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Stability and function of JC virus large T antigen and T' proteins are altered by mutation of their phosphorylated threonine 125 residues.
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Europe PubMed Central
PMC publication ID
1395387
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16474116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
title
Stability and function of JC virus large T antigen and T' proteins are altered by mutation of their phosphorylated threonine 125 residues
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
1395387
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16474116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
main subject
phosphorylation
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author
Shiva K Tyagarajan
series ordinal
1
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Europe PubMed Central
PMC publication ID
1395387
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16474116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
author name string
Richard J Frisque
series ordinal
2
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Europe PubMed Central
PMC publication ID
1395387
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16474116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
language of work or name
English
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publication date
1 March 2006
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Europe PubMed Central
PMC publication ID
1395387
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16474116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
published in
Journal of Virology
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Europe PubMed Central
PMC publication ID
1395387
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16474116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
volume
80
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Europe PubMed Central
PMC publication ID
1395387
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16474116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
issue
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
1395387
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16474116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
page(s)
2083-2091
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Europe PubMed Central
PMC publication ID
1395387
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16474116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1395387/fullTextXML
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Phosphorylation of simian virus 40 T antigen on Thr 124 selectively promotes double-hexamer formation on subfragments of the viral core origin
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Purified JC virus T and T' proteins differentially interact with the retinoblastoma family of tumor suppressor proteins
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Mutation of the cyclin-dependent kinase phosphorylation site in simian virus 40 (SV40) large T antigen specifically blocks SV40 origin DNA unwinding
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Converting the JCV T antigen Rb binding domain to that of SV40 does not alter JCV's limited transforming activity but does eliminate viral viability
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Biochemical characterization and localization of JC virus large T antigen phosphorylation domains
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Simian Virus 40 Large T Antigen Is Phosphorylated at Multiple Sites Clustered in Two Separate Regions
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Mutations in the phosphorylation sites of simian virus 40 (SV40) T antigen alter its origin DNA-binding specificity for sites I or II and affect SV40 DNA replication activity
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p34cdc2-mediated phosphorylation at T124 inhibits nuclear import of SV-40 T antigen proteins
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T antigen and initiation of cell DNA synthesis in a temperature-sensitive mouse line transformed by an SV40ts a mutant and in heterokaryons of the transformed cells and chick erythrocytes
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Identifiers
DOI
10.1128/JVI.80.5.2083-2091.2006
1 reference
stated in
Europe PubMed Central
PMC publication ID
1395387
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16474116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
PMC publication ID
1395387
1 reference
stated in
Europe PubMed Central
PMC publication ID
1395387
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16474116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
PubMed publication ID
16474116
1 reference
stated in
Europe PubMed Central
PMC publication ID
1395387
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16474116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
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