(Q34377698)

1 August 2017

The epidemiology of ALS: a conspiracy of genes, environment and time (English)

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amyotrophic lateral sclerosis

1 August 2017

1 reference

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2

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1 August 2017

Ammar Al-Chalabi

1

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language of work or name

English

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publication date

15 October 2013

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1 August 2017

Nature Reviews Neurology

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1 August 2017

9

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1 August 2017

617-628

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1 August 2017

11

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https://scigraph.springernature.com/pub.10.1038/nrneurol.2013.203

1 August 2017

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cites work

Epidemiologic investigations of amyotrophic lateral sclerosis. 2. Familial aggregations indicative of dominant inheritance. I.

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https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Epidemiologic investigations of amyotrophic lateral sclerosis. 2. Familial aggregations indicative of dominant inheritance. II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

The relationship between abnormalities of cognitive function and cerebral activation in amyotrophic lateral sclerosis. A neuropsychological and positron emission tomography study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Changes in cognition and behaviour in amyotrophic lateral sclerosis: nature of impairment and implications for assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

The ALS/PDC syndrome of Guam and the cycad hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Clinical genetics of amyotrophic lateral sclerosis: what do we really know?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

ALSoD: A user-friendly online bioinformatics tool for amyotrophic lateral sclerosis genetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

A proposed staging system for amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Population based epidemiology of amyotrophic lateral sclerosis using capture-recapture methodology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Riluzole and prognostic factors in amyotrophic lateral sclerosis long-term and short-term survival: a population-based study of 1149 cases in Taiwan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Prognostic factors in ALS: A critical review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Amyotrophic lateral sclerosis in South-East England: a population-based study. The South-East England register for amyotrophic lateral sclerosis (SEALS Registry).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Natural history and clinical features of the flail arm and flail leg ALS variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Study of 962 patients indicates progressive muscular atrophy is a form of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

A long-term prospective study of the natural course of sporadic adult-onset lower motor neuron syndromes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Latent cluster analysis of ALS phenotypes identifies prognostically differing groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Cognitive changes predict functional decline in ALS: a population-based longitudinal study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

The risk to relatives of patients with sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Modelling the effects of penetrance and family size on rates of sporadic and familial disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

An estimate of amyotrophic lateral sclerosis heritability using twin data.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Epidemiology of ALS in Italy: a 10-year prospective population-based study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

The epidemiology of motor neuron disease in Northern Ireland using capture-recapture methodology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Utility of capture-recapture methodology to assess completeness of amyotrophic lateral sclerosis case ascertainment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

The sex ratio in amyotrophic lateral sclerosis: A population based study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Amyotrophic lateral sclerosis in an urban setting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Incidence of amyotrophic lateral sclerosis among American Indians and Alaska natives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Analysis of the C9orf72 hexanucleotide repeat expansion in Korean patients with familial and sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Japanese amyotrophic lateral sclerosis patients with GGGGCC hexanucleotide repeat expansion in C9ORF72.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

A hexanucleotide repeat expansion in C9ORF72 causes familial and sporadic ALS in Taiwan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Prognosis of ALS: comparing data from the Limousin referral centre, France, and a Uruguayan population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Increase in motor neuron disease mortality in Spain: temporal and geographical analysis (1990-2005).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Amyotrophic lateral sclerosis/motor neuron disease deaths in the United States, 1999-2009.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Reduced frequency of ALS in an ethnically mixed population: a population-based mortality study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

An epidemiological study of motor neuron disease in Hong Kong.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Ethnic variation in the incidence of ALS: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Amyotrophic lateral sclerosis on Guam

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Beyond Guam: the cyanobacteria/BMAA hypothesis of the cause of ALS and other neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

C9ORF72 repeat expansion in amyotrophic lateral sclerosis in the Kii peninsula of Japan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Incidence of amyotrophic lateral sclerosis in Europe

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Clinical characteristics and survival pattern of 1,153 patients with amyotrophic lateral sclerosis: experience over 30 years from India.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Lou Gehrig, rawhide, and 1938.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Premorbid weight, body mass, and varsity athletics in ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Validation of the historical adulthood physical activity questionnaire (HAPAQ) against objective measurements of physical activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Lifetime physical activity and the risk of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Amyotrophic lateral sclerosis (ALS): a phylogenetic disease of the corticomotoneuron?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Concordance between site of onset and limb dominance in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Beneficial vascular risk profile is associated with amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Prediagnostic body fat and risk of death from amyotrophic lateral sclerosis: the EPIC cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Premorbid body mass index and risk of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

