(Q34381237)

1 August 2017

title

A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity (English)

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1 August 2017

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Shigeyuki Yokoyama

16

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Kohjiro Ueki

13

object named as

Kohjiro Ueki

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1 August 2017

17

Takashi Kadowaki

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1 August 2017

Miki Okada-Iwabu

1

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1 August 2017

Toshimasa Yamauchi

2

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1 August 2017

Masato Iwabu

3

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1 August 2017

Teruki Honma

4

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1 August 2017

Ken-ichi Hamagami

5

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1 August 2017

Koichi Matsuda

6

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1 August 2017

Mamiko Yamaguchi

7

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1 August 2017

Hiroaki Tanabe

8

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1 August 2017

Tomomi Kimura-Someya

9

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1 August 2017

Mikako Shirouzu

10

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1 August 2017

Hitomi Ogata

11

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Kumpei Tokuyama

12

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Tetsuo Nagano

14

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1 August 2017

Akiko Tanaka

15

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1 August 2017

language of work or name

English

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publication date

30 October 2013

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1 August 2017

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1 August 2017

volume

503

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1 August 2017

issue

7477

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1 August 2017

page(s)

493-499

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https://scigraph.springernature.com/pub.10.1038/nature12656

1 August 2017

exact match

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cites work

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12 December 2020

Geldanamycin derivative ameliorates high fat diet-induced renal failure in diabetes

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Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

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Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis

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Mechanisms of disease: using genetically altered mice to study concepts of type 2 diabetes

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Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma

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G-protein-coupled receptors: molecular mechanisms involved in receptor activation and selectivity of G-protein recognition

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Roles of PPARs in health and disease.

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Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle

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Inflammation, stress, and diabetes

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12 December 2020

Adiponectin levels and risk of type 2 diabetes: a systematic review and meta-analysis

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12 December 2020

Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.

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12 December 2020

Macrophages, inflammation, and insulin resistance

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12 December 2020

Biochemistry and molecular cell biology of diabetic complications

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12 December 2020

Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity

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12 December 2020

Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.

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12 December 2020

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

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12 December 2020

Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

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5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase

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12 December 2020

AMPK, the metabolic syndrome and cancer

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12 December 2020

Adenosine 5'-monophosphate-activated protein kinase regulation of fatty acid oxidation in skeletal muscle

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cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1).

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The role of exercise and PGC1alpha in inflammation and chronic disease

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12 December 2020

Plasma adiponectin levels and risk of myocardial infarction in men.

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Obesity is associated with macrophage accumulation in adipose tissue

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Developmental origin of fat: tracking obesity to its source.

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AMPK and the biochemistry of exercise: implications for human health and disease

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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

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A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes

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AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

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The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

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12 December 2020

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

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12 December 2020

Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation

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12 December 2020

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

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12 December 2020

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

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12 December 2020

Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

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12 December 2020

AdipoQ is a novel adipose-specific gene dysregulated in obesity

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12 December 2020

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

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12 December 2020

Calcium ion in skeletal muscle: its crucial role for muscle function, plasticity, and disease

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12 December 2020

Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase

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Cellular mechanisms of insulin resistance

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12 December 2020

The association of changes in physical-activity level and other lifestyle characteristics with mortality among men

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12 December 2020

Identifiers

DOI

10.1038/NATURE12656

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1 August 2017

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