(Q34360980)

1 August 2017

Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies (English)

1 reference

genome-wide association study

1 August 2017

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3

Marie-France Hivert

1 reference

1 August 2017

M Geoffrey Hayes

1

0 references

Margrit Urbanek

object named as

Margrit Urbanek

2

0 references

Nancy J Cox

23

object named as

Nancy J Cox

1 reference

1 August 2017

11

Caitlin P McHugh

1 reference

1 August 2017

16

Daniel Mirel

1 reference

1 August 2017

Loren L Armstrong

4

1 reference

1 August 2017

Jean Morrison

5

1 reference

1 August 2017

Cong Guo

6

1 reference

1 August 2017

Lynn P Lowe

7

1 reference

1 August 2017

Douglas A Scheftner

8

1 reference

1 August 2017

Anna Pluzhnikov

9

1 reference

1 August 2017

David M Levine

10

1 reference

1 August 2017

Christine M Ackerman

12

1 reference

1 August 2017

Luigi Bouchard

13

1 reference

1 August 2017

Diane Brisson

14

1 reference

1 August 2017

Brian T Layden

15

1 reference

1 August 2017

Kimberly F Doheny

17

1 reference

1 August 2017

Marysa V Leya

18

1 reference

1 August 2017

Rachel N Lown-Hecht

19

1 reference

1 August 2017

Alan R Dyer

20

1 reference

1 August 2017

Boyd E Metzger

21

1 reference

1 August 2017

Timothy E Reddy

22

1 reference

1 August 2017

William L Lowe

24

1 reference

1 August 2017

HAPO Study Cooperative Research Group

25

1 reference

1 August 2017

language of work or name

English

0 references

publication date

31 July 2013

1 reference

1 August 2017

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1 August 2017

62

1 reference

1 August 2017

3282-3291

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1 August 2017

9

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

1 August 2017

start time

30 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Meta-analysis of the relationship between common type 2 diabetes risk gene variants with gestational diabetes mellitus

1 reference

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Architecture of the human regulatory network derived from ENCODE data

6 July 2018

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Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

6 July 2018

1 reference

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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

6 July 2018

1 reference

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Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

A genome-wide association study of gestational diabetes mellitus in Korean women

6 July 2018

1 reference

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The effect of PCSK1 variants on waist, waist-hip ratio and glucose metabolism is modified by sex and glucose tolerance status

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

The proprotein convertases, 20 years later

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Melatonin receptor 1 B polymorphisms associated with the risk of gestational diabetes mellitus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

BACE2 plays a role in the insulin receptor trafficking in pancreatic ß-cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

6 July 2018

1 reference

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Quality control and quality assurance in genotypic data for genome-wide association studies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Biological, clinical and population relevance of 95 loci for blood lipids

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study: common genetic variants in GCK and TCF7L2 are associated with fasting and postchallenge glucose levels in pregnancy and with the new consensus definition of gestational diabetes mellitus from

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

METAL: fast and efficient meta-analysis of genomewide association scans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Association of obesity risk SNPs in PCSK1 with insulin sensitivity and proinsulin conversion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Gestational diabetes: risk factors and recent advances in its genetics and treatment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Molecular evolution of the vertebrate hexokinase gene family: Identification of a conserved fifth vertebrate hexokinase gene.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Variants in MTNR1B influence fasting glucose levels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Glucokinase and molecular aspects of liver glycogen metabolism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Hyperglycemia and adverse pregnancy outcomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Long-term outcomes in mothers diagnosed with gestational diabetes mellitus and their offspring

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Metabolic changes in pregnancy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

A second generation human haplotype map of over 3.1 million SNPs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

A new multipoint method for genome-wide association studies by imputation of genotypes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Childhood obesity and metabolic imprinting: the ongoing effects of maternal hyperglycemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Principal components analysis corrects for stratification in genome-wide association studies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Expression analysis of BACE2 in brain and peripheral tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Long-term effects of the intrauterine environment, birth weight, and breast-feeding in Pima Indians.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Gestational glucose tolerance and risk of type 2 diabetes in young Pima Indian offspring

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

The Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Impaired glucose tolerance in adolescent offspring of diabetic mothers. Relationship to fetal hyperinsulinism.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

Common nonsynonymous variants in PCSK1 confer risk of obesity

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749326

9 December 2018

Identifiers

DOI

10.2337/DB12-1692

1 reference

1 August 2017

1 reference

1 August 2017

1 reference