(Q34389618)

1 August 2017

title

The soluble guanylate cyclase stimulator riociguat ameliorates pulmonary hypertension induced by hypoxia and SU5416 in rats (English)

1 reference

1 August 2017

0 references

1 reference

ChEBI release 2020-05-28

ChEBI ID

76018

pulmonary hypertension

1 reference

Norbert Weissmann

5

0 references

Ralph T Schermuly

Ralph Theo Schermuly

11

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Friedrich Grimminger

Friedrich Grimminger

6

0 references

Werner Seeger

Werner Seeger

9

0 references

Johannes-Peter Stasch

8

Johannes-Peter Stasch

1 reference

1 August 2017

2

Baktybek Kojonazarov

1 reference

1 August 2017

10

Hossein Ardeschir Ghofrani

1 reference

1 August 2017

1

Michaela Lang

1 reference

1 August 2017

Xia Tian

3

1 reference

1 August 2017

Anuar Kalymbetov

4

1 reference

1 August 2017

Axel Kretschmer

7

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1 August 2017

language of work or name

English

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publication date

17 August 2012

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1 August 2017

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1 August 2017

volume

7

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1 August 2017

issue

8

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1 August 2017

page(s)

e43433

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Creative Commons Attribution 4.0 International

1 August 2017

copyright license

start time

17 August 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Copper dependence of angioproliferation in pulmonary arterial hypertension in rats and humans

1 reference

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Soluble guanylate cyclase stimulation prevents fibrotic tissue remodeling and improves survival in salt-sensitive Dahl rats

6 July 2018

1 reference

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Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension

6 July 2018

1 reference

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Mechanisms of disease: pulmonary arterial hypertension.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension.

6 July 2018

1 reference

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Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure.

6 July 2018

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Cellular and molecular basis of pulmonary arterial hypertension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Discovery of riociguat (BAY 63-2521): a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

NO-independent, haem-dependent soluble guanylate cyclase stimulators

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Sildenafil citrate therapy for pulmonary arterial hypertension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Reversal of experimental pulmonary hypertension by PDGF inhibition

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Nitric oxide pathway and phosphodiesterase inhibitors in pulmonary arterial hypertension.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

The NO - K+ channel axis in pulmonary arterial hypertension. Activation by experimental oral therapies.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Upregulation of lung soluble guanylate cyclase during chronic hypoxia is prevented by deletion of eNOS.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Soluble guanylate cyclase gene expression and localization in rat lung after exposure to hypoxia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Survival in patients with primary pulmonary hypertension. Results from a national prospective registry.

6 July 2018

1 reference

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Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Nitric oxide-independent stimulation of soluble guanylate cyclase reduces organ damage in experimental low-renin and high-renin models

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: a phase II study.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Simvastatin causes endothelial cell apoptosis and attenuates severe pulmonary hypertension.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Activation of soluble guanylate cyclase reverses experimental pulmonary hypertension and vascular remodeling

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Antiproliferative effects of phosphodiesterase type 5 inhibition in human pulmonary artery cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Efficacy and optimal dose of sildenafil in primary pulmonary hypertension

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Soluble guanylate cyclase activator reverses acute pulmonary hypertension and augments the pulmonary vasodilator response to inhaled nitric oxide in awake lambs

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Antiremodeling effects of iloprost and the dual-selective phosphodiesterase 3/4 inhibitor tolafentrine in chronic experimental pulmonary hypertension

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Immediate and Long-term Hemodynamic and Clinical Effects of Sildenafil in Patients With Pulmonary Arterial Hypertension Receiving Vasodilator Therapy

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

sGC and PDE5 are elevated in lambs with increased pulmonary blood flow and pulmonary hypertension

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Relative contributions of endothelial, inducible, and neuronal NOS to tone in the murine pulmonary circulation.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

New index of combined systolic and diastolic myocardial performance: a simple and reproducible measure of cardiac function--a study in normals and dilated cardiomyopathy

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Phosphodiesterase isoforms in the pulmonary arterial circulation of the rat: changes in pulmonary hypertension

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Rodent models of PAH: are we there yet?

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422306

Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22912874

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Formation of plexiform lesions in experimental severe pulmonary arterial hypertension

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22912874

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Noninvasive evaluation of pulmonary hypertension by a pulsed Doppler technique

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22912874

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0043433

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference