(Q34428366)

2 August 2017

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title

Genetics of leptin and obesity: a HuGE review (English)

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2 August 2017

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Valentina Paracchini

1

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Emanuela Taioli

series ordinal

3

object named as

Emanuela Taioli

1 reference

2 August 2017

Paola Pedotti

2

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PubMed ID

15972940

2 August 2017

language of work or name

English

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publication date

22 June 2005

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American Journal of Epidemiology

2 August 2017

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2 August 2017

162

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2 August 2017

2

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2 August 2017

101-114

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The biology of leptin: a review

2 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Leptin and its receptors: regulators of whole-body energy homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Leptin: the tale of an obesity gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Adipogenesis and obesity: rounding out the big picture

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Leptin's sexual dimorphism results from genotype by sex interactions mediated by testosterone

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Leptin levels in diabetic and nondiabetic subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Structural organization and chromosomal assignment of the human obese gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

The mouse obese gene. Genomic organization, promoter activity, and activation by CCAAT/enhancer-binding protein alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Overexpression of the obese (ob) gene in adipose tissue of human obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Identification of targets of leptin action in rat hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Identification and expression cloning of a leptin receptor, OB-R

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Cytokine receptor signal transduction and the control of hematopoietic cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Role of peroxisome proliferator-activated receptor gamma and retinoid X receptor heterodimer in hepatogastroenterological diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

The organization, promoter analysis, and expression of the human PPARgamma gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Obese, a new mutation in the house mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Positional cloning of the mouse obese gene and its human homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Congenital leptin deficiency is associated with severe early-onset obesity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

The hypothalamic leptin receptor in humans: identification of incidental sequence polymorphisms and absence of the db/db mouse and fa/fa rat mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Leptin responsiveness to energy restriction: genetic variation in the leptin receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Obesity associated with a mutation in a genetic regulator of adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic Caucasians: identification of a Pro12Ala PPAR gamma 2 missense mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Effect of the Pro12Ala polymorphism in the peroxisome proliferator-activated receptor (PPAR) gamma2 gene on the expression of PPARgamma target genes in adipose tissue of massively obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Meta-analyses of randomized controlled trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Methodologic guidelines for systematic reviews of randomized control trials in health care from the Potsdam Consultation on Meta-Analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Operating characteristics of a rank correlation test for publication bias

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Meta-analysis: formulating, evaluating, combining, and reporting

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Leptin receptor gene variation and obesity: lack of association in a white British male population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Genetic factors as predictors of weight gain in young adult Dutch men and women

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Hypertension in Obesity and the Leptin Receptor Gene Locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Amino acid variants in the human leptin receptor: lack of association to juvenile onset obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Human leptin receptor gene in obese Japanese subjects: evidence against either obesity-causing mutations or association of sequence variants with obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Estrogen receptor alpha gene polymorphisms Pvu II and Xba I influence association between leptin receptor gene polymorphism (Gln223Arg) and bone mineral density in young men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Structure and sequence variation at the human leptin receptor gene in lean and obese Pima Indians

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Exonic and intronic sequence variation in the human leptin receptor gene (LEPR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Exon 6 and 2 peroxisome proliferator-activated receptor-gamma polymorphisms in polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

A functional variant in the peroxisome proliferator-activated receptor gamma2 promoter is associated with predictors of obesity and type 2 diabetes in Pima Indians

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Lack of association of the codon 12 polymorphism of the peroxisome proliferator-activated receptor gamma gene with breast cancer and body mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Prospective study of the association between the proline to alanine codon 12 polymorphism in the PPARgamma gene and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Interaction between a peroxisome proliferator-activated receptor gene polymorphism and dietary fat intake in relation to body mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Does peroxisome proliferator-activated receptor gamma genotype (Pro12ala) modify the association of physical activity and dietary fat with fasting insulin level?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

The silent PPARgamma exon 6 CAC(His) --> CAT(His) polymorphism does not affect the plasma leptin levels in a collective of first degree relatives of type 2 diabetes patients from South West Germany

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated receptor-gamma2 (PPAR-gamma2): divergent modulating effects on body mass index in obese and lean Caucasian men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Association of the PRO12ALA polymorphism of the PPAR-gamma2 gene with oxidized low-density lipoprotein and cardiolipin autoantibodies in nondiabetic and type 2 diabetic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Variants of uncoupling protein-2 gene and obesity: interaction with peroxisome proliferator-activated receptorgamma2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma-2 gene on adiposity, insulin sensitivity and lipid profile in the Spanish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associated with combined hyperlipidaemia in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Effect of the Pro12Ala variant of the human peroxisome proliferator-activated receptor gamma 2 gene on adiposity, fat distribution, and insulin sensitivity in Japanese men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

The Pro12Ala polymorphism in PPAR gamma2 may confer resistance to type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

PPAR(gamma)2 gene Pro12Ala polymorphism may influence serum level of an adipocyte-derived protein, adiponectin, in the Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

PPARgamma gene polymorphism is associated with exercise-mediated changes of insulin resistance in healthy men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Peroxisome proliferator-activated receptor gamma 2 Pro12Ala gene variant is strongly associated with larger body mass in the Taiwanese.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Leptin and its potential role in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Evaluation of obesity. Who are the obese?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Diabetes: insulin resistance and derangements in lipid metabolism. Cure through intervention in fat transport and storage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

The obesity epidemic: pathophysiology and consequences of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Obesity: the worldwide epidemic

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Medical management of obesity in women: office-based approaches to weight management.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Leptin and prostate: implications for cancer prevention--overview of genetics and molecular interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

The epidemiology of central fat distribution in relation to disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Physical activity efficacy and effectiveness among older adults and minorities

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Impact of obesity on the risk of heart failure and survival after the onset of heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Obesity, hypertension, and vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Evidence for gene-nutrient interaction at the PPARgamma locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Polymorphisms in candidate obesity genes and their interaction with dietary intake of n-6 polyunsaturated fatty acids affect obesity risk in a sub-sample of the EPIC-Heidelberg cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

'Racial' differences in genetic effects for complex diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Effect of the peroxisome proliferator activated receptor-gamma gene Pro12Ala variant on body mass index: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

The human obesity gene map: the 2003 update

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

The human obesity gene map: the 2002 update

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

The future of obesity management

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

A genetic polymorphism of the peroxisome proliferator-activated receptor gamma gene influences plasma leptin levels in obese humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

The genetics of obesity: practical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

LEPR gene polymorphisms: associations with overweight, fat mass and response to diet in women

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Genetic Variation and Obesity in Australian Women: A Prospective Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

The Gln223Arg polymorphism of the leptin receptor in Pima Indians: influence on energy expenditure, physical activity and lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWI174

Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension

21 January 2018

1 reference

COCI

https://opencitations.net/index/coci/api/v1/citations/10.1038/47254

15 July 2023

Identifiers

DOI

10.1093/AJE/KWI174

1 reference

2 August 2017

1 reference

PubMed ID

15972940