(Q34417182)

2 August 2017

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title

Insulin signaling: lessons from the Drosophila tuberous sclerosis complex, a tumor suppressor (English)

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2 August 2017

0 references

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Montagne J

1

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2 August 2017

Radimerski T

series ordinal

2

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2 August 2017

Thomas G

series ordinal

3

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2 August 2017

publication date

23 October 2001

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Science's STKE : signal transduction knowledge environment

2 August 2017

published in

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2 August 2017

volume

2001

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2 August 2017

issue

105

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2 August 2017

page(s)

pe36

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Identification and validation of tumor suppressor genes

2 August 2017

cites work

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https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

The multiple roles of PTEN in tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Genetic and molecular mechanisms of cell size control

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Tuberous sclerosis complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Identification and characterization of the tuberous sclerosis gene on chromosome 16

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

The role of ARF and Rab GTPases in membrane transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Tuberous sclerosis gene 2 product modulates transcription mediated by steroid hormone receptor family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Characterization of the cytosolic tuberin-hamartin complex. Tuberin is a cytosolic chaperone for hamartin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Tuberin phosphorylation regulates its interaction with hamartin. Two proteins involved in tuberous sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Like attracts like: getting RNA processing together in the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Nucleolar size indicates the rapidity of cell proliferation in cancer tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Drosophila myc regulates cellular growth during development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Induction of ribosomal genes and hepatocyte hypertrophy by adenovirus-mediated expression of c-Myc in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

The Drosophila cyclin D-Cdk4 complex promotes cellular growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Coordination of growth and cell division in the Drosophila wing

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Hamartin and tuberin interaction with the G2/M cyclin-dependent kinase CDK1 and its regulatory cyclins A and B

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

Rescue of Cyclin D1 Deficiency by Knockin Cyclin E

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.105.PE36

10.1126/STKE.2001.105.PE36

21 January 2018

Identifiers

DOI

1 reference

2 August 2017

1 reference