(Q34389172)

1 August 2017

title

Fragile site orthologs FHIT/FRA3B and Fhit/Fra14A2: evolutionarily conserved but highly recombinogenic (English)

1 reference

1 August 2017

8

Carlo M Croce

1 reference

1 August 2017

Ayumi Matsuyama

1

1 reference

1 August 2017

Takeshi Shiraishi

2

1 reference

1 August 2017

Francesco Trapasso

3

1 reference

1 August 2017

Tamotsu Kuroki

4

1 reference

1 August 2017

Hansjuerg Alder

5

1 reference

1 August 2017

Masaki Mori

6

1 reference

1 August 2017

Kay Huebner

7

1 reference

1 August 2017

language of work or name

English

0 references

publication date

20 November 2003

1 reference

Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

1 reference

1 August 2017

volume

100

1 reference

1 August 2017

issue

25

1 reference

1 August 2017

page(s)

14988-14993

1 reference

ATR Regulates Fragile Site Stability

1 August 2017

cites work

1 reference

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The tumor spectrum in FHIT-deficient mice

6 July 2018

1 reference

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Fragile and unstable chromosomes in cancer: causes and consequences

6 July 2018

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Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

FHIT gene therapy prevents tumor development in Fhit-deficient mice.

6 July 2018

1 reference

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Effect of adenoviral transduction of the fragile histidine triad gene into esophageal cancer cells

6 July 2018

1 reference

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Initial sequencing and analysis of the human genome

6 July 2018

1 reference

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LINE L1 retrotransposable element is targeted during the initial stages of apoptotic DNA fragmentation

6 July 2018

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Characterization of the human TESTIN gene localized in the FRA7G region at 7q31.2

6 July 2018

1 reference

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Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells

6 July 2018

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6 July 2018

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Muir-Torre-like syndrome in Fhit-deficient mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Interspersed repeats and other mementos of transposable elements in mammalian genomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Cancer-specific chromosome alterations in the constitutive fragile region FRA3B.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

The murine Fhit gene is highly similar to its human orthologue and maps to a common fragile site region.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

The murine Fhit locus: isolation, characterization, and expression in normal and tumor cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

FRA10B structure reveals common elements in repeat expansion and chromosomal fragile site genesis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Sequence of the FRA3B common fragile region: implications for the mechanism of FHIT deletion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Replacement of Fhit in cancer cells suppresses tumorigenicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Prediction of complete gene structures in human genomic DNA

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Large-scale comparative sequence analysis of the human and murine Bruton's tyrosine kinase loci reveals conserved regulatory domains

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Mathematical model to predict regions of chromatin attachment to the nuclear matrix

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Human chromosomal fragile site FRA16B is an amplified AT-rich minisatellite repeat

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: direct evidence for the coincidence of viral integration sites and fragile sites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Common regions of deletion in chromosome regions 3p12 and 3p14.2 in primary clear cell renal carcinomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Predicting internal exons by oligonucleotide composition and discriminant analysis of spliceable open reading frames

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Association of a chromosome deletion syndrome with a fragile site within the proto-oncogene CBL2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Constitutive fragile sites and cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Chromosome breakage and recombination at fragile sites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Basic local alignment search tool

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Preferential integration of marker DNA into the chromosomal fragile site at 3p14: an approach to cloning fragile sites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Receptor protein-tyrosine phosphatase gamma is a candidate tumor suppressor gene at human chromosome region 3p21

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Hereditary Renal-Cell Carcinoma Associated with a Chromosomal Translocation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Heritable fragile sites on human chromosomes I. Factors affecting expression in lymphocyte culture

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

FRA3B and other common fragile sites: the weakest links

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2336256100

Regression of upper gastric cancer in mice by FHIT gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2336256100

Evidence that instability within the FRA3B region extends four megabases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2336256100

Positions of chromosome 3p14.2 fragile sites (FRA3B) within the FHIT gene

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299872

Viral integration, fragile sites, and proto-oncogenes in human neoplasia

27 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2336256100

The role of the FHIT/FRA3B locus in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2336256100

Genomic deletions created upon LINE-1 retrotransposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2336256100

Human l1 retrotransposition is associated with genetic instability in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2336256100

Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus vector-mediated fragile histidine triad (FHIT) gene overexpression

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14630947

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.2336256100

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference