(Q34390078)

1 August 2017

title

Functional genomics in Drosophila models of human disease (English)

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1 August 2017

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2

Damian C Crowther

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1 August 2017

Ko-Fan Chen

1

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1 August 2017

publication date

22 August 2012

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Briefings in functional genomics

1 August 2017

published in

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1 August 2017

volume

11

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1 August 2017

issue

5

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1 August 2017

page(s)

405-415

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https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

1 August 2017

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Comparative genomics of the eukaryotes

21 January 2018

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https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Anomalous levels of Cl- transporters in the hippocampal subiculum from temporal lobe epilepsy patients make GABA excitatory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Mutations in the K+/Cl- cotransporter gene kazachoc (kcc) increase seizure susceptibility in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Drosophila models of neurodegenerative diseases

21 January 2018

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https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Alzheimer's disease: insights from Drosophila melanogaster models

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Functional genomic analysis of the Wnt-wingless signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

A buoyancy-based screen of Drosophila larvae for fat-storage mutants reveals a role for Sir2 in coupling fat storage to nutrient availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

FlyBase 101--the basics of navigating FlyBase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

OrthoDisease: a database of human disease orthologs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Automatic clustering of orthologs and in-paralogs from pairwise species comparisons

21 January 2018

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https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

The art and design of genetic screens: Drosophila melanogaster

21 January 2018

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https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Transposable elements as tools for genomics and genetics in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

A modular misexpression screen in Drosophila detecting tissue-specific phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Genetic suppression of polyglutamine toxicity in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

The Toll-->NFkappaB signaling pathway mediates the neuropathological effects of the human Alzheimer's Abeta42 polypeptide in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

GAL4 system in Drosophila: a fly geneticist's Swiss army knife

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Application of the gene search system to screen for longevity genes in Drosophila.

21 January 2018

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https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Fenton chemistry and oxidative stress mediate the toxicity of the beta-amyloid peptide in a Drosophila model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Identifying genes that interact with Drosophila presenilin and amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Biases in Drosophila melanogaster protein trap screens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

P[acman]: a BAC transgenic platform for targeted insertion of large DNA fragments in D. melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Drosophila genome-wide RNAi screens: are they delivering the promise?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

The art and design of genetic screens: RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Genome-wide RNAi analysis of growth and viability in Drosophila cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Genome-wide survey of protein kinases required for cell cycle progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

RNAi screening in Drosophila cells identifies new modifiers of mutant huntingtin aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

High-content chemical and RNAi screens for suppressors of neurotoxicity in a Huntington's disease model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Genome-wide RNAi screen for host factors required for intracellular bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Drosophila genome-wide RNAi screen identifies multiple regulators of HIF-dependent transcription in hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

A large-scale RNAi screen identifies Deaf1 as a regulator of innate immune responses in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Identification of genes required for neural-specific glycosylation using functional genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Prevalence of off-target effects in Drosophila RNA interference screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Using FlyAtlas to identify better Drosophila melanogaster models of human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Function-informed transcriptome analysis of Drosophila renal tubule

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Isolation of gene sets affected specifically by polyglutamine expression: implication of the TOR signaling pathway in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Perturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Next-generation DNA sequencing methods

21 January 2018

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https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Identification of novel non-coding RNAs using profiles of short sequence reads from next generation sequencing data

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

The developmental transcriptome of Drosophila melanogaster

21 January 2018

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https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Identification of functional elements and regulatory circuits by Drosophila modENCODE

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Deep mRNA sequencing for in vivo functional analysis of cardiac transcriptional regulators: application to Galphaq

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

A protein interaction map of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

In vivo analysis of proteomes and interactomes using Parallel Affinity Capture (iPAC) coupled to mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

A protein complex network of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

The BioGRID Interaction Database: 2011 update

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

DroID 2011: a comprehensive, integrated resource for protein, transcription factor, RNA and gene interactions for Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Huntingtin interacting proteins are genetic modifiers of neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Stability and dynamics of polycomb target sites in Drosophila development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Genome-wide polycomb target gene prediction in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

The tumour suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Epigenetic regulation of learning and memory by Drosophila EHMT/G9a

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

The ENCODE (ENCyclopedia Of DNA Elements) Project

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Unlocking the secrets of the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

DAnCER: disease-annotated chromatin epigenetics resource

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

Detection of early locomotor abnormalities in a Drosophila model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS038

21 January 2018

Identifiers

DOI

10.1093/BFGP/ELS038

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1 August 2017

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