(Q34434004)

2 August 2017

title

Research review: Polygenic methods and their application to psychiatric traits (English)

1 reference

2 August 2017

Sang Hong Lee

2

0 references

Christel M Middeldorp

object named as

Christel M Middeldorp

6

0 references

Naomi R. Wray

object named as

Naomi R Wray

1

0 references

Frank Dudbridge

5

object named as

Frank Dudbridge

1 reference

2 August 2017

Divya Mehta

3

1 reference

2 August 2017

Anna A E Vinkhuyzen

4

1 reference

2 August 2017

language of work or name

1 reference

1 August 2014

1 reference

The Journal of Child Psychology and Psychiatry

2 August 2017

published in

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2 August 2017

volume

55

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2 August 2017

issue

10

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2 August 2017

page(s)

1068-1087

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Performance and robustness of penalized and unpenalized methods for genetic prediction of complex human disease.

2 August 2017

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Individual common variants exert weak effects on the risk for autism spectrum disorders

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Personality and bipolar disorder: dissecting state and trait associations between mood and personality

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Additive genetic variation in schizophrenia risk is shared by populations of African and European descent

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Replicating genotype-phenotype associations

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Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies

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Identifying bipolar disorder susceptibility loci in a densely affected pedigree

21 January 2018

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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

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Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

21 January 2018

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Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture

21 January 2018

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Genetic risk profiles for depression and anxiety in adult and elderly cohorts

21 January 2018

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Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis

21 January 2018

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Power and predictive accuracy of polygenic risk scores.

21 January 2018

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A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry

21 January 2018

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Research review: gene-environment interaction research in youth depression - a systematic review with recommendations for future research

21 January 2018

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Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms

21 January 2018

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The age-dependent decline of attention deficit hyperactivity disorder: a meta-analysis of follow-up studies

21 January 2018

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Pharmacogenetics and pharmacogenomics: a clinical reality.

21 January 2018

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Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster

21 January 2018

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De novo mutations in schizophrenia implicate synaptic networks

21 January 2018

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Genomic selection: prediction of accuracy and maximisation of long term response

21 January 2018

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A polygenic theory of schizophrenia

21 January 2018

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Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJCPP.12295

High loading of polygenic risk for ADHD in children with comorbid aggression

21 January 2018

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https://api.crossref.org/works/10.1111%2FJCPP.12295

Polygenic dissection of the bipolar phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Shared polygenic contribution between childhood attention-deficit hyperactivity disorder and adult schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Tandem repeat polymorphisms: modulators of disease susceptibility and candidates for 'missing heritability'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Data and theory point to mainly additive genetic variance for complex traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Individual differences in amygdala-medial prefrontal anatomy link negative affect, impaired social functioning, and polygenic depression risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Genome-wide association study of schizophrenia in a Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Rare chromosomal deletions and duplications increase risk of schizophrenia

21 January 2018

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https://api.crossref.org/works/10.1111%2FJCPP.12295

The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for GxE research

21 January 2018

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https://api.crossref.org/works/10.1111%2FJCPP.12295

Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJCPP.12295

Why has it taken so long for biological psychiatry to develop clinical tests and what to do about it?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Resemblance of psychotic symptoms and syndromes in affected sibling pairs from the Irish Study of High-Density Schizophrenia Families: evidence for possible etiologic heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Schizophrenia genetics: where next?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Common genetic variants, acting additively, are a major source of risk for autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Complement factor H polymorphism in age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Risk prediction using genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Risk of bipolar disorder and schizophrenia in relatives of people with attention-deficit hyperactivity disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

A better coefficient of determination for genetic profile analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Estimating missing heritability for disease from genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Genome-wide association study of multiplex schizophrenia pedigrees.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Parental depression and depression in offspring: evidence for familial characteristics and subtypes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Genome-wide association uncovers shared genetic effects among personality traits and mood states

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Epistasis and quantitative traits: using model organisms to study gene-gene interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Genomewide association studies and assessment of the risk of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Bringing genome-wide association findings into clinical use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Finding the missing heritability of complex diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Genetic risk for attention-deficit/hyperactivity disorder contributes to neurodevelopmental traits in the general population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Where GWAS and epidemiology meet: opportunities for the simultaneous study of genetic and environmental risk factors in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

The Heritability of Bipolar Affective Disorder and the Genetic Relationship to Unipolar Depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Genetics of rheumatoid arthritis contributes to biology and drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Meta-analysis of genome-wide association studies for panic disorder in the Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Validating therapeutic targets through human genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Commentary: missing heritability, polygenic scores, and gene-environment correlation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

PLINK: a tool set for whole-genome association and population-based linkage analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Genome-wide association study identifies five new schizophrenia loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Searching for genetic determinants in the new millennium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Use of genome-wide association studies for drug repositioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Clinical characteristics of major depressive disorder run in families--a community study of 933 mothers and their children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Whole-genome association study of bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Risk prediction of complex diseases from family history and known susceptibility loci, with applications for cancer screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Improved heritability estimation from genome-wide SNPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Common variation contributes to the genetic architecture of social communication traits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Large recurrent microdeletions associated with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Assumptions and properties of limiting pathway models for analysis of epistasis in complex traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

21 January 2018

Don't give up on GWAS.

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Family history of schizophrenia and bipolar disorder as risk factors for autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

The heritability of human disease: estimation, uses and abuses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Biological, clinical and population relevance of 95 loci for blood lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Editorial perspective: Why is there such a mismatch between traditional heritability estimates and molecular genetic findings for behavioural traits?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

No genetic influence for childhood behavior problems from DNA analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

First genome-wide association study on anxiety-related behaviours in childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Efficient methods to compute genomic predictions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Genetics of callous-unemotional behavior in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Five years of GWAS discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated samples.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Heritability in the genomics era — concepts and misconceptions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

No evidence that common genetic risk variation is shared between schizophrenia and autism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

The interplay of genes and adolescent development in substance use disorders: leveraging findings from GWAS meta-analyses to test developmental hypotheses about nicotine consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

The influence of polygenic risk for bipolar disorder on neural activation assessed using fMRI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Polygenic risk and white matter integrity in individuals at high risk of mood disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Using summary data from the danish national registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

The genetic interpretation of area under the ROC curve in genomic profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Pitfalls of predicting complex traits from SNPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Common SNPs explain a large proportion of the heritability for human height

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

GCTA: a tool for genome-wide complex trait analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: genome-wide association study of both common and rare variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Genomic inflation factors under polygenic inheritance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

Heritability in the genome-wide association era

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

The mystery of missing heritability: Genetic interactions create phantom heritability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCPP.12295

21 January 2018

Identifiers

DOI

10.1111/JCPP.12295

1 reference

2 August 2017

1 reference