The sinister side of Italian soccer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Severely increased risk of amyotrophic lateral sclerosis among Italian professional football players

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Sports and trauma in amyotrophic lateral sclerosis revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Three soccer playing friends with simultaneous amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Smoking may be considered an established risk factor for sporadic ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Association of smoking with amyotrophic lateral sclerosis risk and survival in men and women: a prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Smoking and risk of amyotrophic lateral sclerosis: a pooled analysis of 5 prospective cohorts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Exposure to chemicals and metals and risk of amyotrophic lateral sclerosis: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

What we truly know about occupation as a risk factor for ALS: A critical and systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Estimating the occurrence of amyotrophic lateral sclerosis among Gulf War (1990-1991) veterans using capture-recapture methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Occurrence of amyotrophic lateral sclerosis among Gulf War veterans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Neurological mortality among U.S. veterans of the Persian Gulf War: 13-year follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Prospective study of military service and mortality from ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Electrical injury and amyotrophic lateral sclerosis: a systematic review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Spatial clustering of amyotrophic lateral sclerosis in Finland at place of birth and place of death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Differential features of motor neuron disease mortality in Spain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Geographical clustering of amyotrophic lateral sclerosis in South-East England: a population study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Contribution of geolocalisation to neuroepidemiological studies: Incidence of ALS and environmental factors in Limousin, France

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Geographic distribution of amyotrophic lateral sclerosis through motor neuron disease mortality data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Amyotrophic lateral sclerosis in Piedmont (Italy): a Bayesian spatial analysis of the incident cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Temporal trends and geographic clusters of mortality from amyotrophic lateral sclerosis in Japan, 1995-2004.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Biomagnification of cycad neurotoxins in flying foxes: implications for ALS-PDC in Guam

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Biomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Prominent human health impacts from several marine microbes: history, ecology, and public health implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Large proportion of amyotrophic lateral sclerosis cases in Sardinia due to a single founder mutation of the TARDBP gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

How do C9ORF72 repeat expansions cause amyotrophic lateral sclerosis and frontotemporal dementia: can we learn from other noncoding repeat expansion disorders?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Rate of familial amyotrophic lateral sclerosis: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Proposed criteria for familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Analysis of theC9orf72Gene in Patients with Amyotrophic Lateral Sclerosis in Spain and Different Populations Worldwide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Motor neuron disease in the province of Turin, Italy, 1966–1980

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Amyotrophic lateral sclerosis in Sardinia, insular Italy, 1995-2009

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

The natural history of primary lateral sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

An all-Ireland epidemiological study of MND, 2004-2005

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Delineating the genetic heterogeneity of ALS using targeted high-throughput sequencing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Aggregation of neurologic and neuropsychiatric disease in amyotrophic lateral sclerosis kindreds: a population-based case-control cohort study of familial and sporadic amyotrophic lateral sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Neurological picture. Metastatic choriocarcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Smoking, Alcohol Consumption, and the Risk of Amyotrophic Lateral Sclerosis: A Population-based Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Population-based case-control study of amyotrophic lateral sclerosis in western Washington State. I. Cigarette smoking and alcohol consumption

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Prospective study of cigarette smoking and amyotrophic lateral sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

An epidemiologic investigation of amyotrophic lateral sclerosis in Jefferson County, Missouri, 1998-2002

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Age at onset of amyotrophic lateral sclerosis is proportional to life expectancy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2013.203

Low index-to-ring finger length ratio in sporadic ALS supports prenatally defined motor neuronal vulnerability

31 March 2020

1 reference

12 December 2020

Neurologic diseases on the island of Guam

1 reference

12 December 2020

Neurological mortality among Gulf War veterans

1 reference

12 December 2020

[New diagnostic criteria of ALS (Awaji criteria)]

1 reference

12 December 2020

Presumption of service connection for amyotrophic lateral sclerosis. Final rule.

1 reference

12 December 2020

10.1038/NRNEUROL.2013.203

Identifiers

DOI

1 reference

PubMed ID

24126629

Dimensions Publication ID

1 August 2017

0 references

1 reference

PubMed ID

24126629