(Q34365378)

1 August 2017

title

Active ras triggers death in glioblastoma cells through hyperstimulation of macropinocytosis (English)

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1 August 2017

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Jean H Overmeyer

1

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1 August 2017

Aparna Kaul

series ordinal

2

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1 August 2017

Erin E Johnson

series ordinal

3

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1 August 2017

William A Maltese

series ordinal

4

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1 August 2017

publication date

1 June 2008

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Molecular Cancer Research

1 August 2017

published in

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1 August 2017

volume

6

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1 August 2017

issue

6

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1 August 2017

page(s)

965-977

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Role of autophagy in cancer

1 August 2017

cites work

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Activated Ras induces cytoplasmic vacuolation and non-apoptotic death in glioblastoma cells via novel effector pathways

6 July 2018

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Ca2+ and synaptotagmin VII-dependent delivery of lysosomal membrane to nascent phagosomes

6 July 2018

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Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy

6 July 2018

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Gene silencing reveals a specific function of hVps34 phosphatidylinositol 3-kinase in late versus early endosomes

6 July 2018

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6 July 2018

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Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking

6 July 2018

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6 July 2018

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6 July 2018

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Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors.

6 July 2018

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Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis

6 July 2018

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Death by design: apoptosis, necrosis and autophagy

6 July 2018

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The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms

6 July 2018

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Apoptosis, autophagy, and more

6 July 2018

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

6 July 2018

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6 July 2018

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An alternative form of paraptosis-like cell death, triggered by TAJ/TROY and enhanced by PDCD5 overexpression

6 July 2018

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Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

6 July 2018

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The dark side of Ras: regulation of apoptosis

6 July 2018

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Kahalalide F, a new marine-derived compound, induces oncosis in human prostate and breast cancer cells.

6 July 2018

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Is the long‐term survival of patients with intracranial glioblastoma multiforme overstated?

6 July 2018

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Molecular response of human glioblastoma multiforme cells to ionizing radiation: cell cycle arrest, modulation of the expression of cyclin-dependent kinase inhibitors, and autophagy

6 July 2018

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Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

6 July 2018

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Death by necrosis. Uncontrollable catastrophe, or is there order behind the chaos?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Programmed cell death (PCD). Apoptosis, autophagic PCD, or others?

6 July 2018

1 reference

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An alternative, nonapoptotic form of programmed cell death

6 July 2018

1 reference

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

6 July 2018

1 reference

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Regulation of macropinocytosis by p21-activated kinase-1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Survival rates in patients with primary malignant brain tumors stratified by patient age and tumor histological type: an analysis based on Surveillance, Epidemiology, and End Results (SEER) data, 1973-1991.

6 July 2018

1 reference

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The pathways of cell death: oncosis, apoptosis, and necrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Apoptosis, oncosis, and necrosis. An overview of cell death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

A rapid and simple method for the isolation of apoptotic DNA fragments.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Lysosomal proton pump activity: supravital cell staining with acridine orange differentiates leukocyte subpopulations.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

A Detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Studies on the mechanisms of autophagy: formation of the autophagic vacuole

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Studies on the mechanisms of autophagy: maturation of the autophagic vacuole

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

The glycotope-specific RAV12 monoclonal antibody induces oncosis in vitro and has antitumor activity against gastrointestinal adenocarcinoma tumor xenografts in vivo.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Cell death: programmed, apoptosis, necrosis, or other?

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Amiloride kills malignant glioma cells independent of its inhibition of the sodium-hydrogen exchanger

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Induction of autophagic cell death in malignant glioma cells by arsenic trioxide.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Characterization of the necrotic cleavage of poly(ADP-ribose) polymerase (PARP-1): implication of lysosomal proteases

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Increasing complexity of Ras signaling.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994605

Anticancer drug resistance in primary human brain tumors

27 October 2018

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12 December 2020

1 reference

12 December 2020

Lysosome associated membrane protein 1 (Lamp1) traffics directly from the TGN to early endosomes

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12 December 2020

Shikonin circumvents cancer drug resistance by induction of a necroptotic death

1 reference

12 December 2020

Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins

1 reference

12 December 2020

10.1158/1541-7786.MCR-07-2036

Identifiers

DOI

1 reference

release_yfqhs4cnnna7jhnb6vvnvmhoiy

1 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yfqhs4cnnna7jhnb6vvnvmhoiy

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2994605

1 reference

1 August 2017

1 reference