(Q34411511)

2 August 2017

Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential. (English)

1 reference

2 August 2017

Satoshi Okada

6

0 references

author name string

Yoshinori Ohno

1

1 reference

2 August 2017

Shin'ichiro Yasunaga

2

1 reference

2 August 2017

Motoaki Ohtsubo

3

1 reference

2 August 2017

Sayaka Mori

4

1 reference

2 August 2017

Miyuki Tsumura

5

1 reference

2 August 2017

Tomohiko Ohta

7

1 reference

2 August 2017

Kiyoshi Ohtani

8

1 reference

2 August 2017

Masao Kobayashi

9

1 reference

2 August 2017

Yoshihiro Takihara

10

1 reference

2 August 2017

language of work or name

English

0 references

publication date

22 November 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

1 reference

2 August 2017

107

1 reference

2 August 2017

50

1 reference

2 August 2017

21529-21534

1 reference

Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity.

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

HOXB4's road map to stem cell expansion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

Cul4A is required for hematopoietic stem-cell engraftment and self-renewal

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

Geminin regulates neuronal differentiation by antagonizing Brg1 activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

Role of histone H2A ubiquitination in Polycomb silencing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

Molecular interactions involved in HOXB4-induced activation of HSC self-renewal

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

Replication licensing--defining the proliferative state?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

Cell type-specific E2F activation and cell cycle progression induced by the oncogene product Tax of human T-cell leukemia virus type I.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

Geminin, an inhibitor of DNA replication, is degraded during mitosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

Homeobox genes and axial patterning

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003101

HOXB4-induced expansion of adult hematopoietic stem cells ex vivo.

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1011054107

HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1011054107

In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1011054107

Roles for c-Myc in self-renewal of hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1011054107

E4F1: a novel candidate factor for mediating BMI1 function in primitive hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1011054107

Regulation of Geminin and Cdt1 expression by E2F transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1011054107

Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21098278

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1011054107

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference