(Q34399914)

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A new twist on an old idea part 2: cyclosporine preserves normal mitochondrial but not cardiomyocyte function in mini-swine with compensated heart failure

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21 March 2020

A new twist on an old idea part 2: cyclosporine preserves normal mitochondrial but not cardiomyocyte function in mini-swine with compensated heart failure (English)

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21 March 2020

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Manuel Gutiérrez-Aguilar

2

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21 March 2020

Timothy L. Domeier

9

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21 March 2020

author name string

Jessica A Hiemstra

1

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21 March 2020

Kurt D Marshall

3

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21 March 2020

Kyle S McCommis

4

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21 March 2020

Pamela J Zgoda

5

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21 March 2020

Noelany Cruz-Rivera

6

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21 March 2020

Nathan T Jenkins

7

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21 March 2020

Maike Krenz

8

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21 March 2020

Christopher P Baines

10

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21 March 2020

Craig A Emter

11

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21 March 2020

publication date

24 June 2014

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21 March 2020

Physiological Reports

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21 March 2020

2

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21 March 2020

6

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21 March 2020

describes a project that uses

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11 June 2022

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Genetic manipulation of the cardiac mitochondrial phosphate carrier does not affect permeability transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

A new twist on an old idea: a two-dimensional speckle tracking assessment of cyclosporine as a therapeutic alternative for heart failure with preserved ejection fraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

How to calculate sample size and why

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

The mitochondrial permeability transition pore: a mystery solved?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Effects of exercise on left ventricular systolic and diastolic properties in patients with heart failure and a preserved ejection fraction versus heart failure and a reduced ejection fraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Heart failure with preserved ejection fraction: chronic low-intensity interval exercise training preserves myocardial O2 balance and diastolic function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Altered sarcoplasmic reticulum calcium cycling--targets for heart failure therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

No rest for the weary: diastolic calcium homeostasis in the normal and failing myocardium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Length and PKA Dependence of Force Generation and Loaded Shortening in Porcine Cardiac Myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Pathogenesis of calcineurin inhibitor-induced hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Hypercholesterolemia increases mitochondrial oxidative stress and enhances the MPT response in the porcine myocardium: beneficial effects of chronic exercise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Low-intensity interval exercise training attenuates coronary vascular dysfunction and preserves Ca²⁺-sensitive K⁺ current in miniature swine with LV hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Diastolic and systolic heart failure are distinct phenotypes within the heart failure spectrum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Decreased cardiac functional reserve in heart failure with preserved systolic function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Heart failure with preserved ejection fraction: pathophysiology, diagnosis, and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Early development of intracellular calcium cycling defects in intact hearts of spontaneously hypertensive rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Low-intensity aerobic interval training attenuates pathological left ventricular remodeling and mitochondrial dysfunction in aortic-banded miniature swine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Elevated cytosolic Na+ increases mitochondrial formation of reactive oxygen species in failing cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Treatment of heart failure with normal ejection fraction: an inconvenient truth!

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Effect of cyclosporine on blood pressure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Mitochondrial permeability transition pore opening as a promising therapeutic target in cardiac diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Heart failure with normal left ventricular ejection fraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Apoptotic and non-apoptotic programmed cardiomyocyte death in ventricular remodelling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Role of persistence of antigen and indirect recognition in the maintenance of tolerance to renal allografts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the [...]

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Death begets failure in the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Energy metabolism in heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Cardiac hypertrophy: the good, the bad, and the ugly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Myocardial energetics in cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Low power, type II errors, and other statistical problems in recent cardiovascular research.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Depressed intracellular calcium transients and contraction in myocytes from hypertrophied and failing guinea pig hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

6 July 2018

Inhibition of complex I regulates the mitochondrial permeability transition through a phosphate-sensitive inhibitory site masked by cyclophilin D.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

27 October 2018

Mortality in heart failure with preserved ejection fraction: an unacceptably high rate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

27 October 2018

Doxorubicin-induced cardiac dysfunction is attenuated by ciclosporin treatment in mice through improvements in mitochondrial bioenergetics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

27 October 2018

The pathophysiology of heart failure with normal ejection fraction: exercise echocardiography reveals complex abnormalities of both systolic and diastolic ventricular function involving torsion, untwist, and longitudinal motion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

27 October 2018

Effect of cyclosporine on reperfusion injury in acute myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

27 October 2018

Effects of cyclosporine, tacrolimus and sirolimus on vascular changes related to immune response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

27 October 2018

Low-intensity exercise training delays onset of decompensated heart failure in spontaneously hypertensive heart failure rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

27 October 2018

Enhanced sarcolemmal Ca2+ efflux reduces sarcoplasmic reticulum Ca2+ content and systolic Ca2+ in cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

27 October 2018

Increased regulatory activity of the calcineurin/NFAT pathway in human heart failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

27 October 2018

Time-dependent systolic and diastolic function in mice overexpressing calcineurin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

27 October 2018

Calcineurin and human heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208639

9 December 2018

Activation of the calcineurin/NFAT signalling cascade starts early in human hypertrophic myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/24963034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/24963034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

M cells and transmural heterogeneity of action potential configuration in myocytes from the left ventricular wall of the pig heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/24963034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium transients in feline left ventricular myocytes with hypertrophy induced by slow progressive pressure overload

1 reference

https://pubmed.ncbi.nlm.nih.gov/24963034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular mechanisms of altered contractility in the hypertrophied heart: big hearts, big sparks

1 reference

https://pubmed.ncbi.nlm.nih.gov/24963034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential Activation of Signal Transduction Pathways in Human Hearts With Hypertrophy Versus Advanced Heart Failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/24963034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guidelines for reporting statistics in journals published by the American Physiological Society

1 reference

https://pubmed.ncbi.nlm.nih.gov/24963034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigation of the mechanisms underlying the increased contraction of hypertrophied ventricular myocytes isolated from the spontaneously hypertensive rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/24963034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.14814/PHY2.12050

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24963034%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24963034%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24963034%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

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