(Q34405484)

2 August 2017

1 reference

title

In vivo analysis of the molecular genetics of acute promyelocytic leukemia (English)

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2 August 2017

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P P Pandolfi

1

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PubMed ID

11607822

2 August 2017

language of work or name

English

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publication date

1 September 2001

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2 August 2017

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2 August 2017

20

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2 August 2017

40

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2 August 2017

5726-5735

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204600

2 August 2017

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cites work

Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Plzf regulates limb and axial skeletal patterning

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

The POZ domain: a conserved protein-protein interaction motif

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

A PMLRARalpha transgene initiates murine acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Characterization of a Fusion cDNA (RARA/myl) Transcribed from the t(15;17) Translocation Breakpoint in Acute Promyelocytic Leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Transgenic expression of PML/RARalpha impairs myelopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Characterization of a Zinc Finger Gene Disrupted by the t(15;17) in Acute Promyelocytic Leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Early myeloid cell-specific expression of the human cathepsin G gene in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Histone acetylation in chromatin structure and transcription

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

In vivo analysis of the molecular pathogenesis of acute promyelocytic leukemia in the mouse and its therapeutic implications

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Two critical hits for promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

BCL-2 cooperates with promyelocytic leukemia retinoic acid receptor alpha chimeric protein (PMLRARalpha) to block neutrophil differentiation and initiate acute leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Retinoic acid, but not arsenic trioxide, degrades the PLZF/RARalpha fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17)(q23;q21) APL patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

bcl-2 inhibits apoptosis of neutrophils but not their engulfment by macrophages

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Sequence-specific DNA binding and transcriptional regulation by the promyelocytic leukemia zinc finger protein.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Role of the histone deacetylase complex in acute promyelocytic leukaemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Formation of nucleophosmin/B23 oligomers requires both the amino- and the carboxyl-terminal domains of the protein.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

21 January 2018

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Transcription therapy for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

A bcr-3 isoform of RARalpha-PML potentiates the development of PML-RARalpha-driven acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Role of promyelocytic leukemia (PML) protein in tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

The RAR alpha-PLZF chimera associated with Acute Promyelocytic Leukemia has retained a sequence-specific DNA-binding domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Retinoids in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Fusion of retinoic acid receptor alpha to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

The growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

A role for PML and the nuclear body in genomic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

Acquired, nonrandom chromosomal abnormalities associated with the development of acute promyelocytic leukemia in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

The signal transducer and activator of transcription STAT5b gene is a new partner of retinoic acid receptor alpha in acute promyelocytic-like leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

7 January 2021

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

7 January 2021

The function of PML in p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

7 January 2021

PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

7 January 2021

Transcriptional regulation of cellular transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204600

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204600

1 reference

PubMed ID

11607822

Dimensions Publication ID

2 August 2017

0 references

1 reference

PubMed ID

11607822