(Q34707415)

4 August 2017

title

Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells (English)

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4 August 2017

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Shilpee Dutt

1

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4 August 2017

Anupama Narla

2

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4 August 2017

Katherine Lin

3

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4 August 2017

Ann Mullally

4

1 reference

4 August 2017

Nirmalee Abayasekara

5

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4 August 2017

Christine Megerdichian

6

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4 August 2017

Frederick H Wilson

7

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4 August 2017

Treeve Currie

8

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4 August 2017

Arati Khanna-Gupta

9

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4 August 2017

Nancy Berliner

10

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4 August 2017

Jeffery L Kutok

11

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4 August 2017

Benjamin L Ebert

12

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4 August 2017

language of work or name

English

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publication date

10 November 2010

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4 August 2017

number of pages

10

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inferred from page(s)

published in

Blood

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4 August 2017

volume

117

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4 August 2017

issue

9

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4 August 2017

page(s)

2567-2576

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Acute erythroid leukemia as defined in the World Health Organization classification is a rare and pathogenetically heterogeneous disease

4 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Deregulation of oncogene-induced senescence and p53 translational control in X-linked dyskeratosis congenita

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Ribosomopathies: human disorders of ribosome dysfunction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Genomic instability--an evolving hallmark of cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Acute erythroid leukemia: a reassessment using criteria refined in the 2008 WHO classification

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Pathogenesis of the erythroid failure in Diamond Blackfan anaemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Diamond Blackfan anemia 2008-2009: broadening the scope of ribosome biogenesis disorders

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Signaling to p53: ribosomal proteins find their way.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Tumour suppression by p53: a role for the DNA damage response?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Diamond-Blackfan anemia: diagnosis, treatment, and molecular pathogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Deletion 5q in myelodysplastic syndrome: a paradigm for the study of hemizygous deletions in cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Ribosomal dysfunction and inherited marrow failure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Putting a finger on growth surveillance: insight into MDM2 zinc finger-ribosomal protein interactions.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Distinct roles of MDMX in the regulation of p53 response to ribosomal stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Ribosomes and marrow failure: coincidental association or molecular paradigm?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Biological and prognostic significance of chromosome 5q deletions in myeloid malignancies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Inactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

The Fanconi Anemia/BRCA pathway: new faces in the crowd

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Ribosomal Protein L11 Negatively Regulates Oncoprotein MDM2 and Mediates a p53-Dependent Ribosomal-Stress Checkpoint Pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Congenital (erythroid) hypoplastic anemia. A 25-year study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Regulation of HDM2 activity by the ribosomal protein L11

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

The World Health Organization (WHO) classification of the myeloid neoplasms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

DNA microarrays identification of primary and secondary target genes regulated by p53.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

The gene encoding ribosomal protein S19 is mutated in Diamond-Blackfan anaemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Congenital hypoplastic anemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Inhibition of p73 function by Pifithrin-alpha as revealed by studies in zebrafish embryos

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062351

Induction of p53 and up-regulation of the p53 pathway in the human 5q- syndrome

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21068437

12 December 2020

inferred from PubMed ID database lookup

The onset of p53-dependent apoptosis plays a role in terminal differentiation of human normoblasts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21068437

12 December 2020

inferred from PubMed ID database lookup

A kinetic model of the erythron

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21068437

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1182/BLOOD-2010-07-295238

1 reference

4 August 2017

1 reference

4 August 2017

1 reference