(Q34428897)

2 August 2017

Exploiting DNA mismatch repair deficiency as a therapeutic strategy (English)

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2 August 2017

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25017099%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Sarah A Martin

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25017099%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

language of work or name

English

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publication date

11 July 2014

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Experimental Cell Research

2 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25017099%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

329

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25017099%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

110-115

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25017099%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

issue

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25017099%20AND%20SRC:MED&resulttype=core&format=json

DNA mismatch repair: molecular mechanism, cancer, and ageing

12 June 2020

cites work

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.07.004

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7 January 2021

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The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine

7 January 2021

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Oxidative stress and the DNA mismatch repair pathway

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Mismatch repair and DNA damage signalling

7 January 2021

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The DNA mismatch repair gene hMSH2 is a potent coactivator of oestrogen receptor alpha

7 January 2021

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Accurate homologous recombination is a prominent double-strand break repair pathway in mammalian chromosomes and is modulated by mismatch repair protein Msh2.

7 January 2021

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Life-time risk of different cancers in hereditary non-polyposis colorectal cancer (HNPCC) syndrome.

7 January 2021

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Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics

7 January 2021

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Mismatch repair status and outcomes after adjuvant therapy in patients with surgically staged endometrial cancer.

7 January 2021

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A study of genomic instability in early preneoplastic colonic lesions.

7 January 2021

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Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours

7 January 2021

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Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

7 January 2021

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Mismatch repair deficient colorectal cancer in the era of personalized treatment

7 January 2021

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MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance.

7 January 2021

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5-Fluorouracil: mechanisms of action and clinical strategies

7 January 2021

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Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy

7 January 2021

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Systematic review of microsatellite instability and colorectal cancer prognosis

7 January 2021

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The efficacy of adjuvant chemotherapy with 5-fluorouracil in colorectal cancer depends on the mismatch repair status.

7 January 2021

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DNA mismatch repair and the DNA damage response to ionizing radiation: making sense of apparently conflicting data

7 January 2021

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A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage.

7 January 2021

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DNA damage-induced cell death: from specific DNA lesions to the DNA damage response and apoptosis

7 January 2021

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The concept of synthetic lethality in the context of anticancer therapy

7 January 2021

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DNA polymerases as potential therapeutic targets for cancers deficient in the DNA mismatch repair proteins MSH2 or MLH1

7 January 2021

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Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2

7 January 2021

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Parallel high-throughput RNA interference screens identify PINK1 as a potential therapeutic target for the treatment of DNA mismatch repair-deficient cancers

7 January 2021

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Cytosine-based nucleoside analogs are selectively lethal to DNA mismatch repair-deficient tumour cells by enhancing levels of intracellular oxidative stress

7 January 2021

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Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines

7 January 2021

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

7 January 2021

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

7 January 2021

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MRE11 deficiency increases sensitivity to poly(ADP-ribose) polymerase inhibition in microsatellite unstable colorectal cancers

7 January 2021

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7 January 2021

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Modulation of mismatch repair and genomic stability by miR-155

7 January 2021

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The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα

7 January 2021

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Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair

7 January 2021

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7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25017099%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference