(Q44362161)

2 December 2017

title

p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways. (English)

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2 December 2017

Elena A Komarova

1

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2 December 2017

Nickolay Neznanov

2

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2 December 2017

Pavel G Komarov

3

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2 December 2017

Mikhail V Chernov

4

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2 December 2017

Kaihua Wang

5

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2 December 2017

Andrei V Gudkov

6

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2 December 2017

language of work or name

English

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publication date

12 March 2003

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Journal of Biological Chemistry

2 December 2017

published in

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2 December 2017

volume

278

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2 December 2017

issue

18

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2 December 2017

page(s)

15465-15468

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Could p53 be a target for therapeutic suppression?

2 December 2017

cites work

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A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

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Chemoprotection from p53-dependent apoptosis: potential clinical applications of the p53 inhibitors

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A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

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Novel p53 inactivators with neuroprotective action: syntheses and pharmacological evaluation of 2-imino-2,3,4,5,6,7-hexahydrobenzothiazole and 2-imino-2,3,4,5,6,7-hexahydrobenzoxazole derivatives.

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p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism

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P53 mediates the apoptotic response to GTP depletion after renal ischemia-reperfusion: protective role of a p53 inhibitor

21 January 2018

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

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Poliovirus protein 3A inhibits tumor necrosis factor (TNF)-induced apoptosis by eliminating the TNF receptor from the cell surface

21 January 2018

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Functional interaction of hybrid response elements with wild-type and mutant steroid hormone receptors

21 January 2018

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Oncogenic Neu/ErbB-2 increases ets, AP-1, and NF-kappaB-dependent gene expression, and inhibiting ets activation blocks Neu-mediated cellular transformation

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Maximal stress-induced transcription from the human HSP70 promoter requires interactions with the basal promoter elements independent of rotational alignment

21 January 2018

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Roles of the heat shock transcription factors in regulation of the heat shock response and beyond

21 January 2018

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Role of the heat shock response and molecular chaperones in oncogenesis and cell death

21 January 2018

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Induction of heat shock protein 70 protects thymocytes against radiation-induced apoptosis

21 January 2018

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Nucleocytoplasmic trafficking of steroid-free glucocorticoid receptor

21 January 2018

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Nuclear hormone receptors in T lymphocytes

21 January 2018

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p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

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The regulation and roles of Rel/NF-kappa B transcription factors during lymphocyte activation

21 January 2018

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NFkappaB-dependent signaling pathways

21 January 2018

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Nuclear factor kB-independent cytoprotective pathways originating at tumor necrosis factor receptor-associated factor 2

21 January 2018

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Effects of quercetin on the heat-induced cytotoxicity of prostate cancer cells

21 January 2018

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Involvement of heat-shock protein 70 and P53 proteins in attenuation of UVC-induced apoptosis by thermal stress in hepatocellular carcinoma cells

21 January 2018

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Quercetin, apoptosis, heat shock

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.C300011200

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2 December 2017

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