(Q34359769)

1 August 2017

title

DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors (English)

1 reference

1 August 2017

1 reference

Krisztina Arató

2

0 references

Xavier Altafaj

Xavier Altafaj

José M Fernández-Fernández

9

0 references

José M Fernández-Fernández

3

0 references

Susana de la Luna

Susana de la Luna

8

0 references

Isidro Ferrer

7

Isidre Ferrer

1 reference

1 August 2017

Cristina Grau

1

1 reference

1 August 2017

Aitana Valderrama

4

1 reference

1 August 2017

Carlos Sindreu

5

1 reference

1 August 2017

Cristina Fillat

6

1 reference

1 August 2017

publication date

17 October 2014

1 reference

Frontiers in Cellular Neuroscience

1 August 2017

published in

1 reference

1 August 2017

volume

8

1 reference

1 August 2017

page(s)

331

1 reference

Activity-dependent facilitation of Synaptojanin and synaptic vesicle recycling by the Minibrain kinase

1 August 2017

cites work

1 reference

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New Perspectives of Dyrk1A Role in Neurogenesis and Neuropathologic Features of Down Syndrome

6 July 2018

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Phosphorylation of Ser1166 on GluN2B by PKA is critical to synaptic NMDA receptor function and Ca2+ signaling in spines

6 July 2018

1 reference

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Intracellular distribution of differentially phosphorylated dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A).

6 July 2018

1 reference

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NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

6 July 2018

1 reference

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Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome.

6 July 2018

1 reference

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Tyrosine phosphorylation regulates the endocytosis and surface expression of GluN3A-containing NMDA receptors

6 July 2018

1 reference

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Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome.

6 July 2018

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Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior

6 July 2018

1 reference

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Phosphorylation by Dyrk1A of clathrin coated vesicle-associated proteins: identification of the substrate proteins and the effects of phosphorylation

6 July 2018

1 reference

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Diversity in NMDA receptor composition: many regulators, many consequences

6 July 2018

1 reference

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Synaptic plasticity of NMDA receptors: mechanisms and functional implications.

6 July 2018

1 reference

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Exaggerated NMDA mediated LTD in a mouse model of Down syndrome and pharmacological rescuing by memantine

6 July 2018

1 reference

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Molecular determinants controlling NMDA receptor synaptic incorporation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Overexpression of Dyrk1A causes the defects in synaptic vesicle endocytosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Casein kinase 2 regulates the NR2 subunit composition of synaptic NMDA receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Glutamate receptor ion channels: structure, regulation, and function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Molecular responses of the Ts65Dn and Ts1Cje mouse models of Down syndrome to MK-801.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Targeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Sprouty2-mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Evolution of NMDA receptor cytoplasmic interaction domains: implications for organisation of synaptic signalling complexes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Cdk5 regulates the phosphorylation of tyrosine 1472 NR2B and the surface expression of NMDA receptors.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Regulation of NMDA receptors by phosphorylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

PSD-95 and PKC converge in regulating NMDA receptor trafficking and gating

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Trisomy-driven overexpression of DYRK1A kinase in the brain of subjects with Down syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Mouse models of cognitive disorders in trisomy 21: a review

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

The synaptic localization of NR2B-containing NMDA receptors is controlled by interactions with PDZ proteins and AP-2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Regulation of the NMDA receptor complex and trafficking by activity-dependent phosphorylation of the NR2B subunit PDZ ligand

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Src kinases: a hub for NMDA receptor regulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Subunit-specific NMDA receptor trafficking to synapses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Regulation of NMDA receptors by cyclin-dependent kinase-5

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Protein kinase C activation modulates alpha-calmodulin kinase II binding to NR2A subunit of N-methyl-D-aspartate receptor complex.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Characterization of Fyn-mediated tyrosine phosphorylation sites on GluR epsilon 2 (NR2B) subunit of the N-methyl-D-aspartate receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Identification of a phosphorylation site for calcium/calmodulindependent protein kinase II in the NR2B subunit of the N-methyl-D-aspartate receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Synaptic NMDA receptor channels have a low open probability.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

High probability opening of NMDA receptor channels by L-glutamate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

MNB/DYRK1A phosphorylation regulates the interactions of synaptojanin 1 with endocytic accessory proteins

6 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Object recognition memory is conserved in Ts1Cje, a mouse model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

PKC site mutations reveal differential modulation by insulin of NMDA receptors containing NR2A or NR2B subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Subunit-specific regulation of NMDA receptor endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Endocytosis and degradative sorting of NMDA receptors by conserved membrane-proximal signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Specificity determinants of substrate recognition by the protein kinase DYRK1A

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25368549

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FNCEL.2014.00331

1 reference

1 August 2017

1 reference

1 August 2017

1 reference