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5-HT6 receptors and Alzheimer's disease
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PubMed
title
5-HT6 receptors and Alzheimer's disease
(English)
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PubMed
main subject
Alzheimer's disease
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inferred from title
author
Maria Javier Ramírez
object named as
Ramírez MJ
series ordinal
1
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language of work or name
English
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PubMed
publication date
2013
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PubMed
published in
Alzheimers Research & Therapy
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volume
5
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PubMed
issue
2
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PubMed
page(s)
15
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PubMed
cites work
Effects of 5-HT6 receptor antagonism and cholinesterase inhibition in models of cognitive impairment in the rat
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The novel cellular mechanism of human 5-HT6 receptor through an interaction with Fyn
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Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor
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The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus
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PubMed Central
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21 March 2017
Antibodies and antisense oligonucleotide for probing the distribution and putative functions of central 5-HT6 receptors
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PubMed Central
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21 March 2017
Effects of 5-HT6 antagonists, Ro-4368554 and SB-258585, in tests used for the detection of cognitive enhancement and antipsychotic-like activity
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Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study
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21 March 2017
5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease
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PubMed Central
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Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466
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21 March 2017
5-ht6 receptors
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PubMed Central
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21 March 2017
Immuno-localization of serotonin 5-HT6 receptor-like material in the rat central nervous system
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21 March 2017
A novel rat serotonin (5-HT6) receptor: molecular cloning, localization and stimulation of cAMP accumulation
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PubMed Central
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21 March 2017
Activation of the 5-HT(6) receptor attenuates long-term potentiation and facilitates GABAergic neurotransmission in rat hippocampus
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PubMed Central
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21 March 2017
Increased expression of 5-HT6 receptors in the rat dorsomedial striatum impairs instrumental learning
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PubMed Central
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21 March 2017
Lack of localization of 5-HT6 receptors on cholinergic neurons: implication of multiple neurotransmitter systems in 5-HT6 receptor-mediated acetylcholine release
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PubMed Central
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21 March 2017
Characterization of the 5-HT6 receptor coupled to Ca2+ signaling using an enabling chimeric G-protein
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PubMed Central
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21 March 2017
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs
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PubMed Central
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21 March 2017
Chemocentric informatics approach to drug discovery: identification and experimental validation of selective estrogen receptor modulators as ligands of 5-hydroxytryptamine-6 receptors and as potential cognition enhancers
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28 September 2017
Serotonin receptors of type 6 (5-HT6): what can we expect from them?
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28 September 2017
Activation of 5-HT6 receptors inhibits corticostriatal glutamatergic transmission.
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PubMed Central
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28 September 2017
ST1936 stimulates cAMP, Ca2+, ERK1/2 and Fyn kinase through a full activation of cloned human 5-HT6 receptors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
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28 September 2017
5-HT(6) receptor and cognition.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
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28 September 2017
5-HT6 receptor memory and amnesia: behavioral pharmacology--learning and memory processes
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
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28 September 2017
5-HT6 medicinal chemistry
1 reference
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PubMed Central
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28 September 2017
5-hydroxytryptamine subtype 6 receptor modulators: a patent survey
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PubMed Central
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28 September 2017
E-6801, a 5-HT6 receptor agonist, improves recognition memory by combined modulation of cholinergic and glutamatergic neurotransmission in the rat.
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PubMed Central
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28 September 2017
Neurochemical basis for symptomatic treatment of Alzheimer's disease
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PubMed Central
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28 September 2017
Physical interaction of Jab1 with human serotonin 6 G-protein-coupled receptor and their possible roles in cell survival
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PubMed Central
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28 September 2017
An update on the role of the 5-hydroxytryptamine6 receptor in cognitive function
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PubMed Central
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28 September 2017
Functional interaction between 5-HT(6) receptors and hypothalamic-pituitary-adrenal axis: cognitive implications.
1 reference
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PubMed Central
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28 September 2017
Acute onset by 5-HT(6)-receptor activation on rat brain brain-derived neurotrophic factor and activity-regulated cytoskeletal-associated protein mRNA expression
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
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28 September 2017
SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
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28 September 2017
Influence of the 5-HT6 receptor on acetylcholine release in the cortex: pharmacological characterization of 4-(2-bromo-6-pyrrolidin-1-ylpyridine-4-sulfonyl)phenylamine, a potent and selective 5-HT6 receptor antagonist
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
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28 September 2017
Memories are made of this (perhaps): a review of serotonin 5-HT(6) receptor ligands and their biological functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
retrieved
28 September 2017
Effects of the 5-HT(6) receptor antagonist Ro 04-6790 on learning consolidation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
retrieved
28 September 2017
5-HT6 receptor ligands, EMD386088 and SB258585, differentially regulate 5-HT6 receptor-independent events
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
retrieved
31 May 2018
Dimebon disappointment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
retrieved
31 May 2018
5-HT6 receptor blockade differentially affects scopolamine-induced deficits of working memory, recognition memory and aversive learning in mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
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28 November 2018
Radiosynthesis and characterization of 11C-GSK215083 as a PET radioligand for the 5-HT6 receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
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28 November 2018
Synthesis and in vivo evaluation of [O-methyl-11C] N-[3,5-dichloro-2-(methoxy)phenyl]-4-(methoxy)-3-(1-piperazinyl)benzenesulfonamide as an imaging probe for 5-HT6 receptors.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
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28 November 2018
Synthesis and structure-activity relationship of novel conformationally restricted analogues of serotonin as 5-HT6 receptor ligands.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
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28 November 2018
Two novel 5-HT6 receptor antagonists ameliorate scopolamine-induced memory deficits in the object recognition and object location tasks in Wistar rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
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28 November 2018
Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
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28 November 2018
Signalling pathways associated with 5-HT6 receptors: relevance for cognitive effects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
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28 November 2018
Time-course of 5-HT(6) receptor mRNA expression during memory consolidation and amnesia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
retrieved
28 November 2018
Procognitive 5-HT6 antagonists in the rat forced swimming test: potential therapeutic utility in mood disorders associated with Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
retrieved
28 November 2018
Involvement of an altered 5-HT -{6} receptor function in behavioral symptoms of Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
retrieved
28 November 2018
Actions of novel agonists, antagonists and antipsychotic agents at recombinant rat 5-HT6 receptors: a comparative study of coupling to G alpha s.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
retrieved
28 November 2018
Differential involvement of 5-HT(1B/1D) and 5-HT6 receptors in cognitive and non-cognitive symptoms in Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
retrieved
28 November 2018
An assessment of the effects of serotonin 6 (5-HT6) receptor antagonists in rodent models of learning
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706851
retrieved
28 November 2018
Epiminocyclohepta[b]indole analogs as 5-HT6 antagonists
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23607787
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Quantitative RT-PCR distribution of serotonin 5-HT6 receptor mRNA in the central nervous system of control or 5,7-dihydroxytryptamine-treated rats
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23607787
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Design, synthesis and pharmacological evaluation of conformationally restricted N-arylsulfonyl-3-aminoalkoxy indoles as a potential 5-HT6 receptor ligands
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23607787
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1186/ALZRT169
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1371701
Dimensions Publication ID
1078719870
1 reference
stated in
SciGraph
retrieved
9 September 2019
reference URL
https://scigraph.springernature.com/pub.10.1186/alzrt169
OpenCitations bibliographic resource ID
1371701
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1371701
PMC publication ID
3706851
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1371701
PubMed publication ID
23607787
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1371701
ResearchGate publication ID
236264885
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