(Q34414166)

2 August 2017

The p16(INK4A) tumor suppressor regulates cellular oxidative stress (English)

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2 August 2017

N C Jenkins

1

1 reference

2 August 2017

T Liu

2

1 reference

2 August 2017

P Cassidy

3

1 reference

2 August 2017

S A Leachman

4

1 reference

2 August 2017

K M Boucher

5

1 reference

2 August 2017

A G Goodson

6

1 reference

2 August 2017

G Samadashwily

7

1 reference

2 August 2017

D Grossman

8

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2 August 2017

language of work or name

English

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publication date

13 September 2010

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2 August 2017

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2 August 2017

30

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2 August 2017

3

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2 August 2017

265-274

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https://scigraph.springernature.com/pub.10.1038/onc.2010.419

2 August 2017

0 references

cites work

Melanocytes are deficient in repair of oxidative DNA damage and UV-induced photoproducts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Mitochondrial reactive oxygen species originating from Romo1 exert an important role in normal cell cycle progression by regulating p27(Kip1) expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Inhibition and genetic deficiency of p38 MAPK up-regulates heme oxygenase-1 gene expression via Nrf2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Oncogenic Braf induces melanocyte senescence and melanoma in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Oncogene-induced senescence does not require the p16(INK4a) or p14ARF melanoma tumor suppressors.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

p16INK4a-induced senescence is disabled by melanoma-associated mutations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Lentiviral transduction of mammary stem cells for analysis of gene function during development and cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Malignant blue nevus with lymph node metastases.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Survivin repression by p53, Rb and E2F2 in normal human melanocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

N-acetylcysteine protects melanocytes against oxidative stress/damage and delays onset of ultraviolet-induced melanoma in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Oncogene-induced cell senescence--halting on the road to cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Cellular senescence in naevi and immortalisation in melanoma: a role for p16?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

UV causation of melanoma in Xiphophorus is dominated by melanin photosensitized oxidant production

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Distinct sets of genetic alterations in melanoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

The tumor suppressor p16(INK4a) prevents cell transformation through inhibition of c-Jun phosphorylation and AP-1 activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Apoptosis regulators and responses in human melanocytic and keratinocytic cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Redox regulation in human melanocytes and melanoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

The INK4A/ARF locus and its two gene products

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

p16INK4A participates in a G1 arrest checkpoint in response to DNA damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Loss of the p16INK4a and p15INK4b genes, as well as neighboring 9p21 markers, in sporadic melanoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Mechanisms of ultraviolet light-induced pigmentation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

The inherent cytotoxicity of melanin precursors: a revision

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Oxidative stress induces protein phosphatase 2A-dependent dephosphorylation of the pocket proteins pRb, p107, and p130.

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.419

Oxidative stress impairs the repair of oxidative DNA base modifications in human skin fibroblasts and melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.419

High-risk Melanoma Susceptibility Genes and Pancreatic Cancer, Neural System Tumors, and Uveal Melanoma across GenoMEL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.419

Measurements of UV-generated free radicals/reactive oxygen species (ROS) in skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.419

Concordant loss of heterozygosity of DNA repair gene, hOGG1, in melanoma in situ and atypical melanocytic hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.419

The expression of p16(INK4a), the product of a tumor suppressor gene for melanoma, is upregulated in human melanocytes by UVB irradiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.419

Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.419

Functional impairment of melanoma-associated p16(INK4a) mutants in melanoma cells despite retention of cyclin-dependent kinase 4 binding.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003740

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

27 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.419

Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.419

Increased sensitivity to peroxidizing agents is correlated with an imbalance of antioxidants in normal melanocytes from melanoma patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.419

Oncogene activation in melanocytes links reactive oxygen to multinucleated phenotype and senescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.419

Disturbed melanin synthesis and chronic oxidative stress in dysplastic naevi

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.419

An examination of focal adhesion formation and tyrosine phosphorylation in fibroblasts isolated from src-, fyn-, and yes- mice

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20838381

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2010.419

1 reference

Dimensions Publication ID

2 August 2017

0 references

1 reference

2 August 2017

1 reference