(Q34369834)

1 August 2017

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title

Ceramide in apoptosis signaling: relationship with oxidative stress (English)

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1 August 2017

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Andrieu-Abadie N

1

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1 August 2017

Gouazé V

series ordinal

2

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1 August 2017

Salvayre R

series ordinal

3

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1 August 2017

Levade T

series ordinal

4

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1 August 2017

publication date

1 September 2001

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Free Radical Biology and Medicine

1 August 2017

published in

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1 August 2017

volume

31

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1 August 2017

issue

6

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1 August 2017

page(s)

717-728

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An update of the enzymology and regulation of sphingomyelin metabolism

1 August 2017

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7 January 2021

The role of sphingolipids in the process of signal transduction

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7 January 2021

Regulation of ceramide production and apoptosis

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7 January 2021

Zn2+-stimulated sphingomyelinase is secreted by many cell types and is a product of the acid sphingomyelinase gene

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7 January 2021

Signalling sphingomyelinases: which, where, how and why?

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7 January 2021

Ceramide in the eukaryotic stress response

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7 January 2021

Expression of neutral sphingomyelinase identifies a distinct pool of sphingomyelin involved in apoptosis.

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7 January 2021

prICE: a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2.

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7 January 2021

Cytokine response modifier A (CrmA) inhibits ceramide formation in response to tumor necrosis factor (TNF)-alpha: CrmA and Bcl-2 target distinct components in the apoptotic pathway

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7 January 2021

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

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7 January 2021

TNF receptor death domain-associated proteins TRADD and FADD signal activation of acid sphingomyelinase

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7 January 2021

CD40 signals apoptosis through FAN-regulated activation of the sphingomyelin-ceramide pathway.

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7 January 2021

Distinct sites of action of Bcl-2 and Bcl-xL in the ceramide pathway of apoptosis.

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7 January 2021

Ceramide formation leads to caspase-3 activation during hypoxic PC12 cell death. Inhibitory effects of Bcl-2 on ceramide formation and caspase-3 activation

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7 January 2021

The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis

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7 January 2021

Mitochondria, oxygen free radicals, disease and ageing

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7 January 2021

Hydroperoxide metabolism in mammalian organs

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7 January 2021

Enzymic mechanisms of superoxide production

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7 January 2021

Reactive oxygen species in cell signaling

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7 January 2021

Oxidative stress as a mediator of apoptosis

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7 January 2021

Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis

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7 January 2021

Reactive oxygen species and programmed cell death

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7 January 2021

Thioredoxin peroxidase is a novel inhibitor of apoptosis with a mechanism distinct from that of Bcl-2

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7 January 2021

Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death

1 reference

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7 January 2021

Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Autocrine production of extracellular catalase prevents apoptosis of the human CEM T-cell line in serum-free medium

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Mitochondrial phospholipid hydroperoxide glutathione peroxidase suppresses apoptosis mediated by a mitochondrial death pathway

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

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7 January 2021

The baculovirus antiapoptotic p35 gene also functions via an oxidant-dependent pathway

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7 January 2021

Rapid and specific efflux of reduced glutathione during apoptosis induced by anti-Fas/APO-1 antibody

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Niemann-Pick human lymphoblasts are resistant to phthalocyanine 4-photodynamic therapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)- retinamide in neuroblastoma cell lines

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

UVA radiation stimulates ceramide production: relationship to oxidative stress and potential role in ERK, JNK, and p38 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Involvement of the acid sphingomyelinase pathway in uva-induced apoptosis

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Non-enzymatic triggering of the ceramide signalling cascade by solar UVA radiation

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7 January 2021

Free radicals in biology: oxidative stress and the effects of ionizing radiation

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7 January 2021

Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione

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7 January 2021

Role of plasma membrane coenzyme Q on the regulation of apoptosis

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7 January 2021

Ceramide generation in nitric oxide-induced apoptosis. Activation of magnesium-dependent neutral sphingomyelinase via caspase-3.

1 reference

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7 January 2021

Inhibition of neutral sphingomyelinase activation and ceramide formation by glutathione in hypoxic PC12 cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Ceramide path in human lung cell death

1 reference

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7 January 2021

Coenzyme Q protects cells against serum withdrawal-induced apoptosis by inhibition of ceramide release and caspase-3 activation

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Rapid activation of neutral sphingomyelinase by hypoxia-reoxygenation of cardiac myocytes

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7 January 2021

Nitric oxide donors induce stress signaling via ceramide formation in rat renal mesangial cells

1 reference

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7 January 2021

Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis

1 reference

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7 January 2021

Mitochondrial free radical generation, oxidative stress, and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Ceramide induces hepatocyte cell death through disruption of mitochondrial function in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Mitochondria and cells produce reactive oxygen species in virtual anaerobiosis: relevance to ceramide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Effects of adriamycin on respiratory chain activities in mitochondria from rat liver, rat heart and bovine heart. Evidence for a preferential inhibition of complex III and IV.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Effects of tamoxifen on the electron transport chain of isolated rat liver mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Ceramide Induces CytochromecRelease from Isolated Mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

The biochemistry of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Mitochondrial free radical signal in ceramide-dependent apoptosis: a putative mechanism for neuronal death in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Ceramide Interaction with the Respiratory Chain of Heart Mitochondria†

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Partial purification and characterization of sphingosine N-acyltransferase (ceramide synthase) from bovine liver mitochondrion-rich fraction

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Occurrence of ceramides and neutral glycolipids with unusual long-chain base composition in purified rat liver mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Nitric oxide stimulates chronic ceramide formation in glomerular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

The p75(NTR)-induced apoptotic program develops through a ceramide-caspase pathway negatively regulated by nitric oxide.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Nitric oxide inhibits the tumor necrosis factor alpha -regulated endocytosis of human dendritic cells in a cyclic GMP-dependent way.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Divergence in regulation of nitric-oxide synthase and its cofactor tetrahydrobiopterin by tumor necrosis factor-alpha. Ceramide potentiates nitric oxide synthesis without affecting GTP cyclohydrolase I activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Ceramide-mediated stimulation of inducible nitric oxide synthase (iNOS) and tumor necrosis factor (TNF) accumulation in murine macrophages requires tyrosine kinase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Reactive oxygen species enhances the induction of inducible nitric oxide synthase by sphingomyelinase in RAW264.7 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Glutathione and its role in cellular functions

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Oxalate-induced ceramide accumulation in Madin-Darby canine kidney and LLC-PK1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Redox-sensitive events in Fas-induced apoptosis in human NK cells include ceramide generation and protein tyrosine dephosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Human placenta sphingomyelinase, an exogenous acidic pH-optimum sphingomyelinase, induces oxidative stress, glutathione depletion, and apoptosis in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

The role of ascorbate in antioxidant protection of biomembranes: interaction with vitamin E and coenzyme Q.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Plasma membrane ubiquinone controls ceramide production and prevents cell death induced by serum withdrawal

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

TNF-alpha and IL-1alpha induce apoptosis in subconfluent rat mesangial cells. Evidence for the involvement of hydrogen peroxide and lipid peroxidation as second messengers.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Induction of the manganese superoxide dismutase gene by sphingomyelinase and ceramide

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Direct interaction of GD3 ganglioside with mitochondria generates reactive oxygen species followed by mitochondrial permeability transition, cytochrome c release, and caspase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Acidic sphingomyelinase (ASM) is necessary for fas-induced GD3 ganglioside accumulation and efficient apoptosis of lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Redox-regulated signaling by lactosylceramide in the proliferation of human aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Lactosylceramide stimulates human neutrophils to upregulate Mac-1, adhere to endothelium, and generate reactive oxygen metabolites in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Bcl-2 and mitochondrial oxygen radicals. New approaches with reactive oxygen species-sensitive probes.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Oxidative stress induced by ascorbate causes neuronal damage in an in vitro system.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Apoptosis and activation of the sphingomyelin-ceramide pathway induced by oxidized low density lipoproteins are not causally related in ECV-304 endothelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Oxidized low density lipoprotein induces apoptosis in cultured human umbilical vein endothelial cells by common and unique mechanisms

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Ceramide induces aSMase expression: implications for oxLDL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Lethal forebrain ischemia stimulates sphingomyelin hydrolysis and ceramide generation in the gerbil hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Role of enhanced ceramide generation in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Protective roles for ATM in cellular response to oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Effect of ceramide on intracellular glutathione determines apoptotic or necrotic cell death of JB6 tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

Modulation of ceramide-induced NF-kappaB binding activity and apoptotic response by caffeic acid in U937 cells: comparison with other antioxidants.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900655-4

7 January 2021

10.1016/S0891-5849(01)00655-4

Identifiers

DOI

1 reference

1 August 2017

1 reference