(Q34388355)

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Identification of benzodiazepine Ro5-3335 as an inhibitor of CBF leukemia through quantitative high throughput screen against RUNX1-CBFβ interaction

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 August 2017

Identification of benzodiazepine Ro5-3335 as an inhibitor of CBF leukemia through quantitative high throughput screen against RUNX1-CBFβ interaction (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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ChEBI release 2020-05-28

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inferred from title

4

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1 August 2017

16

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1 August 2017

William Reinhold

object named as

William C Reinhold

8

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13

object named as

Yves Pommier

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Europe PubMed Central

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1 August 2017

Christopher P Austin

14

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Christopher P Austin

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Europe PubMed Central

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1 August 2017

Juan Jose Marugan

5

object named as

Juan Marugan

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Europe PubMed Central

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1 August 2017

1

object named as

Lea Cunningham

1 reference

Europe PubMed Central

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1 August 2017

17

object named as

Paul Liu

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Europe PubMed Central

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1 August 2017

15

object named as

Kuan-Teh Jeang

1 reference

Europe PubMed Central

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1 August 2017

Venkat S R K Yedavalli

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object named as

Venkat R K Yedavalli

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Europe PubMed Central

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1 August 2017

author name string

Steven Finckbeiner

2

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Europe PubMed Central

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1 August 2017

R Katherine Hyde

3

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Europe PubMed Central

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1 August 2017

Seameen Jean Dehdashti

7

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Europe PubMed Central

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1 August 2017

Lemlem Alemu

9

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Europe PubMed Central

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1 August 2017

Ling Zhao

10

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Europe PubMed Central

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1 August 2017

Jing-Ruey Joanna Yeh

11

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Europe PubMed Central

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1 August 2017

Raman Sood

12

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Europe PubMed Central

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1 August 2017

language of work or name

0 references

publication date

21 August 2012

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Europe PubMed Central

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1 August 2017

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

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1 August 2017

109

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Europe PubMed Central

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1 August 2017

36

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Europe PubMed Central

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1 August 2017

14592-14597

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

T-cell differentiation factor CBF-β regulates HIV-1 Vif-mediated evasion of host restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Matrin 3 is a co-factor for HIV-1 Rev in regulating post-transcriptional viral gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Coordinated regulation of mitochondrial topoisomerase IB with mitochondrial nuclear encoded genes and MYC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Genome-wide mRNA and microRNA profiling of the NCI 60 cell-line screen and comparison of FdUMP[10] with fluorouracil, floxuridine, and topoisomerase 1 poisons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

RUNX1 repression-independent mechanisms of leukemogenesis by fusion genes CBFB-MYH11 and AML1-ETO (RUNX1-RUNX1T1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Accelerated leukemogenesis by truncated CBF beta-SMMHC defective in high-affinity binding with RUNX1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Prognostic impact of specific chromosomal aberrations in a large group of pediatric patients with acute myeloid leukemia treated uniformly according to trial AML-BFM 98.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Exon array analyses across the NCI-60 reveal potential regulation of TOP1 by transcription pausing at guanosine quartets in the first intron

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

HTRF: A technology tailored for drug discovery - a review of theoretical aspects and recent applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

The use of AlphaScreen technology in HTS: current status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Development of multilineage adult hematopoiesis in the zebrafish with a runx1 truncation mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Mouse models of human AML accurately predict chemotherapy response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

CBFbeta is critical for AML1-ETO and TEL-AML1 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Definitive hematopoietic stem/progenitor cells manifest distinct differentiation output in the zebrafish VDA and PBI.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

RUNX genes in development and cancer: regulation of viral gene expression and the discovery of RUNX family genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Prospective analysis of TEL/AML1-positive patients treated on Dana-Farber Cancer Institute Consortium Protocol 95-01.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Analysis of thrombocyte development in CD41-GFP transgenic zebrafish

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Mechanism of leukemogenesis by the inv(16) chimeric gene CBFB/PEBP2B-MHY11.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Core-binding factors in haematopoiesis and leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Oncogenic transcription factors in the human acute leukemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

2-Glycineamide-5-chlorophenyl 2-pyrryl ketone, a non-benzodiazepin Tat antagonist, is effective against acute and chronic HIV-1 infections in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Molecular pathogenesis of the chromosome 16 inversion in the M4Eo subtype of acute myeloid leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

A randomized trial of the activity and safety of Ro 24-7429 (Tat antagonist) versus nucleoside for human immunodeficiency virus infection. The AIDS Clinical Trials Group 213 Team

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Establishment and characterization of a new human leukemia cell line derived from M4E0.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Inhibition of HIV replication in acute and chronic infections in vitro by a Tat antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Restoration of cell surface CD4 expression in human immunodeficiency virus type 1-infected cells by treatment with a Tat antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437880

6 July 2018

Energetic and functional contribution of residues in the core binding factor beta (CBFbeta ) subunit to heterodimerization with CBFalpha.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1200037109

21 January 2018

AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1200037109

21 January 2018

Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1200037109

21 January 2018

The clinical spectrum of adult acute myeloid leukaemia associated with core binding factor translocations

1 reference

https://pubmed.ncbi.nlm.nih.gov/22912405

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22912405

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22912405

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.1200037109

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

2012PNAS..10914592C

0 references

release_vwg7f4qpobesznck2xt5q6ocum

1 reference

https://api.fatcat.wiki/v0/release/vwg7f4qpobesznck2xt5q6ocum

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

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Europe PubMed Central

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1 August 2017

ResearchGate publication ID

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