(Q34353586)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

CRISPR-mediated direct mutation of cancer genes in the mouse liver (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Tuomas Tammela

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Nikhil S. Joshi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

14

Tyler Jacks

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

author name string

Sidi Chen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Hao Yin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Thales Papagiannakopoulos

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Wenxin Cai

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Gillian Yang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Roderick Bronson

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Denise G Crowley

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Feng Zhang

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Daniel G Anderson

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Phillip A Sharp

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

language of work or name

English

0 references

publication date

6 August 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

volume

514

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

issue

7522

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

page(s)

380-384

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

Global microRNA depletion suppresses tumor angiogenesis.

12 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

CRISPR-Cas systems for editing, regulating and targeting genomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Stable RNA interference rules for silencing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Correction of a genetic disease in mouse via use of CRISPR-Cas9.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Repurposing CRISPR/Cas9 for in situ functional assays.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Cas9 as a versatile tool for engineering biology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

DNA targeting specificity of RNA-guided Cas9 nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

RNA-guided human genome engineering via Cas9

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Multiplex genome engineering using CRISPR/Cas systems

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

The functions and regulation of the PTEN tumour suppressor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Stage-specific sensitivity to p53 restoration during lung cancer progression.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Distinct pathways of genomic progression to benign and malignant tumors of the liver.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

WNT and beta-catenin signalling: diseases and therapies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Cancer modeling in the modern era: progress and challenges

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199937

Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems.

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13589

Heritable gene targeting in the mouse and rat using a CRISPR-Cas system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13589

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13589

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13589

Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13589

Exome sequencing of liver fluke-associated cholangiocarcinoma

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25119044

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE13589

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

25119044

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25119044%20AND%20SRC:MED&resulttype=core&format=json