(Q34427735)

2 August 2017

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title

Quantitative methods for the analysis of protein phosphorylation in drug development (English)

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2 August 2017

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D Michael Olive

1

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2 August 2017

publication date

1 October 2004

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Expert Review of Proteomics

2 August 2017

published in

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2 August 2017

volume

1

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2 August 2017

issue

3

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2 August 2017

page(s)

327-341

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Oncogenic kinase signalling

2 August 2017

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Development and application of fluorescence polarization assays in drug discovery

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Ras and Rho regulation of the cell cycle and oncogenesis

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Protein kinase C alpha activates RAF-1 by direct phosphorylation

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

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Development and validation of a competitive AKT serine/threonine kinase fluorescence polarization assay using a product-specific anti-phospho-serine antibody

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Fluorescence polarization assays for high throughput screening of G protein-coupled receptors.

21 January 2018

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An evaluation of fluorescence polarization and lifetime discriminated polarization for high throughput screening of serine/threonine kinases

21 January 2018

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Overcoming compound interference in fluorescence polarization-based kinase assays using far-red tracers

21 January 2018

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Evaluation of compound interference in immobilized metal ion affinity-based fluorescence polarization detection with a four million member compound collection

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Development of a fluorescence polarization AKT serine/threonine kinase assay using an immobilized metal ion affinity-based technology

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High-throughput screening with immobilized metal ion affinity-based fluorescence polarization detection, a homogeneous assay for protein kinases

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Development and validation of a fluorescence technology for both primary and secondary screening of kinases that facilitates compound selectivity and site-specific inhibitor determination

21 January 2018

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Applications of fluorescent polymer superquenching to high throughput screening assays for protein kinases

21 January 2018

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A microchip-based enzyme assay for protein kinase A.

21 January 2018

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Comparison of on-chip and off-chip microfluidic kinase assay formats.

21 January 2018

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Assessing cellular protein phosphorylation: high throughput drug discovery technologies

21 January 2018

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Activation and targeting of mitogen-activated protein kinases by G-protein-coupled receptors.

21 January 2018

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G protein selectivity is regulated by multiple intracellular regions of GPCRs

21 January 2018

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Tracking cell signaling protein expression and phosphorylation by innovative proteomic solutions

21 January 2018

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Noninvasive imaging of protein-protein interactions in living animals

21 January 2018

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Single-molecule imaging analysis of Ras activation in living cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/14789450.1.3.327

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2 August 2017

1 reference