(Q21245237)

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Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury

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Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury (English)

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traumatic brain injury

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Daniel Watterson

4

object named as

D Martin Watterson

author given names

D Martin

author last names

Watterson

1 reference

Dimensions Publication ID

18 August 2022

Linda J Van Eldik

3

author given names

Linda J

author last names

Van Eldik

object named as

Linda J Van Eldik

1 reference

Dimensions Publication ID

18 August 2022

author name string

Eric Lloyd

1

author given names

Eric

author last names

Lloyd

1 reference

Dimensions Publication ID

18 August 2022

Kathleen Somera-Molina

2

author given names

Kathleen

author last names

Somera-Molina

1 reference

Dimensions Publication ID

18 August 2022

Mark S Wainwright

5

author given names

Mark S

author last names

Wainwright

1 reference

Dimensions Publication ID

18 August 2022

language of work or name

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publication date

2008

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Journal of Neuroinflammation

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5

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1

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28

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Epilepsy after head injury

1 reference

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19 March 2017

Antiinflammatory action of glucocorticoids--new mechanisms for old drugs

1 reference

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19 March 2017

Neuroprotective agents in traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

19 March 2017

Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study

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7 April 2017

Angiotensin II controls occludin function and is required for blood brain barrier maintenance: relevance to multiple sclerosis

1 reference

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12 September 2017

Glia proinflammatory cytokine upregulation as a therapeutic target for neurodegenerative diseases: function-based and target-based discovery approaches

1 reference

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12 September 2017

Traumatic brain injury: intensive care management

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

12 September 2017

Traumatic brain injury: assessment, resuscitation and early management

1 reference

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12 September 2017

Systemic infections and inflammation affect chronic neurodegeneration

1 reference

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12 September 2017

Neuropharmacological modulation of cognitive deficits after brain damage.

1 reference

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12 September 2017

Cognitive outcome in traumatic brain injury survivors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

12 September 2017

Glia and their cytokines in progression of neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

12 September 2017

Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

12 September 2017

The Janus face of glial-derived S100B: beneficial and detrimental functions in the brain

1 reference

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12 September 2017

Protein kinase involved in lung injury susceptibility: evidence from enzyme isoform genetic knockout and in vivo inhibitor treatment

1 reference

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12 September 2017

Mechanisms involved in the side effects of glucocorticoids

1 reference

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12 September 2017

Inflammatory response in acute traumatic brain injury: a double-edged sword

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

12 September 2017

Chemokines in neurological trauma models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

12 September 2017

Dual role of tumor necrosis factor alpha in brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

12 September 2017

Experimental brain injury induces differential expression of tumor necrosis factor-alpha mRNA in the CNS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

12 September 2017

Epidemiology of head injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

12 September 2017

Inhibition of glial cell activation ameliorates the severity of experimental autoimmune encephalomyelitis.

1 reference

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27 September 2017

A novel p38 alpha MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse model.

1 reference

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27 September 2017

COG1410, a novel apolipoprotein E-based peptide, improves functional recovery in a murine model of traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

27 September 2017

Why have recent trials of neuroprotective agents in head injury failed to show convincing efficacy? A pragmatic analysis and theoretical considerations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

27 September 2017

Monitoring the impact of traumatic brain injury: a review and update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

27 September 2017

Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

27 September 2017

Development of a novel therapeutic suppressor of brain proinflammatory cytokine up-regulation that attenuates synaptic dysfunction and behavioral deficits.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

30 May 2018

Temporal profile of release of interleukin-1beta in neurotrauma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

30 May 2018

Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

30 May 2018

In vivo and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis

1 reference

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30 May 2018

Inhibition of tumor necrosis factor alpha (TNFalpha) activity in rat brain is associated with cerebroprotection after closed head injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

30 May 2018

Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat.

1 reference

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30 May 2018

Inhibitory effect on cerebral inflammatory agents that accompany traumatic brain injury in a rat model: a potential neuroprotective mechanism of recombinant human erythropoietin (rhEPO).

1 reference

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29 November 2018

Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury

1 reference

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29 November 2018

Glial activation links early-life seizures and long-term neurologic dysfunction: evidence using a small molecule inhibitor of proinflammatory cytokine upregulation

1 reference

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29 November 2018

Transient neuroprotection by minocycline following traumatic brain injury is associated with attenuated microglial activation but no changes in cell apoptosis or neutrophil infiltration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

29 November 2018

An apolipoprotein E-based therapeutic improves outcome and reduces Alzheimer's disease pathology following closed head injury: evidence of pharmacogenomic interaction

1 reference

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29 November 2018

Self-reported psychosocial health among adults with traumatic brain injury

1 reference

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29 November 2018

Chronic ibuprofen administration worsens cognitive outcome following traumatic brain injury in rats

1 reference

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29 November 2018

Glia as a therapeutic target: selective suppression of human amyloid-beta-induced upregulation of brain proinflammatory cytokine production attenuates neurodegeneration.

1 reference

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29 November 2018

Neuropsychological sequelae of diffuse traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

29 November 2018

A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

29 November 2018

Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

29 November 2018

Aminopyridazines attenuate hippocampus-dependent behavioral deficits induced by human beta-amyloid in a murine model of neuroinflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

29 November 2018

Improved recovery and delayed cytokine induction after closed head injury in mice with central overexpression of the secreted isoform of the interleukin-1 receptor antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

29 November 2018

Discovery of a 3-amino-6-phenyl-pyridazine derivative as a new synthetic antineuroinflammatory compound

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

29 November 2018

Extracellular superoxide dismutase overexpression improves behavioral outcome from closed head injury in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

29 November 2018

Current recommendations for neurotrauma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

29 November 2018

Traumatic brain injury (TBI) 10-20 years later: a comprehensive outcome study of psychiatric symptomatology, cognitive abilities and psychosocial functioning.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

29 November 2018

Head injury: recent past, present, and future.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

29 November 2018

Selective chemokine mRNA expression following brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

29 November 2018

A new model of diffuse brain injury in rats. Part I: Pathophysiology and biomechanics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

29 November 2018

Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483713

29 November 2018

Apolipoprotein E affects the central nervous system response to injury and the development of cerebral edema

1 reference

https://pubmed.ncbi.nlm.nih.gov/18590543

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MLCK210 gene knockout or kinase inhibition preserves lung function following endotoxin-induced lung injury in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18590543

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The presence of tumour necrosis factor in CSF and plasma after severe head injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/18590543

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/18590543

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 receptor antagonist suppresses neurotrophin response in injured rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/18590543

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 and tumor necrosis factor-alpha synergistically mediate neurotoxicity: involvement of nitric oxide and of N-methyl-D-aspartate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18590543

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incidence of mild and moderate brain injury in the United States, 1991

1 reference

https://pubmed.ncbi.nlm.nih.gov/18590543

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Closed head injury--an inflammatory disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18590543

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1742-2094-5-28

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