(Q34403471)

1 August 2017

title

Inhibition of human cytochrome P450 2D6 (CYP2D6) by methadone (English)

1 reference

1 August 2017

Wu D

1

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1 August 2017

Otton SV

2

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1 August 2017

Sproule BA

3

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1 August 2017

Busto U

4

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1 August 2017

Inaba T

5

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1 August 2017

Kalow W

6

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1 August 2017

Sellers EM

7

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1 August 2017

language of work or name

English

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publication date

1 January 1993

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British Journal of Clinical Pharmacology

1 August 2017

published in

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1 August 2017

volume

35

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1 August 2017

issue

1

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1 August 2017

page(s)

30-34

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Substrate specificity of the form of cytochrome P-450 catalyzing the 4-hydroxylation of debrisoquine in man

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

The biotransformation of methadone in man: synthesis and identification of a major metabolite.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

Pharmacokinetics and pharmacodynamics of methadone in patients with chronic pain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

Quinidine: potent inhibition of sparteine and debrisoquine oxidation in vivo.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

MPTP, the neurotoxin inducing Parkinson's disease, is a potent competitive inhibitor of human and rat cytochrome P450 isozymes (P450bufI, P450db1) catalyzing debrisoquine 4-hydroxylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

Polymorphism of dextromethorphan oxidation in a French population

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

In vitro inhibition of a polymorphic human liver P-450 isozyme by narcotic analgesics.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

Increase in desipramine serum levels associated with methadone treatment.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

A dose-effect study of the in vivo inhibitory effect of quinidine on sparteine oxidation in man.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

Simultaneous determination of dextromethorphan and three metabolites in plasma and urine using high-performance liquid chromatography with application to their disposition in man.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

Polymorphic formation of morphine from codeine in poor and extensive metabolizers of dextromethorphan: relationship to the presence of immunoidentified cytochrome P-450IID1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

Evidence for altered desipramine disposition in methadone-maintained patients treated for cocaine abuse

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

The genetic polymorphism of debrisoquine/sparteine metabolism--clinical aspects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

Genetic polymorphism of sparteine/debrisoquine oxidation: a reappraisal

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

Impact of environmental and genetic factors on codeine analgesia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

Molecular genetics of the debrisoquin-sparteine polymorphism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

Interindividual and interspecies variation in the metabolism of the hallucinogen 4-methoxyamphetamine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381486

A treatment crisis: cocaine use by clients in methadone maintenance programs

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1993.TB05666.X

Codeine o-demethylation: Rat strain differences and the effects of inhibitors

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1993.TB05666.X

Competitive inhibition of sparteine oxidation in human liver by β-adrenoceptor antagonists and other cardiovascular drugs

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1993.TB05666.X

The levels of methadone in the plasma in methadone maintenance

21 January 2018

1 reference

12 December 2020

Inhibition of sparteine oxidation in human liver by tricyclic antidepressants and other drugs

1 reference

12 December 2020

In vitro inhibition studies of two isozymes of human liver cytochrome P-450. Mephenytoin p-hydroxylase and sparteine monooxygenase

1 reference

12 December 2020

Polymorphic dextromethorphan metabolism: co-segregation of oxidative O-demethylation with debrisoquin hydroxylation

1 reference

12 December 2020

Single-dose quinidine treatment inhibits metoprolol oxidation in extensive metabolizers

1 reference

12 December 2020

Differential effects of cimetidine and ranitidine on imipramine demethylation and desmethylimipramine hydroxylation by human liver microsomes

1 reference

12 December 2020

Biotransformation of caffeine, paraxanthine, theophylline, and theobromine by polycyclic aromatic hydrocarbon-inducible cytochrome(s) P-450 in human liver microsomes

1 reference

12 December 2020

Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufI)

1 reference

12 December 2020

Xenobiotic and endobiotic inhibitors of cytochrome P-450dbl function, the target of the debrisoquine/sparteine type polymorphism

1 reference

12 December 2020

Dextromethorphan O-demethylation in liver microsomes as a prototype reaction to monitor cytochrome P-450 db1 activity

1 reference

12 December 2020

Evidence in humans for variant allozymes of the nondeficient sparteine/debrisoquine monooxygenase (P45OIID 1) in vitro

1 reference

12 December 2020

Clinical significance of the sparteine/debrisoquine oxidation polymorphism

1 reference

12 December 2020

Dextromethorphan oxidation phenotypes as markers for susceptibility to lung cancer

1 reference

12 December 2020

Serum levels of methadone in maintenance clients who persist in illicit drug use

1 reference

12 December 2020

Synthesis and identification of metabolites resulting from the biotransformation of DL-methadone in man and in the rat

1 reference

12 December 2020

10.1111/J.1365-2125.1993.TB05666.X

Identifiers

DOI

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1 August 2017

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1 August 2017

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