(Q34393182)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15705580%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase functions through a general acid-base catalyst pair mechanism (English)

1 reference

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8 January 2020

1

1 reference

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8 January 2020

6

Carol A Fierke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15705580%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

Heather A Gennadios

2

1 reference

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8 January 2020

Douglas A Whittington

3

1 reference

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8 January 2020

Kristin M Rusche

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15705580%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

David W Christianson

5

1 reference

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8 January 2020

language of work or name

English

0 references

publication date

10 February 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15705580%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

8 January 2020

published in

1 reference

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8 January 2020

volume

280

1 reference

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8 January 2020

page(s)

16969-16978

1 reference

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8 January 2020

issue

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15705580%20AND%20SRC:MED&resulttype=core&format=json

Lipopolysaccharide endotoxins

8 January 2020

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Antibacterial and anti-inflammatory agents that target endotoxin.

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Novel therapies for sepsis: antiendotoxin therapies

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UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase of Escherichia coli is a zinc metalloenzyme

21 January 2018

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Inhibition of the antibacterial target UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC): isoxazoline zinc amidase inhibitors bearing diverse metal binding groups

21 January 2018

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Antibacterial activities and characterization of novel inhibitors of LpxC.

21 January 2018

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Zinc hydrolases: the mechanisms of zinc-dependent deacetylases

21 January 2018

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Crystal structure of LpxC, a zinc-dependent deacetylase essential for endotoxin biosynthesis

21 January 2018

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Structure of the LpxC deacetylase with a bound substrate-analog inhibitor.

21 January 2018

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Site-directed mutagenesis of the bacterial metalloamidase UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC). Identification of the zinc binding site

21 January 2018

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Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

21 January 2018

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Kinetic analysis of the zinc-dependent deacetylase in the lipid A biosynthetic pathway

21 January 2018

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The envA permeability/cell division gene of Escherichia coli encodes the second enzyme of lipid A biosynthesis. UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase

21 January 2018

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EXAFS studies of the zinc sites of UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC).

21 January 2018

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Regulation of UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase in Escherichia coli. The second enzymatic step of lipid a biosynthesis.

21 January 2018

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AMoRe: an automated package for molecular replacement

21 January 2018

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Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

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The finer things in X-ray diffraction data collection

21 January 2018

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An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

21 January 2018

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Refined solution structure of the LpxC-TU-514 complex and pKa analysis of an active site histidine: insights into the mechanism and inhibitor design.

21 January 2018

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Leukotriene A4 hydrolase: abrogation of the peptidase activity by mutation of glutamic acid-296

21 January 2018

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Quantitative interpretations of double mutations of enzymes

21 January 2018

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Inverse thinking about double mutants of enzymes

21 January 2018

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Serine protease mechanism and specificity

21 January 2018

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

20 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1107/S0907444998003254

Identifiers

DOI

10.1074/JBC.M413560200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15705580%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference