(Q34428081)

2 August 2017

title

Sirt5 deacylation activities show differential sensitivities to nicotinamide inhibition (English)

1 reference

2 August 2017

1 reference

ChEBI release 2020-05-28

Benjamin Suenkel

3

0 references

Mike Schutkowski

object named as

Mike Schutkowski

5

0 references

Clemens Steegborn

6

object named as

Clemens Steegborn

1 reference

2 August 2017

Frank Fischer

1

1 reference

2 August 2017

Melanie Gertz

2

1 reference

2 August 2017

Mahadevan Lakshminarasimhan

4

1 reference

2 August 2017

language of work or name

English

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publication date

19 September 2012

1 reference

2 August 2017

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2 August 2017

volume

7

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2 August 2017

issue

9

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2 August 2017

page(s)

e45098

1 reference

Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

19 September 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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Thiosuccinyl peptides as Sirt5-specific inhibitors

6 July 2018

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Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Structure-based development of novel sirtuin inhibitors

6 July 2018

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The first identification of lysine malonylation substrates and its regulatory enzyme

6 July 2018

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Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome

6 July 2018

1 reference

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Protein-binding assays in biological liquids using microscale thermophoresis

6 July 2018

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Emerging mitochondrial signaling mechanisms in physiology, aging processes, and as drug targets

6 July 2018

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Peptide arrays identify isoform-selective substrates for profiling endogenous lysine deacetylase activity

6 July 2018

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Sirtuin chemical mechanisms

6 July 2018

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6 July 2018

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Sirtuins inhibitors: the approach to affinity and selectivity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Function and regulation of the mitochondrial sirtuin isoform Sirt5 in Mammalia

6 July 2018

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Structural basis for sirtuin function: what we know and what we don't

6 July 2018

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A continuous microplate assay for sirtuins and nicotinamide-producing enzymes

6 July 2018

1 reference

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Lysine acetylation targets protein complexes and co-regulates major cellular functions

6 July 2018

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Crystal structures of human SIRT3 displaying substrate-induced conformational changes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

6 July 2018

1 reference

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Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5

6 July 2018

1 reference

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The Sirtuin family: therapeutic targets to treat diseases of aging

6 July 2018

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6 July 2018

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Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

NAD metabolism and sirtuins: metabolic regulation of protein deacetylation in stress and toxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Sirtuins: a conserved key unlocking AceCS activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

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6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Assignment of the NAD-dependent deacetylase sirtuin 5 gene (SIRT5) to human chromosome band 6p23 by in situ hybridization.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Calorie restriction--the SIR2 connection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Substrate-specific activation of sirtuins by resveratrol

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Coot: model-building tools for molecular graphics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Enzymatic assays for NAD-dependent deacetylase activities

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Structure of a Sir2 enzyme bound to an acetylated p53 peptide

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

SIR2 family of NAD(+)-dependent protein deacetylases.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Evolutionarily conserved pathways of energetic connectivity in protein families

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

High-throughput assays for sirtuin enzymes: a microfluidic mobility shift assay and a bioluminescence assay

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446968

10.1371/JOURNAL.PONE.0045098

27 October 2018

Identifiers

DOI

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2 August 2017

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1 reference

2 August 2017

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