(Q34421519)

2 August 2017

1 reference

title

Genetic determinants of type 2 diabetes mellitus (English)

1 reference

2 August 2017

0 references

Busch CP

1

1 reference

PubMed ID

11683767

2 August 2017

Hegele RA

series ordinal

2

1 reference

2 August 2017

1 October 2001

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2 August 2017

1 reference

2 August 2017

60

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2 August 2017

4

1 reference

2 August 2017

243-254

1 reference

Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections

2 August 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Hyperglycemia and microvascular and macrovascular disease in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

The natural history of type 2 diabetes. Implications for clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

The insulin resistance-dyslipidemic syndrome of visceral obesity: effect on patients' risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Strategies and prospects for finding insulin resistance genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Lilly Lecture 1994. The beta-cell in diabetes: from molecular genetics to clinical research

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

21 January 2018

Mutant insulin syndromes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Human type 1 diabetes and the insulin gene: principles of mapping polygenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Genetic basis of endocrine disease. 1. Molecular genetics of insulin resistant diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Glucose transporters and insulin action--implications for insulin resistance and diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

IRS proteins and beta-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Interaction between the G1057D variant of IRS-2 and overweight in the pathogenesis of type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Adrenoceptor genes in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Leptin and the regulation of body weight in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

The hormone resistin links obesity to diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Single nucleotide polymorphisms of the resistin (RSTN) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Thiazolidinediones and insulin resistance: peroxisome proliferatoractivated receptor gamma activation stimulates expression of the CAP gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Genetic, metabolic and clinical characteristics of maturity onset diabetes of the young.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Glucokinase as glucose sensor and metabolic signal generator in pancreatic beta-cells and hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Diabetes-associated mutations in a beta-cell transcription factor destabilize an antiparallel "mini-zipper" in a dimerization interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Two members of an HNF1 homeoprotein family are expressed in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Nuclear lamin A/C R482Q mutation in canadian kindreds with Dunnigan-type familial partial lipodystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Association between nuclear lamin A/C R482Q mutation and partial lipodystrophy with hyperinsulinemia, dyslipidemia, hypertension, and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Premature atherosclerosis associated with monogenic insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Maternally inherited diabetes and deafness: a new diabetes subtype

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Time of Onset of Non-Insulin-Dependent Diabetes Mellitus and Genetic Variation in the β3-Adrenergic–Receptor Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Association of a polymorphism in the beta 3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

A mutation of the b3-adrenergic receptor is associated with visceral obesity but decreased serum triglyceride

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Polymorphism of the human beta3-adrenoceptor gene forms a well-conserved haplotype that is associated with moderate obesity and altered receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Familial aggregation of obesity, candidate genes and quantitative trait loci

21 January 2018

2 references

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

21 January 2018

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

The human obesity gene map: the 1999 update.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic Caucasians: identification of a Pro12Ala PPAR gamma 2 missense mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Inhibitory effect of a proline-to-alanine substitution at codon 12 of peroxisome proliferator-activated receptor-gamma 2 on thiazolidinedione-induced adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma2 is not associated with type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Peroxisome proliferator-activated receptor gamma 2 Pro12Ala gene variant is strongly associated with larger body mass in the Taiwanese.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

The peroxisome proliferator-activated receptor gamma 2 Pro12Ala mutation is associated with early onset extreme obesity and reduced fasting glucose.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Effect of the Pro12Ala variant of the human peroxisome proliferator-activated receptor gamma 2 gene on adiposity, fat distribution, and insulin sensitivity in Japanese men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated receptor-gamma2 (PPAR-gamma2): divergent modulating effects on body mass index in obese and lean Caucasian men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

The Pro12A1a substitution in the peroxisome proliferator activated receptor gamma 2 is associated with an insulin-sensitive phenotype in families with familial combined hyperlipidemia and in nondiabetic elderly subjects with dyslipidemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associated with combined hyperlipidaemia in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Identification of nucleotide pyrophosphatase/alkaline phosphodiesterase I activity associated with the mouse plasma cell differentiation antigen PC-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Increased activity of membrane glycoprotein PC-1 in the fibroblasts from non-insulin-dependent diabetes mellitus patients with insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Decreased insulin receptor tyrosine kinase activity and plasma cell membrane glycoprotein-1 overexpression in skeletal muscle from obese women with gestational diabetes mellitus (GDM): evidence for increased serine/threonine phosphorylation in pregn

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Reversal of increased lymphocyte PC-1 activity in patients with type 2 diabetes treated with metformin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Skeletal muscle content of membrane glycoprotein PC-1 in obesity. Relationship to muscle glucose transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

A Genome Scan for Type 2 Diabetes Susceptibility Loci in a Genetically Isolated Population

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

A Gene Conferring Susceptibility to Type 2 Diabetes in Conjunction With Obesity Is Located on Chromosome 18p11

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

A common variant in PPP1R3 associated with insulin resistance and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

The 3'-untranslated region polymorphism of the gene for skeletal muscle-specific glycogen-targeting subunit of protein phosphatase 1 in the type 2 diabetic Japanese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Subcutaneous abdominal adipocyte size, a predictor of type 2 diabetes, is linked to chromosome 1q21--q23 and is associated with a common polymorphism in LMNA in Pima Indians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

The prevalence of NIDDM and associated risk factors in native Canadians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Genes and environment in type 2 diabetes and atherosclerosis in aboriginal Canadians

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

The molecular genetics of rodent single gene obesities

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Insights into insulin resistance and type 2 diabetes from knockout mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Disease model: hyperinsulinemia and insulin resistance. Part A-targeted disruption of insulin signaling or glucose transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

Pathophysiology of insulin resistance in human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

The nuclear receptor PPARgamma - bigger than fat

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Is maturity onset diabetes at young age (MODY) more common in Europe than previously assumed?

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Early-onset type-II diabetes mellitus (MODY4) linked to IPF1

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Familial partial lipodystrophy: two types of an X linked dominant syndrome, lethal in the hemizygous state

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Partial lipoatrophy with insulin resistant diabetes and hyperlipidaemia (Dunnigan syndrome).

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

The PPARgamma2 amino acid polymorphism Pro 12 Ala is prevalent in offspring of Type II diabetic patients and is associated to increased insulin sensitivity in a subgroup of obese subjects

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Variation in the gene for human peroxisome proliferator activated receptor gamma (PPARgamma) does not play a major role in the development of morbid obesity

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Genome-wide scanning for type 2 diabetes susceptibility in Canadian Oji-Cree, using 190 microsatellite markers

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

A genome-wide search for type II diabetes susceptibility genes in Chinese Hans

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Genetic variation in LMNA modulates plasma leptin and indices of obesity in aboriginal Canadians

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Reduced skeletal muscle calpain-10 transcript level is due to a cumulative decrease in major isoforms

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Absence of association of type 2 diabetes with CAPN10 and PC-1 polymorphisms in Oji-Cree

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Geographical distribution of diabetes among the native population of Canada: a national survey

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Youth-onset type 2 diabetes (Y2DM) associated with HNF1A S319 in aboriginal Canadians

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Clinical utility of HNF1A genotyping for diabetes in aboriginal Canadians

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

Disparity between association and linkage analysis for HNF1A G319S in type 2 diabetes in Canadian Oji-Cree

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.600401.X

7 January 2021

10.1034/J.1399-0004.2001.600401.X

Identifiers

DOI

1 reference

2 August 2017

1 reference

PubMed ID

11683767