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Mechanisms of simian virus 40 T-antigen activation by phosphorylation of threonine 124
scientific article published in June 1996
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
190266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8648725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
title
Mechanisms of simian virus 40 T-antigen activation by phosphorylation of threonine 124
(English)
1 reference
stated in
Europe PubMed Central
PMCID
190266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8648725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
main subject
phosphorylation
1 reference
based on heuristic
inferred from title
SV40
object named as
simian virus 40
1 reference
based on heuristic
inferred from title
author name string
D McVey
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
190266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8648725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
B Woelker
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
190266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8648725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
P Tegtmeyer
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
190266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8648725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
language of work or name
English
0 references
publication date
1 June 1996
1 reference
stated in
Europe PubMed Central
PMCID
190266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8648725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
published in
Journal of Virology
1 reference
stated in
Europe PubMed Central
PMCID
190266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8648725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
volume
70
1 reference
stated in
Europe PubMed Central
PMCID
190266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8648725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
issue
6
1 reference
stated in
Europe PubMed Central
PMCID
190266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8648725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
page(s)
3887-3893
1 reference
stated in
Europe PubMed Central
PMCID
190266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8648725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
cites work
cdc2 phosphorylation of threonine 124 activates the origin-unwinding functions of simian virus 40 T antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Mutation of the cyclin-dependent kinase phosphorylation site in simian virus 40 (SV40) large T antigen specifically blocks SV40 origin DNA unwinding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
T-antigen kinase inhibits simian virus 40 DNA replication by phosphorylation of intact T antigen on serines 120 and 123.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
The DNA-binding domain of simian virus 40 tumor antigen has multiple functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Phosphorylation and active ATP hydrolysis are not required for SV40 T antigen hexamer formation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Different oligomeric forms of protein phosphatase 2A activate and inhibit simian virus 40 DNA replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Sequence-specific binding of simian virus 40 A protein to nonorigin and cellular DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Biochemical Activities of T-Antigen Proteins Encoded by Simian Virus 40 A Gene Deletion Mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Binding of a simian virus 40 T antigen-related protein to DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Monoclonal antibodies specific for simian virus 40 tumor antigens
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Rapid and efficient site-specific mutagenesis without phenotypic selection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Mutations in the phosphorylation sites of simian virus 40 (SV40) T antigen alter its origin DNA-binding specificity for sites I or II and affect SV40 DNA replication activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Studies on the origin-specific DNA-binding domain of simian virus 40 large T antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Consensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Initiation of simian virus 40 DNA replication in vitro: large-tumor-antigen- and origin-dependent unwinding of the template
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Regulation of SV40 DNA replication by phosphorylation of T antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Simian virus 40 (SV40) DNA replication: SV40 large T antigen unwinds DNA containing the SV40 origin of replication.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
DNA-binding region of the simian virus 40 tumor antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Simian virus 40 origin DNA-binding domain on large T antigen.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Functional interactions of the simian virus 40 core origin of replication with flanking regulatory sequences
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
T antigen and template requirements for SV40 DNA replication in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Seventeen base pairs of region I encode a novel tripartite binding signal for SV40 T antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Monomers through trimers of large tumor antigen bind in region I and monomers through tetramers bind in region II of simian virus 40 origin of replication DNA as stable structures in solution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Localized melting and structural changes in the SV40 origin of replication induced by T-antigen.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Expression of simian virus 40 T antigen in Escherichia coli: localization of T-antigen origin DNA-binding domain to within 129 amino acids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Unwinding of duplex DNA from the SV40 origin of replication by T antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Properties of the DNA-binding domain of the simian virus 40 large T antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Production of simian virus 40 large tumor antigen in bacteria: altered DNA-binding specificity and dna-replication activity of underphosphorylated large tumor antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
The zinc finger region of simian virus 40 large T antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
The finger domain of simian virus 40 large T antigen controls DNA-binding specificity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Identification of simian virus 40 T-antigen residues important for specific and nonspecific binding to DNA and for helicase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
The replication functions of SV40 T antigen are regulated by phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Mapping of helicase and helicase substrate-binding domains on simian virus 40 large T antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Four major sequence elements of simian virus 40 large T antigen coordinate its specific and nonspecific DNA binding.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Three domains in the simian virus 40 core origin orchestrate the binding, melting, and DNA helicase activities of T antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
The zinc finger region of simian virus 40 large T antigen is needed for hexamer assembly and origin melting
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Cooperative assembly of simian virus 40 T-antigen hexamers on functional halves of the replication origin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Protein phosphatase 2A dephosphorylates simian virus 40 large T antigen specifically at residues involved in regulation of DNA-binding activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Glycogen phosphorylase: control by phosphorylation and allosteric effectors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Mechanism of activation of simian virus 40 DNA replication by protein phosphatase 2A
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Structure and function of simian virus 40 large tumor antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Spacing is crucial for coordination of domain functions within the simian virus 40 core origin of replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
Simian virus 40 large T antigen: the puzzle, the pieces, and the emerging picture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
The binding site on SV40 DNA for a T antigen-related protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190266
retrieved
11 July 2018
An immunoaffinity purification procedure for SV40 large T antigen
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8648725
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
ATP-dependent assembly of double hexamers of SV40 T antigen at the viral origin of DNA replication
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8648725
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
PMCID
190266
1 reference
stated in
Europe PubMed Central
PMCID
190266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8648725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
PubMed ID
8648725
1 reference
stated in
Europe PubMed Central
PMCID
190266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8648725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
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