(Q34355626)

1 August 2017

title

Homologous recombination is a primary pathway to repair DNA double-strand breaks generated during DNA rereplication (English)

1 reference

1 August 2017

Lan N Truong

1

1 reference

1 August 2017

Yongjiang Li

2

1 reference

1 August 2017

Emily Sun

3

1 reference

1 August 2017

Katrina Ang

4

1 reference

1 August 2017

Patty Yi-Hwa Hwang

5

1 reference

1 August 2017

Xiaohua Wu

6

1 reference

1 August 2017

language of work or name

English

0 references

publication date

26 August 2014

1 reference

Journal of Biological Chemistry

1 August 2017

published in

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1 August 2017

volume

289

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1 August 2017

issue

42

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1 August 2017

page(s)

28910-28923

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describes a project that uses

1 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4200250/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Deregulated origin licensing leads to chromosomal breaks by rereplication of a gapped DNA template

1 reference

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Repair of strand breaks by homologous recombination

6 July 2018

1 reference

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Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells

6 July 2018

1 reference

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The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks

6 July 2018

1 reference

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Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2

6 July 2018

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The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

6 July 2018

1 reference

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Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

6 July 2018

1 reference

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MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings

6 July 2018

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Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair

6 July 2018

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Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.

6 July 2018

1 reference

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Mechanisms to control rereplication and implications for cancer

6 July 2018

1 reference

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The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted.

6 July 2018

1 reference

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Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior

6 July 2018

1 reference

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Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Strength in numbers: preventing rereplication via multiple mechanisms in eukaryotic cells

6 July 2018

1 reference

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Deregulation of Cdt1 induces chromosomal damage without rereplication and leads to chromosomal instability.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

An ATR- and BRCA1-mediated Fanconi anemia pathway is required for activating the G2/M checkpoint and DNA damage repair upon rereplication

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation

6 July 2018

1 reference

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Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Disruption of mechanisms that prevent rereplication triggers a DNA damage response

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

DNA ligase III as a candidate component of backup pathways of nonhomologous end joining

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional contro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

SV40 T antigen interacts with Nbs1 to disrupt DNA replication control.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Loss of Geminin induces rereplication in the presence of functional p53

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Active Localization of the Retinoblastoma Protein in Chromatin and Its Response to S Phase DNA Damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Pathways of DNA double-strand break repair during the mammalian cell cycle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

A p53-dependent checkpoint pathway prevents rereplication

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

DNA replication: building the perfect switch

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Brca1 controls homology-directed DNA repair

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Genetic dissection of a mammalian replicator in the human beta-globin locus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Site-specific in situ amplification of the integrated polyomavirus genome: a case for a context-specific over-replication model of gene amplification

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Once and only once upon a time: specifying and regulating origins of DNA replication in eukaryotic cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Construction and analysis of simian virus 40 origins defective in tumor antigen binding and DNA replication

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Simian virus 40 T antigen is required for viral excision from chromosomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Simian virus 40 deoxyribonucleic acid synthesis: the viral replicon

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

The T-antigen-binding domain of the simian virus 40 core origin of replication

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Initiation of eukaryotic DNA replication in vitro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Animal virus DNA replication

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Binding and unwinding--how T antigen engages the SV40 origin of DNA replication

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

The in vitro replication of DNA containing the SV40 origin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Simian virus 40 (SV40) large T antigen-dependent amplification of an Epstein-Barr virus-SV40 hybrid shuttle vector integrated into the human HeLa cell genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200250

Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision.

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.576488

Integration and excision of SV40 DNA from the chromosome of a transformed cell

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.576488

Unbalanced expression of licensing DNA replication factors occurs in a subset of mantle cell lymphomas with genomic instability

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.576488

21 January 2018

Identifiers

DOI

10.1074/JBC.M114.576488

1 reference

1 August 2017

1 reference

1 August 2017

1 reference