(Q34381321)

1 August 2017

title

Nonlinear pharmacokinetics of piperacillin in healthy volunteers--implications for optimal dosage regimens (English)

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1 August 2017

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Jürgen B Bulitta

1

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Ulrike Holzgrabe

object named as

Ulrike Holzgrabe

4

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author name string

Martina Kinzig

2

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1 August 2017

Verena Jakob

3

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1 August 2017

Fritz Sörgel

5

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1 August 2017

Nicholas H G Holford

6

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1 August 2017

language of work or name

English

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publication date

1 November 2010

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British Journal of Clinical Pharmacology

1 August 2017

published in

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1 August 2017

volume

70

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1 August 2017

issue

5

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1 August 2017

page(s)

682-693

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Inoculum effects of ceftobiprole, daptomycin, linezolid, and vancomycin with Staphylococcus aureus and Streptococcus pneumoniae at inocula of 10(5) and 10(7) CFU injected into opposite thighs of neutropenic mice

1 August 2017

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Continuous infusion of beta-lactams.

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6 July 2018

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Systematic comparison of the population pharmacokinetics and pharmacodynamics of piperacillin in cystic fibrosis patients and healthy volunteers

6 July 2018

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6 July 2018

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6 July 2018

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BACTERIOSTATIC AND LYTIC ACTIONS OF PENICILLIN ON SENSITIVE AND RESISTANT STAPHYLOCOCCI.

6 July 2018

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6 July 2018

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Pharmacodynamic profiling of piperacillin in the presence of tazobactam in patients through the use of population pharmacokinetic models and Monte Carlo simulation

6 July 2018

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6 July 2018

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The effect of the size of the inoculum and the age of the infection on the curative dose of penicillin in experimental infections with streptococci, pneumococci, and Treponema pallidum

6 July 2018

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6 July 2018

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Comparison of the pharmacodynamics of meropenem in healthy volunteers following administration by intermittent infusion or bolus injection.

6 July 2018

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Population pharmacokinetic analysis of nonlinear behavior of piperacillin during intermittent or continuous infusion in patients with cystic fibrosis.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Continuous infusion versus intermittent administration of meropenem in critically ill patients

6 July 2018

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6 July 2018

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Pharmacokinetics and pharmacodynamics of two multiple-dose piperacillin-tazobactam regimens

6 July 2018

1 reference

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6 July 2018

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Is continuous infusion of beta-lactam antibiotics worthwhile?--efficacy and pharmacokinetic considerations

6 July 2018

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6 July 2018

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6 July 2018

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Serum bactericidal activity of ceftazidime: continuous infusion versus intermittent injections.

6 July 2018

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6 July 2018

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6 July 2018

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Comparison of the pharmacokinetic and pharmacodynamic activity of piperacillin and mezlocillin.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Pharmacokinetics of piperacillin in subjects with various degrees of renal function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997308

Comparative antibiotic dose-effect relations at several dosing intervals in murine pneumonitis and thigh-infection models

6 July 2018

1 reference

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Comparative dose-effect relations at several dosing intervals for beta-lactam, aminoglycoside and quinolone antibiotics against gram-negative bacilli in murine thigh-infection and pneumonitis models.

6 July 2018

1 reference

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Pharmacokinetics of ceftazidime in serum and suction blister fluid during continuous and intermittent infusions in healthy volunteers

6 July 2018

1 reference

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Pharmacokinetics and tissue penetration of tazobactam administered alone and with piperacillin

6 July 2018

1 reference

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Continuous infusion of beta-lactam antibiotics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997308

Piperacillin: human pharmacokinetics after intravenous and intramuscular administration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997308

Pharmacokinetics of piperacillin following intravenous administration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997308

6 July 2018

Piperacillin kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997308

Piperacillin penetration into tissue of critically ill patients with sepsis--bolus versus continuous administration?

6 July 2018

1 reference

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Optimal dosing of piperacillin-tazobactam for the treatment of Pseudomonas aeruginosa infections: prolonged or continuous infusion?

27 October 2018

1 reference

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Population pharmacokinetics and pharmacodynamics of piperacillin/tazobactam in patients with complicated intra-abdominal infection

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997308

Pharmacokinetic properties and stability of continuous-infusion meropenem in adults with cystic fibrosis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997308

Use of Monte Carlo Simulation to Design an Optimized Pharmacodynamic Dosing Strategy for Meropenem

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997308

Use of the t > MIC to choose between different dosing regimens of beta-lactam antibiotics

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997308

Antimicrobial Resistance: Pharmacokinetics‐Pharmacodynamics of Antimicrobial Therapy: It’s Not Just for Mice Anymore

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997308

Pharmacokinetics of meropenem in serum and suction blister fluid during continuous and intermittent infusion

9 December 2018

1 reference

12 December 2020

Implications of intraindividual variability in bioavailability studies of furosemide

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12 December 2020

Pharmacokinetic characteristics of piperacillin/tazobactam

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12 December 2020

Penicillin-binding protein expression at different growth stages determines penicillin efficacy in vitro and in vivo: an explanation for the inoculum effect

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12 December 2020

Clinical pharmacokinetics of antimicrobial drugs in cystic fibrosis

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12 December 2020

Prevention of resistance: a goal for dose selection for antimicrobial agents

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12 December 2020

Continuous infusion of beta-lactam antibiotics

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12 December 2020

Piperacillin-tazobactam for Pseudomonas aeruginosa infection: clinical implications of an extended-infusion dosing strategy

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12 December 2020

Target concentration intervention: beyond Y2K

1 reference

12 December 2020

Serum bactericidal activity of ceftazidime administered as continuous infusion of 3 g over 24 h versus intermittent bolus infusion of 2 g against Pseudomonas aeruginosa in healthy volunteers

1 reference

12 December 2020

Dose Dependence of Piperacillin Pharmacokinetics

1 reference

12 December 2020

Continuous infusion ceftazidime in intensive care: a randomized controlled trial

1 reference

12 December 2020

The effect of piperacillin dose on elimination kinetics in renal impairment

1 reference

12 December 2020

Single-dose pharmacokinetics of piperacillin and tazobactam in patients with renal disease

1 reference

12 December 2020

10.1111/J.1365-2125.2010.03750.X

Identifiers

DOI

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1 August 2017

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1 August 2017

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