(Q33723923)

28 July 2017

title

Pathogenesis of calcineurin inhibitor-induced hypertension (English)

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28 July 2017

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Ewout J Hoorn

1

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28 July 2017

Stephen B Walsh

2

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28 July 2017

James A McCormick

3

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28 July 2017

Robert Zietse

4

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28 July 2017

Robert J Unwin

5

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28 July 2017

David H Ellison

6

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28 July 2017

publication date

1 May 2012

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28 July 2017

published in

Journal of Nephrology

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28 July 2017

volume

25

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28 July 2017

issue

3

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28 July 2017

page(s)

269-275

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Pathogenesis and management of hypertension after kidney transplantation

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension

14 July 2018

1 reference

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A SPAK isoform switch modulates renal salt transport and blood pressure

14 July 2018

1 reference

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Renal nerves, WNK4, glucocorticoids, and salt transport

14 July 2018

1 reference

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Epigenetic modulation of the renal β-adrenergic-WNK4 pathway in salt-sensitive hypertension

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

HNF4alpha dysfunction as a molecular rational for cyclosporine induced hypertension

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Regulation of sodium transporters in the kidney during cyclosporine treatment.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction

14 July 2018

1 reference

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Effect of cyclosporine on blood pressure

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Chronic calcineurin inhibitor nephrotoxicity: reflections on an evolving paradigm

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Cyclosporine stimulates the renal epithelial sodium channel by elevating cholesterol

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Conditional fast expression and function of multimeric TRPV5 channels using Shield-1.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Vascular tone control in humans: insights from studies in Bartter's/Gitelman's syndromes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Familial hyperkalemic hypertension

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Molecular targets for existing and novel immunosuppressive drugs

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Role of angiotensin II and reactive oxygen species in cyclosporine A-dependent hypertension

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Interaction of cyclosporine A and the renin-angiotensin system; new perspectives

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Human hypertension caused by mutations in WNK kinases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Cyclosporine A-induced hypertension involves synapsin in renal sensory nerve endings

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Endothelial dysfunction in renal transplant recipients maintained on cyclosporine

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Cyclosporine A up-regulates angiotensin II receptors and calcium responses in human vascular smooth muscle cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Mechanisms of FK 506-induced hypertension in the rat.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Cellular functions of immunophilins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Effects of endothelin receptor antagonist on cyclosporine-induced vasoconstriction in isolated rat renal arterioles

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Vascular mechanisms of cyclosporin-induced hypertension in the rat

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Urinary endothelin and renal vasoconstriction with cyclosporine or FK506 after liver transplantation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Effect of cyclosporine administration on renal hemodynamics in conscious rats.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Intravenous cyclosporine activates afferent and efferent renal nerves and causes sodium retention in innervated kidneys in rats

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Hypertension in cyclosporine-treated renal transplant recipients is sodium dependent

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Sympathoexcitation in calcineurin inhibitor-induced hypertension: villain or innocent bystander?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Differential effects of acute and sustained cyclosporine and tacrolimus on sympathetic nerve activity

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

The calcineurin inhibitor FK506 (tacrolimus) is associated with transient metabolic acidosis and altered expression of renal acid-base transport proteins.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Inhibition of mineralocorticoid receptors with eplerenone alleviates short-term cyclosporin A nephrotoxicity in conscious rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Transient activation of calcineurin is essential to initiate embryonic development in Xenopus laevis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Salt sensitivity of blood pressure in patients with psoriasis on ciclosporin therapy.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Hypertension after kidney transplantation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Oral cyclosporine but not tacrolimus reduces renal transplant blood flow

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Conversion from cyclosporine to tacrolimus improves quality-of-life indices, renal graft function and cardiovascular risk profile

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Aldosterone resistance in kidney transplantation is in part induced by a down-regulation of mineralocorticoid receptor expression

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Improved cardiovascular risk profile and renal function in renal transplant patients after randomized conversion from cyclosporine to tacrolimus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Cyclosporine a and FK506 inhibit transcriptional activity of the human mineralocorticoid receptor: a cell-based model to investigate partial aldosterone resistance in kidney transplantation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

What have we learned about primary liver transplantation under tacrolimus immunosuppression? Long-term follow-up of the first 1000 patients.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Hypertension in cyclosporin A-treated patients is independent of circulating endothelin levels.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Renal sodium handling with cyclosporin A and FK506 after orthotopic liver transplantation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Cyclosporine A enhances renin secretion and production in isolated juxtaglomerular cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Endothelin mediates the renal vasoconstriction induced by cyclosporine in the rat

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Hypertension after kidney transplantation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Cyclosporin-induced hypertension precedes renal dysfunction and sodium retention in man

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4048819

Cyclosporin A inhibits nitric oxide synthase induction in vascular smooth muscle cells

30 October 2018

1 reference

12 December 2020

Cyclosporine-induced hypertension after transplantation

1 reference

12 December 2020

The acute effects of FK-506 on renal haemodynamics, water and sodium excretion and plasma levels of angiotensin II, aldosterone, atrial natriuretic peptide and vasopressin in pigs

1 reference

12 December 2020

Effects of an endothelin receptor antagonist in rats with cyclosporine-induced hypertension

1 reference

12 December 2020

The sodium retaining effects of cyclosporine

1 reference

12 December 2020

HYPERTENSION AND HYPERPOTASSAEMIA WITHOUT RENAL DISEASE IN A YOUNG MALE

1 reference

12 December 2020

Different effects of cyclosporine a and FK506 on potassium transport systems in MDCK cells

1 reference

12 December 2020

Contribution of endothelin receptors in renal microvessels in acute cyclosporine-mediated vasoconstriction in rats

1 reference

12 December 2020

Ciclosporin-induced hypertension is associated with increased sodium transporter of the loop of Henle (NKCC2)

1 reference

12 December 2020

Modulation of abnormalities in renal haemodynamics and vasoactive mediators by nifedipine in patients with psoriasis on low-dose cyclosporin

1 reference

12 December 2020

Cyclosporine metabolic side effects: association with the WNK4 system

1 reference

12 December 2020

A thiazide test for the diagnosis of renal tubular hypokalemic disorders

1 reference

12 December 2020

Systemic and renal hemodynamic differences between FK506 and cyclosporine in liver transplant recipients

1 reference

12 December 2020

Cyclosporine therapy after cardiac transplantation causes hypertension and renal vasoconstriction without sympathetic activation

1 reference

12 December 2020

Hypertension after kidney transplantation: calcineurin inhibitors increase salt-sensitivity

1 reference

12 December 2020

Cyclosporine A inhibits relaxation but does not induce vasoconstriction in human subcutaneous resistance vessels

1 reference

12 December 2020

Hypertension after renal transplantation and polymorphism of genes involved in essential hypertension: ACE, AGT, AT1 R and ecNOS

1 reference

12 December 2020

Identifiers

DOI

10.5301/JN.5000174

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28 July 2017

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28 July 2017

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