(Q34389585)

25220467

1 August 2017

title

P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury (English)

1 reference

25220467

1 August 2017

main subject

traumatic brain injury

0 references

author

Elizabeth A Newell

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Huxing Cui

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Matthew M Harper

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Terry C Yin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Jeremiah K Britt

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Héctor De Jesús-Cortés

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Yuan Lu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Rachel M Genova

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Michael Z Khan

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Jaymie R Voorhees

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Jianqiang Shao

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Aaron C Katzman

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Paula J Huntington

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Cassie Wassink

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Latisha McDaniel

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Laura M Dutca

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Jacinth Naidoo

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Alexander G Bassuk

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Steven L McKnight

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Joseph M Ready

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Andrew A Pieper

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

15 September 2014

1 reference

1 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

1731-1740

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage

1 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis.

6 July 2018

1 reference

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Discovery of a neuroprotective chemical, (S)-N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(-)-P7C3-S243], with improved druglike properties

6 July 2018

1 reference

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P7C3 and an unbiased approach to drug discovery for neurodegenerative diseases

6 July 2018

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Neuroprotective efficacy of a proneurogenic compound after traumatic brain injury

6 July 2018

1 reference

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Double deletion of melanocortin 4 receptors and SAPAP3 corrects compulsive behavior and obesity in mice

6 July 2018

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Retinal ganglion cell damage in an experimental rodent model of blast-mediated traumatic brain injury

6 July 2018

1 reference

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Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease

6 July 2018

1 reference

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Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Neuropathology of explosive blast traumatic brain injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Dementia resulting from traumatic brain injury: what is the pathology?

6 July 2018

1 reference

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Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.

6 July 2018

1 reference

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Assessment of motor balance and coordination in mice using the balance beam

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Mechanisms of primary blast-induced traumatic brain injury: insights from shock-wave research

6 July 2018

1 reference

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Development of proneurogenic, neuroprotective small molecules

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Discovery of a proneurogenic, neuroprotective chemical

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Axon degeneration: Mechanisms and implications of a distinct program from cell death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Neutralization of interleukin-1beta modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Fluorescence imaging of blood-brain barrier disruption

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

The neuronal PAS domain protein 3 transcription factor controls FGF-mediated adult hippocampal neurogenesis in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

A local mechanism mediates NAD-dependent protection of axon degeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Polyglutamine diseases and transport problems: deadly traffic jams on neuronal highways.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Synaptic slaughter in Alzheimer's disease

6 July 2018

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Biosynthesis of diphosphopyridine nucleotide. I. Identification of intermediates.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Axonal self-destruction and neurodegeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Early Neurodegeneration after Hypoxia-Ischemia in Neonatal Rat Is Necrosis while Delayed Neuronal Death Is Apoptosis

6 July 2018

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Quantitative evaluation of vascular permeability in the gerbil brain after transient ischemia using Evans blue fluorescence

6 July 2018

1 reference

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Mild traumatic brain injury in U.S. Soldiers returning from Iraq.

6 July 2018

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Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206693

Absence of Wallerian Degeneration does not Hinder Regeneration in Peripheral Nerve

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25220467

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25220467

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/25220467

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Axon retraction and degeneration in development and disease

1 reference

27 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1146/ANNUREV.NEURO.28.061604.135632

Identifiers

DOI

10.1016/J.CELREP.2014.08.030

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

25220467

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220467%20AND%20SRC:MED&resulttype=core&format=json