(Q34401495)

1 August 2017

title

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice (English)

1 reference

1 August 2017

0 references

Xia Xu

3

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Emil Ylikallio

object named as

Emil Ylikallio

1

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Henna Tyynismaa

object named as

Henna Tyynismaa

7

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author name string

Jennifer L Page

2

1 reference

1 August 2017

Milla Lampinen

4

1 reference

1 August 2017

Gerold Bepler

5

1 reference

1 August 2017

Tomomi Ide

6

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1 August 2017

Robert S Weiss

8

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1 August 2017

Anu Suomalainen

9

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1 August 2017

language of work or name

English

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publication date

19 August 2010

1 reference

1 August 2017

published in

Nucleic Acids Research

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1 August 2017

volume

38

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1 August 2017

issue

22

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1 August 2017

page(s)

8208-8218

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Creative Commons Attribution-NonCommercial 2.5 Generic

1 August 2017

copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3001089/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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6 July 2018

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6 July 2018

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A heterozygous truncating mutation in RRM2B causes autosomal-dominant progressive external ophthalmoplegia with multiple mtDNA deletions

6 July 2018

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Unbalanced deoxynucleotide pools cause mitochondrial DNA instability in thymidine phosphorylase-deficient mice

6 July 2018

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Thymidine kinase 2 (H126N) knockin mice show the essential role of balanced deoxynucleotide pools for mitochondrial DNA maintenance.

6 July 2018

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6 July 2018

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Broad overexpression of ribonucleotide reductase genes in mice specifically induces lung neoplasms

6 July 2018

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6 July 2018

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The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures

6 July 2018

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Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion

6 July 2018

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p53R2-dependent ribonucleotide reduction provides deoxyribonucleotides in quiescent human fibroblasts in the absence of induced DNA damage.

6 July 2018

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Targeted transgenic overexpression of mitochondrial thymidine kinase (TK2) alters mitochondrial DNA (mtDNA) and mitochondrial polypeptide abundance: transgenic TK2, mtDNA, and antiretrovirals

6 July 2018

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Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae.

6 July 2018

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6 July 2018

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6 July 2018

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Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice

6 July 2018

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The conserved Mec1/Rad53 nuclear checkpoint pathway regulates mitochondrial DNA copy number in Saccharomyces cerevisiae

6 July 2018

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Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number

6 July 2018

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6 July 2018

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Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools

6 July 2018

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6 July 2018

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6 July 2018

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Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy

6 July 2018

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The deoxyguanosine kinase gene is mutated in individuals with depleted hepatocerebral mitochondrial DNA

6 July 2018

1 reference

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Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells

6 July 2018

1 reference

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A ribonucleotide reductase gene is a transcriptional target of p53 and p73

6 July 2018

1 reference

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A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001089

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6 July 2018

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Ribonucleotide reductase R2 component is a novel malignancy determinant that cooperates with activated oncogenes to determine transformation and malignant potential

6 July 2018

1 reference

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The problem of tissue sampling from experimental animals with respect to freezing technique, anoxia, stress and narcosis. A new method for sampling rat liver tissue and the physiological values of glycolytic intermediates and related compounds.

6 July 2018

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Interactions between deoxyribonucleotide and DNA synthesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001089

6 July 2018

1 reference

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Distribution and threshold expression of the tRNA(Lys) mutation in skeletal muscle of patients with myoclonic epilepsy and ragged-red fibers (MERRF)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001089

In vitro supplementation with dAMP/dGMP leads to partial restoration of mtDNA levels in mitochondrial depletion syndromes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001089

Genetic and chemical rescue of the Saccharomyces cerevisiae phenotype induced by mitochondrial DNA polymerase mutations associated with progressive external ophthalmoplegia in humans.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001089

Intracellular nucleotide and nucleotide sugar contents of cultured CHO cells determined by a fast, sensitive, and high-resolution ion-pair RP-HPLC.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001089

Mitochondrial transcription factor A regulates mtDNA copy number in mammals

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001089

Dynamics of DNA replication in mammalian somatic cells: nucleotide pool modulates origin choice and interorigin spacing.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001089

Mitochondrial and cytosolic ATP/ADP ratios in rat liver in vivo

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001089

Defects in maintenance of mitochondrial DNA are associated with intramitochondrial nucleotide imbalances

27 October 2018

1 reference

12 December 2020

High mitochondrial DNA copy number has detrimental effects in mice

1 reference

12 December 2020

Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers

1 reference

12 December 2020

Overexpression of mitochondrial transcription factor a ameliorates mitochondrial deficiencies and cardiac failure after myocardial infarction

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKQ735

1 reference

1 August 2017

1 reference

1 August 2017

1 reference