(Q34398451)

1 August 2017

GSK2578215A; a potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor (English)

1 reference

1 August 2017

Jinwei Zhang

9

0 references

Dario Alessi

object named as

Dario R Alessi

10

0 references

Nathanael Gray

11

object named as

Nathanael S Gray

1 reference

1 August 2017

8

Xianming Deng

1 reference

1 August 2017

1

Alastair D Reith

1 reference

1 August 2017

7

Hwan Geun Choi

1 reference

1 August 2017

Paul Bamborough

2

1 reference

1 August 2017

Karamjit Jandu

3

1 reference

1 August 2017

Daniele Andreotti

4

1 reference

1 August 2017

Lucy Mensah

5

1 reference

1 August 2017

Pamela Dossang

6

1 reference

1 August 2017

language of work or name

English

0 references

publication date

7 July 2012

1 reference

Bioorganic & Medicinal Chemistry Letters

1 August 2017

1 reference

1 August 2017

22

1 reference

1 August 2017

17

1 reference

1 August 2017

5625-5629

1 reference

Characterization of TAE684 as a potent LRRK2 kinase inhibitor

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208292

Role of LRRK2 kinase dysfunction in Parkinson disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208292

On the road to leucine-rich repeat kinase 2 signalling: evidence from cellular and in vivo studies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208292

Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208292

Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser(910)/Ser(935), disruption of 14-3-3 binding and altered cytoplasmic localization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208292

LRRK2 and Parkinson disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208292

Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208292

Leucine-rich repeat kinase 2 mutations and Parkinson's disease: three questions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208292

Leucine-rich repeat kinase 2 (LRRK2): a key player in the pathogenesis of Parkinson's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208292

Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208292

The selectivity of protein kinase inhibitors: a further update

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208292

Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208292

A small molecule-kinase interaction map for clinical kinase inhibitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208292

Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson's disease-related toxicity in human neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208292

10.1016/J.BMCL.2012.06.104

27 October 2018

Identifiers

DOI

1 reference

1 August 2017

1 reference

1 August 2017

1 reference