(Q34413909)

2 August 2017

Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition. (English)

1 reference

2 August 2017

0 references

1 reference

5

Donald C Lo

1 reference

2 August 2017

Anan Yu

1

1 reference

2 August 2017

Yoko Shibata

2

1 reference

2 August 2017

Bijal Shah

3

1 reference

2 August 2017

Barbara Calamini

4

1 reference

2 August 2017

Richard I Morimoto

6

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 April 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

1 reference

2 August 2017

111

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2 August 2017

E1481-90

1 reference

2 August 2017

15

1 reference

describes a project that uses

2 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3992642/fullTextXML

inferred from PubMed Central ID database lookup

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6 July 2018

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Molecular mechanism and physiological functions of clathrin-mediated endocytosis

6 July 2018

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6 July 2018

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Identification of anti-inflammatory targets for Huntington's disease using a brain slice-based screening assay

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6 July 2018

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Composite primary neuronal high-content screening assay for Huntington's disease incorporating non-cell-autonomous interactions

6 July 2018

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Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging

6 July 2018

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Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis

6 July 2018

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6 July 2018

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The cell biology of synaptic plasticity: AMPA receptor trafficking

6 July 2018

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Multiple roles of auxilin and hsc70 in clathrin-mediated endocytosis

6 July 2018

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Molecular determinants for the interaction between AMPA receptors and the clathrin adaptor complex AP-2.

6 July 2018

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Progressive disruption of cellular protein folding in models of polyglutamine diseases.

6 July 2018

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Structural properties and neuronal toxicity of amyotrophic lateral sclerosis-associated Cu/Zn superoxide dismutase 1 aggregates.

6 July 2018

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Depletion of GAK/auxilin 2 inhibits receptor-mediated endocytosis and recruitment of both clathrin and clathrin adaptors

6 July 2018

1 reference

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Adaptors for clathrin coats: structure and function.

6 July 2018

1 reference

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Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD

6 July 2018

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Aggregation of expanded polyglutamine domain in yeast leads to defects in endocytosis

6 July 2018

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ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization

6 July 2018

1 reference

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Clathrin-mediated endocytosis in AP-2-depleted cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70

6 July 2018

1 reference

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Unfolding the role of protein misfolding in neurodegenerative diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity

6 July 2018

1 reference

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Disassembly of transcriptional regulatory complexes by molecular chaperones

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Role of AMPA receptor endocytosis in synaptic plasticity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Dominant-interfering Hsc70 mutants disrupt multiple stages of the clathrin-coated vesicle cycle in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Identification of the universal cofactor (auxilin 2) in clathrin coat dissociation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Role of Cyclin G-associated Kinase in Uncoating Clathrin-coated Vesicles from Non-neuronal Cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Adaptors for clathrin-mediated traffic

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Role of auxilin in uncoating clathrin-coated vesicles.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

The structure of an antigenic determinant in a protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Dissociation of clathrin coats coupled to the hydrolysis of ATP: role of an uncoating ATPase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

An enzyme that removes clathrin coats: purification of an uncoating ATPase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

100-kD coated vesicle proteins: molecular heterogeneity and intracellular distribution studied with monoclonal antibodies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Auxilin, a newly identified clathrin-associated protein in coated vesicles from bovine brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Folding and trimerization of clathrin subunits at the triskelion hub.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992642

Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1321811111

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1321811111

Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1321811111

Drosophila Hsc70-4 is critical for neurotransmitter exocytosis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1321811111

Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1321811111

Clathrin adaptor AP2 and NSF interact with overlapping sites of GluR2 and play distinct roles in AMPA receptor trafficking and hippocampal LTD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1321811111

Dendritic spine loss and neurodegeneration is rescued by Rab11 in models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1321811111

Signaling on the endocytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1321811111

Experimental demonstration of a universally valid error–disturbance uncertainty relation in spin measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1321811111

Polyglutamine protein aggregates are dynamic

21 January 2018

1 reference

12 December 2020

Small subclass of rat olfactory neurons with specific bulbar projections is reactive with monoclonal antibodies to the HSP70 heat shock protein

1 reference

12 December 2020

Interaction of auxilin with the molecular chaperone, Hsc70

1 reference

12 December 2020

Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1321811111

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference