risk factor for Alzheimer disease, impairs apolipoprotein E3 function (English)

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1 August 2017

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Hirohisa Minagawa

1

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1 August 2017

Atsushi Watanabe

2

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1 August 2017

Hiroyasu Akatsu

3

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1 August 2017

Kayo Adachi

4

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1 August 2017

Chigumi Ohtsuka

5

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1 August 2017

Yasuo Terayama

6

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1 August 2017

Takashi Hosono

7

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1 August 2017

Satoshi Takahashi

8

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1 August 2017

Hideaki Wakita

9

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1 August 2017

Cha-Gyun Jung

10

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1 August 2017

Hiroto Komano

11

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1 August 2017

Makoto Michikawa

12

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1 August 2017

language of work or name

English

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publication date

1 October 2010

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1 August 2017

number of pages

7

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Journal of Biological Chemistry

inferred from page(s)

published in

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1 August 2017

volume

285

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1 August 2017

issue

49

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1 August 2017

page(s)

38382-38388

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describes a project that uses

1 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2992271/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Apolipoprotein E4 (1-272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992271

Mechanism underlying apolipoprotein E (ApoE) isoform-dependent lipid efflux from neural cells in culture

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992271

Hyperhomocysteinemia increases beta-amyloid by enhancing expression of gamma-secretase and phosphorylation of amyloid precursor protein in rat brain

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992271

ApoE promotes the proteolytic degradation of Abeta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992271

Hyperhomocysteinemia and Alzheimer's disease: A systematic review

6 July 2018

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Novel action of apolipoprotein E (ApoE): ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from neurons

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992271

Apolipoprotein E4 in macrophages enhances atherogenesis in a low density lipoprotein receptor-dependent manner

6 July 2018

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Apolipoprotein E polymorphism, age and coronary heart disease

6 July 2018

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Elevated levels of homocysteine compromise blood-brain barrier integrity in mice

6 July 2018

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Homocysteine and folate as risk factors for dementia and Alzheimer disease

6 July 2018

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Apolipoprotein E4 domain interaction occurs in living neuronal cells as determined by fluorescence resonance energy transfer

6 July 2018

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Molecular interactions between apoE and ABCA1: impact on apoE lipidation

6 July 2018

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Isoform-dependent cholesterol efflux from macrophages by apolipoprotein E is modulated by cell surface proteoglycans.

6 July 2018

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Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice

6 July 2018

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Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

6 July 2018

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Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons

6 July 2018

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Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways

6 July 2018

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APOE genotype as a risk factor for ischemic cerebrovascular disease: a meta-analysis

6 July 2018

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Homocysteine and risk of stroke.

6 July 2018

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6 July 2018

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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

6 July 2018

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6 July 2018

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Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice

6 July 2018

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apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110.146258

Hyperhomocysteinemia as an independent risk factor for silent brain infarction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110.146258

Plasma homocysteine levels and risk of Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110.146258

Increase of total homocysteine concentration in cerebrospinal fluid in patients with Alzheimer's disease and Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110.146258

Hyperhomocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid beta peptide levels

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110.146258

In vitro and in vivo interactions of homocysteine with human plasma transthyretin.

21 January 2018

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S-Homocysteinylation of transthyretin is detected in plasma and serum of humans with different types of hyperhomocysteinemia

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110.146258

Homocysteine induces cell death of rat astrocytes in vitro

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110.146258

Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.

21 January 2018

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A novel action of alzheimer's amyloid beta-protein (Abeta): oligomeric Abeta promotes lipid release.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992271

Altered cholesterol metabolism in human apolipoprotein E4 knock-in mice

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20889503

12 December 2020

inferred from PubMed ID database lookup

Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20889503

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M110.146258

1 reference

1 August 2017

1 reference

1 August 2017

1 reference