(Q34442517)

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Safety and efficacy of idalopirdine, a 5-HT6 receptor antagonist, in patients with moderate Alzheimer's disease (LADDER): a randomised, double-blind, placebo-controlled phase 2 trial

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

Safety and efficacy of idalopirdine, a 5-HT6 receptor antagonist, in patients with moderate Alzheimer's disease (LADDER): a randomised, double-blind, placebo-controlled phase 2 trial (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

phase II clinical trial

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Alzheimer's disease

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author name string

David Wilkinson

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Kristian Windfeld

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Eskild Colding-Jørgensen

3

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Europe PubMed Central

PubMed publication ID

2 August 2017

publication date

5 October 2014

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Europe PubMed Central

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2 August 2017

Lancet Neurology

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Europe PubMed Central

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2 August 2017

13

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Europe PubMed Central

PubMed publication ID

2 August 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

1092-1099

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Role of serotonin in Alzheimer's disease: a new therapeutic target?

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5-HT6 receptors and Alzheimer's disease

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5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease

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Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats.

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Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

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A new rating scale for Alzheimer's disease.

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Validity and reliability of the Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change. The Alzheimer's Disease Cooperative Study

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The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia

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A neuropsychological test battery for use in Alzheimer disease clinical trials.

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MMRM vs. LOCF: a comprehensive comparison based on simulation study and 25 NDA datasets

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The central role of 5-HT6 receptors in modulating brain neurochemistry

1 reference

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inferred from DOI database lookup

Double-blind, controlled phase II study of a 5-HT6 receptor antagonist, SB-742457, in Alzheimer's disease

1 reference

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SB-742457 and donepezil in Alzheimer disease: a randomized, placebo-controlled study

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Identifiers

10.1016/S1474-4422(14)70198-X

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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