(Q34416102)

2 August 2017

title

L-Leucine improves the anaemia in models of Diamond Blackfan anaemia and the 5q- syndrome in a TP53-independent way (English)

1 reference

2 August 2017

Anupama Narla

1

1 reference

2 August 2017

Elspeth M Payne

2

1 reference

2 August 2017

Nirmalee Abayasekara

3

1 reference

2 August 2017

Slater N Hurst

4

1 reference

2 August 2017

David M Raiser

5

1 reference

2 August 2017

A Thomas Look

6

1 reference

2 August 2017

Nancy Berliner

7

1 reference

2 August 2017

Benjamin L Ebert

8

1 reference

2 August 2017

Arati Khanna-Gupta

9

1 reference

2 August 2017

language of work or name

English

0 references

publication date

7 August 2014

1 reference

British Journal of Haematology

2 August 2017

published in

1 reference

2 August 2017

volume

167

1 reference

2 August 2017

issue

4

1 reference

2 August 2017

page(s)

524-528

1 reference

p53-Independent cell cycle and erythroid differentiation defects in murine embryonic stem cells haploinsufficient for Diamond Blackfan anemia-proteins: RPS19 versus RPL5.

2 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211992

Loss of tumor suppressor RPL5/RPL11 does not induce cell cycle arrest but impedes proliferation due to reduced ribosome content and translation capacity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211992

Activation of the mTOR pathway by the amino acid (L)-leucine in the 5q- syndrome and other ribosomopathies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211992

L-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211992

Incidence of neoplasia in Diamond Blackfan anemia: a report from the Diamond Blackfan Anemia Registry.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211992

Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211992

Ribosomopathies: human disorders of ribosome dysfunction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211992

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211992

Successful treatment of a Diamond-Blackfan anemia patient with amino acid leucine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211992

tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211992

Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia

6 July 2018

1 reference

Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants

21 January 2018

1 reference

Ribosomal protein deficiency causes Tp53-independent erythropoiesis failure in zebrafish

21 January 2018

1 reference

Effects of L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts.

21 January 2018

1 reference

Bone Marrow Failure Syndromes: The Ribosomopathies

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25098371

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/BJH.13069

1 reference

2 August 2017

1 reference

2 August 2017

1 reference