(Q34391862)

1 August 2017

title

Pim-1 knockdown potentiates paclitaxel-induced apoptosis in human hormone-refractory prostate cancers through inhibition of NHEJ DNA repair (English)

1 reference

1 August 2017

1 reference

Jui-Ling Hsu

1

1 reference

1 August 2017

Pui-Kei Leong

2

1 reference

1 August 2017

Yunn-Fang Ho

3

1 reference

1 August 2017

Lih-Ching Hsu

4

1 reference

1 August 2017

Pin-Hsuan Lu

5

1 reference

1 August 2017

Ching-Shih Chen

6

1 reference

1 August 2017

Jih-Hwa Guh

7

1 reference

1 August 2017

language of work or name

English

0 references

publication date

17 January 2012

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1 August 2017

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1 August 2017

volume

319

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1 August 2017

issue

2

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1 August 2017

page(s)

214-222

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describes a project that uses

1 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4207118/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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DNA strand breaks and hypoxia response inhibition mediate the radiosensitisation effect of nitric oxide donors on prostate cancer under varying oxygen conditions.

6 July 2018

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Microtubule-Targeted Chemotherapeutic Agents Inhibit Signal Transducer and Activator of Transcription 3 (STAT3) Signaling

6 July 2018

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6 July 2018

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6 July 2018

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Prognostic impact of protein overexpression of the proto-oncogene PIM-1 in gastric cancer

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6 July 2018

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MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX.

6 July 2018

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Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes

6 July 2018

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PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells

6 July 2018

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Potential roles for the PIM1 kinase in human cancer - a molecular and therapeutic appraisal

6 July 2018

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Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels

6 July 2018

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The PIM1 kinase is a critical component of a survival pathway activated by docetaxel and promotes survival of docetaxel-treated prostate cancer cells.

6 July 2018

1 reference

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A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases

6 July 2018

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Changes in the level and distribution of Ku proteins during cellular senescence.

6 July 2018

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Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase

6 July 2018

1 reference

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Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL

6 July 2018

1 reference

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The 44 kDa Pim-1 kinase directly interacts with tyrosine kinase Etk/BMX and protects human prostate cancer cells from apoptosis induced by chemotherapeutic drugs

6 July 2018

1 reference

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Pim family kinases enhance tumor growth of prostate cancer cells

6 July 2018

1 reference

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The serine/threonine kinase Pim-1

6 July 2018

1 reference

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6 July 2018

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Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

6 July 2018

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Pim-1: a serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207118

Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207118

The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207118

Enforced expression of the Mr 33,000 Pim-1 kinase enhances factor-independent survival and inhibits apoptosis in murine myeloid cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207118

The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207118

Overexpression of PIM-1 is a potential biomarker in prostate carcinoma

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207118

Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207118

Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207118

Pim-1 expression in prostatic intraepithelial neoplasia and human prostate cancer

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207118

DNA damage induced by paclitaxel and DNA repair capability of peripheral blood lymphocytes as evaluated by the alkaline comet assay

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207118

ATM protein overexpression in prostate tumors: possible role in telomere maintenance.

27 October 2018

1 reference

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Expression of human pim family genes is selectively up-regulated by cytokines promoting T helper type 1, but not T helper type 2, cell differentiation

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22261337

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22261337

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CANLET.2012.01.004

1 reference

1 August 2017

1 reference

1 August 2017

1 reference