(Q34415600)

PubMed publication ID

2 August 2017

1 reference

title

Retigabine: chemical synthesis to clinical application (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741764&resulttype=core&format=json

12 May 2020

author name string

G Blackburn-Munro

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741764&resulttype=core&format=json

12 May 2020

W Dalby-Brown

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741764&resulttype=core&format=json

12 May 2020

N R Mirza

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741764&resulttype=core&format=json

12 May 2020

J D Mikkelsen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741764&resulttype=core&format=json

12 May 2020

R E Blackburn-Munro

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741764&resulttype=core&format=json

12 May 2020

publication date

1 January 2005

1 reference

PubMed publication ID

15867950

CNS Neuroscience & Therapeutics

2 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741764&resulttype=core&format=json

12 May 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741764&resulttype=core&format=json

12 May 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741764&resulttype=core&format=json

12 May 2020

page(s)

1-20

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741764&resulttype=core&format=json

Pharmacokinetic interaction between retigabine and lamotrigine in healthy subjects

12 May 2020

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2005.TB00033.X

Changes in expression of voltage-gated potassium channels in dorsal root ganglion neurons following axotomy

21 January 2018

1 reference

12 December 2020

Retigabine N-glucuronidation and its potential role in enterohepatic circulation

1 reference

12 December 2020

Metabolism of retigabine (D-23129), a novel anticonvulsant

1 reference

12 December 2020

Characterization of the K+ channel opening effect of the anticonvulsant retigabine in PC12 cells

1 reference

12 December 2020

The molecular pathophysiology of pain: abnormal expression of sodium channel genes and its contributions to hyperexcitability of primary sensory neurons

1 reference

12 December 2020

Defensive conditioning-related functional heterogeneity among nuclei of the rat amygdala revealed by c-Fos mapping.

1 reference

12 December 2020

The anticonvulsant retigabine potently suppresses epileptiform discharges in the low Ca ++ and low Mg++ model in the hippocampal slice preparation.

1 reference

12 December 2020

Retigabine strongly reduces repetitive firing in rat entorhinal cortex

1 reference

12 December 2020

The novel anticonvulsant retigabine activates M-currents in Chinese hamster ovary-cells tranfected with human KCNQ2/3 subunits

1 reference

12 December 2020

Neuronal correlates of fear in the lateral amygdala: multiple extracellular recordings in conscious cats.

1 reference

12 December 2020

Neuronal plasticity: increasing the gain in pain

1 reference

12 December 2020

Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine

1 reference

12 December 2020

KCNQ2/KCNQ3 K+ channels and the molecular pathogenesis of epilepsy: implications for therapy

1 reference

12 December 2020

Retigabine, a novel anti-convulsant, enhances activation of KCNQ2/Q3 potassium channels

1 reference

12 December 2020

Modulation and genetic identification of the M channel

1 reference

12 December 2020

Determination of retigabine and its acetyl metabolite in biological matrices by on-line solid-phase extraction (column switching) liquid chromatography with tandem mass spectrometry.

1 reference

12 December 2020

Acoustic startle and fear-potentiated startle in rats selectively bred for fast and slow kindling rates: relation to monoamine activity.

1 reference

12 December 2020

Characterization of KCNQ5/Q3 potassium channels expressed in mammalian cells

1 reference

12 December 2020

Investigations into the mechanism of action of the new anticonvulsant retigabine. Interaction with GABAergic and glutamatergic neurotransmission and with voltage gated ion channels.

1 reference

12 December 2020

Neuronal KCNQ potassium channels: physiology and role in disease.

1 reference

12 December 2020

Influence of retigabine on the anticonvulsant activity of some antiepileptic drugs against audiogenic seizures in DBA/2 mice

1 reference

12 December 2020

Effects of retigabine on rhythmic synchronous activity of human neocortical slices

1 reference

12 December 2020

KCNQ4 channel activation by BMS-204352 and retigabine

1 reference

12 December 2020

Differential expression of genes encoding subthreshold-operating voltage-gated K+ channels in brain.

1 reference

12 December 2020

Activation of expressed KCNQ potassium currents and native neuronal M-type potassium currents by the anti-convulsant drug retigabine.

1 reference

12 December 2020

Myokymia and neonatal epilepsy caused by a mutation in the voltage sensor of the KCNQ2 K+ channel

1 reference

12 December 2020

Distinct potassium channels on pain-sensing neurons

1 reference

12 December 2020

Developmental aspects of human hepatic drug glucuronidation in young children and adults

1 reference

12 December 2020

Multiple-dose, linear, dose-proportional pharmacokinetics of retigabine in healthy volunteers

1 reference

12 December 2020

Activation of KCNQ5 channels stably expressed in HEK293 cells by BMS-204352.

1 reference

12 December 2020

Animal models of drug-resistant epilepsy

1 reference

12 December 2020

Antiepileptic drugs in psychiatry-focus on randomized controlled trial

1 reference

12 December 2020

Effects of age and sex on the disposition of retigabine

1 reference

12 December 2020

The anticonvulsant retigabine attenuates nociceptive behaviours in rat models of persistent and neuropathic pain

1 reference

12 December 2020

Fear, anger and compulsive behavior during seizure: involvement of large scale fronto-temporal neural networks.

1 reference

12 December 2020

Effect of the KCNQ potassium channel opener retigabine on single KCNQ2/3 channels expressed in CHO cells

1 reference

12 December 2020

Inhibition of the Amygdala: Key to Pathological States?

1 reference

12 December 2020

Neuroimaging Studies of Amygdala Function in Anxiety Disorders

1 reference

12 December 2020

Rodent doxapram model of panic: behavioral effects and c-Fos immunoreactivity in the amygdala

1 reference

12 December 2020

Stoichiometry of expressed KCNQ2/KCNQ3 potassium channels and subunit composition of native ganglionic M channels deduced from block by tetraethylammonium

1 reference

12 December 2020

Lack of pharmacokinetic interaction between retigabine and phenobarbitone at steady-state in healthy subjects

1 reference

12 December 2020

Localization of KCNQ5 in the normal and epileptic human temporal neocortex and hippocampal formation

1 reference

12 December 2020

KCNQ/M currents in sensory neurons: significance for pain therapy.

1 reference

12 December 2020

Analgesic efficacy of flupirtine in primary care of patients with osteoporosis related pain. A multivariate analysis

1 reference

12 December 2020

The neurobiology and control of anxious states

1 reference

12 December 2020

1 reference

12 December 2020

The emotional brain, fear, and the amygdala

1 reference

12 December 2020

Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations

1 reference

12 December 2020

Therapy discovery for pharmacoresistant epilepsy and for disease-modifying therapeutics: summary of the NIH/NINDS/AES models II workshop

1 reference

12 December 2020

International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels

1 reference

12 December 2020

KCNQ2 is a nodal K+ channel.

1 reference

12 December 2020

M-current modulators alter rat spinal nociceptive transmission: an electrophysiological study in vitro

1 reference

12 December 2020

The anti-hyperalgesic activity of retigabine is mediated by KCNQ potassium channel activation

1 reference

12 December 2020

Pharmacological characterisation of acid-induced muscle allodynia in rats

1 reference

12 December 2020

Pain-like behaviours in animals - how human are they?

1 reference

12 December 2020

The neurobiology of antiepileptic drugs

1 reference

12 December 2020

The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions.

1 reference

12 December 2020

The role of the amygdala in fear and anxiety

1 reference

12 December 2020

Evaluation of marble-burying behavior as a model of anxiety.

1 reference

12 December 2020

[Flupirtine in chronic myofacial pain conditions]

1 reference

12 December 2020

Animal models of anxiety based on classical conditioning: the conditioned emotional response (CER) and the fear-potentiated startle effect

1 reference

12 December 2020

Analgesic efficacy and safety of oral flupirtine in the treatment of cancer pain

1 reference

12 December 2020

Clinical experience with flupirtine in the U.S.

1 reference

12 December 2020

Electrophysiological characteristics of amygdaloid central nucleus neurons in the awake rabbit

1 reference

12 December 2020

A simple and reliable conflict procedure for testing anti-anxiety agents

1 reference

12 December 2020

A water lick conflict paradigm using drug experienced rats

1 reference

12 December 2020

Fear conditioning enhances short-latency auditory responses of lateral amygdala neurons: Parallel recordings in the freely behaving rat

1 reference

12 December 2020

Flupirtine. A review of its pharmacological properties, and therapeutic efficacy in pain states

1 reference

12 December 2020

The effects of anticonvulsant agents on 4-aminopyridine induced epileptiform activity in rat hippocampus in vitro

1 reference

12 December 2020

Behavioural and pharmacological characterisation of the elevated "zero-maze" as an animal model of anxiety.

1 reference

12 December 2020

[Treatment of tumor pain with flupirtine. Results of a double-blind study versus tramadol]

1 reference

12 December 2020

The effect of kindling of different nuclei in the left and right amygdala on anxiety in the rat.

1 reference

12 December 2020

Persistence of kindling: effect of partial kindling, retention interval, kindling site, and stimulation parameters

1 reference

12 December 2020

Priming of experimental anxiety by repeated subthreshold GABA blockade in the rat amygdala.

1 reference

12 December 2020

Hyperexcitability: exaggerated fear-potentiated startle produced by partial amygdala kindling.

1 reference

12 December 2020

D-23129: a new anticonvulsant with a broad spectrum activity in animal models of epileptic seizures.

1 reference

12 December 2020

D-23129: a potent anticonvulsant in the amygdala kindling model of complex partial seizures

1 reference

12 December 2020

Conditioning and ethological models of anxiety disorders: stress-in-dynamic-context anxiety models.

1 reference

12 December 2020

Persistent c-fos expression in the brains of mice with chronic social stress.

1 reference

12 December 2020

The effects of D-23129, a new experimental anticonvulsant drug, on neurotransmitter amino acids in the rat hippocampus in vitro.

1 reference

12 December 2020

1 reference

12 December 2020

[Flupirtine in comparison with chlormezanone in chronic musculoskeletal back pain. Results of a multicenter randomized double-blind study]

1 reference

12 December 2020

In vitro glucuronidation of D-23129, a new anticonvulsant, by human liver microsomes and liver slices

1 reference

12 December 2020

Excitatory amino acid receptors in the basolateral amygdala regulate anxiety responses in the social interaction test

1 reference

12 December 2020

The new anticonvulsant retigabine (D-23129) acts as an opener of K+ channels in neuronal cells

1 reference

12 December 2020

Excitatory amino acid receptor antagonists block the cardiovascular and anxiety responses elicited by gamma-aminobutyric acidA receptor blockade in the basolateral amygdala of rats.

1 reference

12 December 2020

A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns

1 reference

12 December 2020

A potassium channel mutation in neonatal human epilepsy

1 reference

12 December 2020

KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel

1 reference

12 December 2020

Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+ channels causes epilepsy

1 reference

12 December 2020

Amygdala kindling-resistant (SLOW) or -prone (FAST) rat strains show differential fear responses

1 reference

12 December 2020

Effects of retigabine (D-23129) on different patterns of epileptiform activity induced by 4-aminopyridine in rat entorhinal cortex hippocampal slices

1 reference

12 December 2020

10.1111/J.1527-3458.2005.TB00033.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741764&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741764&resulttype=core&format=json

12 May 2020

PubMed publication ID

15867950

1 reference