(Q34359302)

1 August 2017

title

Highly conserved tyrosine stabilizes the active state of rhodopsin (English)

1 reference

1 August 2017

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Joseph A Goncalves

1

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1 August 2017

Kieron South

2

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1 August 2017

Shivani Ahuja

3

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1 August 2017

Ekaterina Zaitseva

4

1 reference

1 August 2017

Chikwado A Opefi

5

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1 August 2017

Markus Eilers

6

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1 August 2017

Reiner Vogel

7

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1 August 2017

Philip J Reeves

8

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1 August 2017

Steven O Smith

9

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1 August 2017

language of work or name

English

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publication date

1 November 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

volume

107

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1 August 2017

issue

46

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1 August 2017

page(s)

19861-19866

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Structure and activation of the visual pigment rhodopsin

1 August 2017

cites work

1 reference

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Identification of two distinct inactive conformations of the beta2-adrenergic receptor reconciles structural and biochemical observations

6 July 2018

1 reference

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Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Location of the retinal chromophore in the activated state of rhodopsin*.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

6 July 2018

1 reference

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Crystal structure of opsin in its G-protein-interacting conformation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Structure of a beta1-adrenergic G-protein-coupled receptor

6 July 2018

1 reference

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Crystal structure of the ligand-free G-protein-coupled receptor opsin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Sequence of late molecular events in the activation of rhodopsin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

6 July 2018

1 reference

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Role of group-conserved residues in the helical core of beta2-adrenergic receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Crystal structure of a photoactivated deprotonated intermediate of rhodopsin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Charged residues of the conserved DRY triplet of the vasopressin V1a receptor provide molecular determinants for cell surface delivery and internalization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Changes in interhelical hydrogen bonding upon rhodopsin activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Structure and orientation of a G protein fragment in the receptor bound state from residual dipolar couplings

6 July 2018

1 reference

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Comparison of helix interactions in membrane and soluble alpha-bundle proteins.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Alanine scanning mutagenesis of CCR3 reveals that the three intracellular loops are essential for functional receptor expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Crystal structure of rhodopsin: implications for vision and beyond

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Crystal structure of rhodopsin: A G protein-coupled receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Light-activated rhodopsin induces structural binding motif in G protein alpha subunit

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Single amino acid residue as a functional determinant of rod and cone visual pigments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Structure and function in rhodopsin: replacement by alanine of cysteine residues 110 and 187, components of a conserved disulfide bond in rhodopsin, affects the light-activated metarhodopsin II state

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Effects of detergents and high pressures upon the metarhodopsin I.dbr.metarhodopsin II equilibrium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Mechanism of activation and inactivation of opsin: role of Glu113 and Lys296

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993422

Conformations of the active and inactive states of opsin

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1009405107

Altered functionality in rhodopsin point mutants associated with retinitis pigmentosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1009405107

Role of the retinal hydrogen bond network in rhodopsin Schiff base stability and hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1009405107

Functional role of the "ionic lock"--an interhelical hydrogen-bond network in family A heptahelical receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1009405107

Constitutive activation of opsin by mutation of methionine 257 on transmembrane helix 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1009405107

Functional Microdomains in G-protein-coupled Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1009405107

Structure and function in rhodopsin. Measurement of the rate of metarhodopsin II decay by fluorescence spectroscopy

21 January 2018

1 reference

12 December 2020

The beta-adrenergic receptor is a substrate for the insulin receptor tyrosine kinase

1 reference

12 December 2020

Opsin/all-trans-retinal complex activates transducin by different mechanisms than photolyzed rhodopsin

1 reference

12 December 2020

Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

1 reference

12 December 2020

Arginine activity in the proton-motive photocycle of bacteriorhodopsin: solid-state NMR studies of the wild-type and D85N proteins

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1009405107

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference