(Q34375884)

1 August 2017

1 reference

title

Murine models for Down syndrome (English)

1 reference

Xavier Estivill i Pallejà

1 August 2017

1 reference

6

1 reference

1 August 2017

María Lourdes Arbonés

object named as

Arbonés M

4

0 references

author name string

Dierssen M

1

1 reference

1 August 2017

Fillat C

2

1 reference

1 August 2017

Crnic L

3

1 reference

1 August 2017

Flórez J

5

1 reference

1 August 2017

language of work or name

English

0 references

publication date

1 August 2001

1 reference

1 August 2017

Physiology & Behavior

1 reference

1 August 2017

73

1 reference

1 August 2017

5

1 reference

1 August 2017

859-871

1 reference

Discovery and genetic localization of Down syndrome cerebellar phenotypes using the Ts65Dn mouse.

1 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superox

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Motor dysfunction in a mouse model for Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Behavioral assessment of the Ts65Dn mouse, a model for Down syndrome: altered behavior in the elevated plus maze and open field

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

A proposed test battery and constellations of specific behavioral paradigms to investigate the behavioral phenotypes of transgenic and knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Alterations of central noradrenergic transmission in Ts65Dn mouse, a model for Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Impaired cyclic AMP production in the hippocampus of a Down syndrome murine model.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Mild impairment of learning and memory in mice overexpressing the mSim2 gene located on chromosome 16: an animal model of Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

A behavioral assessment of Ts65Dn mice: a putative Down syndrome model.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Impaired short- and long-term memory in Ts65Dn mice, a model for Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Reversible impairment of long-term potentiation in transgenic Cu/Zn-SOD mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Autosomal aneuploidy in mice: generation and developmental consequences

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Female specific hyperactivity in S100 beta transgenic mice does not habituate in open-field.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Spatial and nonspatial learning in mice: effects of S100 beta overexpression and age.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Intraneuronal Abeta42 accumulation in human brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Mutant CuZn superoxide dismutase in motor neuron disease

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

The DNA sequence of human chromosome 21

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Consequences of trisomy 16 for mouse brain development: corticogenesis in a model of Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Role of founder cell deficit and delayed neuronogenesis in microencephaly of the trisomy 16 mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Transchromosomal mouse embryonic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Analysis of mammalian central nervous system gene expression and function using bacterial artificial chromosome-mediated transgenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Engineering chromosomes in mice through targeted meiotic recombination (TAMERE)

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Specificity determinants of substrate recognition by the protein kinase DYRK1A

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Hippocampal volume and neuronal number in Ts65Dn mice: a murine model of Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Specific impairment of cardiogenesis in mouse ES cells containing a human chromosome 21.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

[Minibrain/DYRK1A gene: candidate gene for mental retardation in Down's syndrome?]

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Animal models in the study of the biological function of genes on human chromosome 21 and their role in the pathophysiology of Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Synaptic deficit in the temporal cortex of partial trisomy 16 (Ts65Dn) mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Altered metabolism of familial Alzheimer's disease-linked amyloid precursor protein variants in yeast artificial chromosome transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

A murine model for Down syndrome shows reduced responsiveness to pain.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Aggressive behaviour in transgenic mice expressing APP is alleviated by serotonergic drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Twofold overexpression of human beta-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Application of antisense DNA method for the study of molecular bases of brain function and behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

High-level expression of the Mnb/Dyrk1A gene in brain and heart during rat early development.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

The neurobiologic consequences of autosomal trisomy in mice and men.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Altered brain glucose metabolism in transgenic-PFKL mice with elevated L-phosphofructokinase: in vivo NMR studies.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Medial prefrontal cortical injections of c-fos antisense oligonucleotides transiently lower c-Fos protein and mimic amphetamine withdrawal behaviours.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Astrocytosis and axonal proliferation in the hippocampus of S100b transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

A mouse model for Down syndrome exhibits learning and behaviour deficits.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Parallels of craniofacial maldevelopment in Down syndrome and Ts65Dn mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Effects of over- and under-expression of Cu,Zn-superoxide dismutase on the toxicity of glutamate analogs in transgenic mouse striatum.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the beta-amyloid protein precursor of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Construction of a panel of transgenic mice containing a contiguous 2-Mb set of YAC/P1 clones from human chromosome 21q22.2.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

A new aspartyl protease on 21q22.3, BACE2, is highly similar to Alzheimer's amyloid precursor protein beta-secretase

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

The amyloid precursor protein of Alzheimer's disease and the Abeta peptide.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Down's syndrome-like skeletal abnormalities in Ets2 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Functional expression and germline transmission of a human chromosome fragment in chimaeric mice

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Transgenic mice overexpressing the neurotrophic factor S-100 beta show neuronal cytoskeletal and behavioral signs of altered aging processes: implications for Alzheimer's disease and Down's syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Effects of NMDA-R1 antisense oligodeoxynucleotide administration: behavioral and radioligand binding studies.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

Overexpression of liver-type phosphofructokinase (PFKL) in transgenic-PFKL mice: implication for gene dosage in trisomy 21

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900523-6

7 January 2021

10.1016/S0031-9384(01)00523-6

Identifiers

DOI

1 reference

1 August 2017

1 reference