(Q34405508)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11607829%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

review article

1 reference

title

The transmembrane adapter LAT plays a central role in immune receptor signalling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11607829%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

main subject

transmembrane protein

0 references

author

Steve P. Watson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11607829%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

author name string

Wonerow P

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11607829%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

language of work or name

English

0 references

publication date

1 October 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11607829%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11607829%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11607829%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

issue

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11607829%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

page(s)

6273-6283

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11607829%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204770

12 November 2019

exact match

0 references

cites work

Grf40, A novel Grb2 family member, is involved in T cell signaling through interaction with SLP-76 and LAT

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Interaction of linker for activation of T cells with multiple adapter proteins in platelets activated by the glycoprotein VI-selective ligand, convulxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Stimulation of Fc gamma RIIIA results in phospholipase C-gamma 1 tyrosine phosphorylation and p56lck activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Tyrosine phosphorylation coupled to IgE receptor-mediated signal transduction and histamine release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Adapter proteins SLP-76 and BLNK both are expressed by murine macrophages and are linked to signaling via Fcgamma receptors I and II/III

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Association of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

T cell receptor signalling results in rapid tyrosine phosphorylation of the linker protein LAT present in detergent-resistant membrane microdomains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Biochemical isolation of a membrane microdomain from resting platelets highly enriched in the plasma membrane glycoprotein CD36

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Signaling takes shape in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

BLNK: a central linker protein in B cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

T cell activation-dependent association between the p85 subunit of the phosphatidylinositol 3-kinase and Grb2/phospholipase C-gamma 1-binding phosphotyrosyl protein pp36/38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

CD16-mediated p21ras activation is associated with Shc and p36 tyrosine phosphorylation and their binding with Grb2 in human natural killer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor gamma-chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Sequential requirements of the N-terminal palmitoylation site and SH2 domain of Src family kinases in the initiation and progression of FcepsilonRI signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Involvement of LAT, Gads, and Grb2 in compartmentation of SLP-76 to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

The role of lipid rafts in T cell antigen receptor (TCR) signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Signal transduction by the TCR for antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Regulation of B cell function by linker proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Tyrosine phosphorylation of the linker for activator of T cells in mast cells by stimulation with the high affinity IgE receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Membrane rafts and signaling by the multichain immune recognition receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Localization of LAT in glycolipid-enriched microdomains is required for T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Insolubility of lipids in triton X-100: physical origin and relationship to sphingolipid/cholesterol membrane domains (rafts).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Molecules in focus: The c-Cbl oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Tyrosine phosphorylation of Grb2-associated proteins correlates with phospholipase C gamma 1 activation in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Constitutive activation of Src family kinases in mouse embryos that lack Csk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

The role of SLP-76 and LAT in lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Antigen receptor tail clue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Signals determining protein tyrosine kinase and glycosyl-phosphatidylinositol-anchored protein targeting to a glycolipid-enriched membrane fraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Tyrosine phosphorylation and translocation of LAT in platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Cell signaling by receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Integration of receptor-mediated signals in T cells by transmembrane adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Lipid rafts and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

From Src Homology domains to other signaling modules: proposal of the 'protein recognition code'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Fc gamma receptor activation induces the tyrosine phosphorylation of both phospholipase C (PLC)-gamma 1 and PLC-gamma 2 in natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Lymphocytes with a complex: adapter proteins in antigen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

A soluble LAT deletion mutant inhibits T-cell activation: reduced recruitment of signalling molecules to glycolipid-enriched microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

The role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

A novel association of Fc receptor gamma-chain with glycoprotein VI and their co-expression as a collagen receptor in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Killer cell inhibitory receptor recognition of human leukocyte antigen (HLA) class I blocks formation of a pp36/PLC-gamma signaling complex in human natural killer (NK) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Dual fatty acylation of p59(Fyn) is required for association with the T cell receptor zeta chain through phosphotyrosine-Src homology domain-2 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Stimulation through the T cell receptor leads to interactions between SHB and several signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Regulation of phospholipase C gamma isoforms in haematopoietic cells: why one, not the other?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Functional complementation of BLNK by SLP-76 and LAT linker proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

The kinase, SH3, and SH2 domains of Lck play critical roles in T-cell activation after ZAP-70 membrane localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Essential role of LAT in T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

7 January 2021

The p85 Subunit of Phosphatidylinositol 3-Kinase Associates with the Fc Receptor γ-Chain and Linker for Activitor of T Cells (LAT) in Platelets Stimulated by Collagen and Convulxin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

7 January 2021

Compartmentalization of phosphatidylinositol 4,5-bisphosphate in low-density membrane domains in the absence of caveolin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

7 January 2021

LAT is essential for Fc(epsilon)RI-mediated mast cell activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

7 January 2021

Yet another function for kinesin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

7 January 2021

Requirement for the SLP-76 adaptor GADS in T cell development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204770

7 January 2021