(Q34410588)

2 August 2017

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title

Gene therapy in epilepsy-is it time for clinical trials? (English)

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2 August 2017

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Robert C Wykes

4

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Stephanie Schorge

object named as

Stephanie Schorge

series ordinal

2

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Matthew C. Walker

object named as

Matthew C Walker

series ordinal

3

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Dimitri Kullmann

object named as

Dimitri M Kullmann

series ordinal

1

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language of work or name

English

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publication date

18 March 2014

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2 August 2017

Nature Reviews Neurology

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2 August 2017

10

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2 August 2017

5

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2 August 2017

300-304

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https://scigraph.springernature.com/pub.10.1038/nrneurol.2014.43

2 August 2017

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cites work

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Neuropeptide Y gene therapy decreases chronic spontaneous seizures in a rat model of temporal lobe epilepsy

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Localized delivery of fibroblast growth factor-2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model

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Adeno-associated virus-mediated expression and constitutive secretion of galanin suppresses limbic seizure activity in vivo

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Optogenetic and potassium channel gene therapy in a rodent model of focal neocortical epilepsy

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Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects

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Differential effects of left and right anterior temporal lobectomy on verbal learning and memory performance

21 January 2018

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Photothrombotic brain infarction results in seizure activity in aging Fischer 344 and Sprague Dawley rats.

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Electrobehavioral characteristics of epileptic rats following photothrombotic brain infarction.

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Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury

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Chronic focal epilepsy induced by microinjection of tetanus toxin into the cat motor cortex

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Therapeutic liabilities of in vivo viral vector tropism: adeno-associated virus vectors, NMDAR1 antisense, and focal seizure sensitivity

21 January 2018

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21 January 2018

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Oncolytic viruses as therapeutic cancer vaccines

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Seizure suppression by GDNF gene therapy in animal models of epilepsy

31 March 2020

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Neurological Channelopathies

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.43

Gene therapies need new development models

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.43

Injection parameters and virus dependent choice of promoters to improve neuron targeting in the nonhuman primate brain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.43

Development of gene therapy for neurological disorders

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24638133

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Gene therapies need new development models

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24638133

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRNEUROL.2014.43

1 reference

PubMed ID

24638133

Dimensions Publication ID

2 August 2017

0 references

1 reference

PubMed ID

24638133