(Q34360366)

English

Treatment with the Bcl-xL inhibitor ABT-737 in combination with interferon α specifically targets JAK2V617F-positive polycythemia vera hematopoietic progenitor cells

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 August 2017

Treatment with the Bcl-xL inhibitor ABT-737 in combination with interferon α specifically targets JAK2V617F-positive polycythemia vera hematopoietic progenitor cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

polycythemia vera

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based on heuristic

inferred from title

John Mascarenhas

6

object named as

John Mascarenhas

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Europe PubMed Central

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1 August 2017

author name string

Min Lu

1

1 reference

Europe PubMed Central

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1 August 2017

Jiapeng Wang

2

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Europe PubMed Central

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1 August 2017

Yan Li

3

1 reference

Europe PubMed Central

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1 August 2017

Dmitriy Berenzon

4

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Europe PubMed Central

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1 August 2017

Xiaoli Wang

5

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Europe PubMed Central

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1 August 2017

Mingjiang Xu

7

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Europe PubMed Central

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1 August 2017

Ronald Hoffman

8

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1 August 2017

language of work or name

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publication date

12 July 2010

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Europe PubMed Central

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1 August 2017

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Europe PubMed Central

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1 August 2017

116

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1 August 2017

20

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Europe PubMed Central

PubMed publication ID

1 August 2017

4284-4287

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Interferon-alpha targets JAK2V617F-positive hematopoietic progenitor cells and acts through the p38 MAPK pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993627

6 July 2018

Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993627

6 July 2018

Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993627

6 July 2018

Interferon-alpha therapy in bcr-abl-negative myeloproliferative neoplasms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993627

6 July 2018

Pivotal contributions of megakaryocytes to the biology of idiopathic myelofibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993627

6 July 2018

High molecular response rate of polycythemia vera patients treated with pegylated interferon alpha-2a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993627

6 July 2018

JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993627

6 July 2018

Expression of Bcl-x in erythroid precursors from patients with polycythemia vera

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993627

6 July 2018

Activity of the BH3 mimetic ABT-737 on polycythemia vera erythroid precursor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993627

27 October 2018

Involvement of various hematopoietic-cell lineages by the JAK2V617F mutation in polycythemia vera.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993627

27 October 2018

Discrimination of polycythemias and thrombocytoses by novel, simple, accurate clonality assays and comparison with PRV-1 expression and BFU-E response to erythropoietin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993627

27 October 2018

Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993627

9 December 2018

Cytogenetic conversion in a case of polycythaemia vera treated with interferon-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/20625010

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polycythemia vera treated with recombinant interferon-alpha 2a: evidence of a selective effect on the malignant clone

1 reference

https://pubmed.ncbi.nlm.nih.gov/20625010

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive activation of STAT5 and Bcl-xL overexpression can induce endogenous erythroid colony formation in human primary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20625010

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term effects of the treatment of polycythemia vera with recombinant interferon-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/20625010

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recurrence of clonal hematopoiesis after discontinuing pegylated recombinant interferon-alpha 2a in a patient with polycythemia vera

1 reference

https://pubmed.ncbi.nlm.nih.gov/20625010

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-alpha-induced morphological changes of megakaryocytes: a histomorphometrical study on bone marrow biopsies in chronic myeloproliferative disorders with excessive thrombocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20625010

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2010-04-279125

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

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