(Q34433853)

2 August 2017

A genetic mechanism for Tibetan high-altitude adaptation (English)

1 reference

2 August 2017

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Don A McClain

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Parvaiz A Koul

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Jinchuan Xing

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Andrew R. Wilson

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

20

Lynn B Jorde

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

16

Gregg L Semenza

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

2

Chad Huff

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

19

Tatum S Simonson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

23

Josef T Prchal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

8

Tana Wuren

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Felipe R Lorenzo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Benjamin Olenchock

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Sabina Swierczek

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Tsewang Tashi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Victor Gordeuk

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Ge Ri-Li

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Tahsin M Khan

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Prasenjit Guchhait

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Mohamed E Salama

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Ella Liberzon

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Peppi Koivunen

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

William G Kaelin

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

English

0 references

publication date

17 August 2014

1 reference

2 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

951-956

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/ng.3067

4 June 2020

exact match

0 references

cites work

Genomic analysis of natural selection and phenotypic variation in high-altitude Mongolians

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Metabolic insight into mechanisms of high-altitude adaptation in Tibetans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Two new mutations in the HIF2A gene associated with erythrocytosis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Methylation of AR locus does not always reflect X chromosome inactivation state

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Genetic determinants of Tibetan high-altitude adaptation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Distinct deregulation of the hypoxia inducible factor by PHD2 mutants identified in germline DNA of patients with polycythemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Isolated erythrocytosis: study of 67 patients and identification of three novel germ-line mutations in the prolyl hydroxylase domain protein 2 (PHD2) gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Crohn's disease and genetic hitchhiking at IBD5

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Hypoxia. 5. Hypoxia and hematopoiesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Maximum-likelihood estimation of recent shared ancestry (ERSA).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

EGLN1 involvement in high-altitude adaptation revealed through genetic analysis of extreme constitution types defined in Ayurveda

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Toward a more uniform sampling of human genetic diversity: a survey of worldwide populations by high-density genotyping

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Sequencing of 50 human exomes reveals adaptation to high altitude

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Genetic evidence for high-altitude adaptation in Tibet

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Identifying positive selection candidate loci for high-altitude adaptation in Andean populations.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Fine-scaled human genetic structure revealed by SNP microarrays

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Familial erythrocytosis arising from a gain-of-function mutation in the HIF2A gene of the oxygen sensing pathway.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

A novel erythrocytosis-associated PHD2 mutation suggests the location of a HIF binding groove

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Two routes to functional adaptation: Tibetan and Andean high-altitude natives

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

The length of peptide substrates has a marked effect on hydroxylation by the hypoxia-inducible factor prolyl 4-hydroxylases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

The kinetics of hematopoietic stem cells during and after hypoxia. A model analysis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Endemic polycythemia in Russia: mutation in the VHL gene.

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.3067

Characterization of the human PPARalpha promoter: identification of a functional nuclear receptor response element

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473257

Severe hypoxia enhances the formation of erythroid bursts from human cord blood cells and the maintenance of BFU-E in vitro

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25129147

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Analysis of the oxygen sensing pathway genes in familial chronic myeloproliferative neoplasms and identification of a novel EGLN1 germ-line mutation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25129147

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Characterization of the Human PPARα Promoter: Identification of a Functional Nuclear Receptor Response Element

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25129147

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.3067

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129147%20AND%20SRC:MED&resulttype=core&format=json