(Q34111024)

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E-6801, a 5-HT6 receptor agonist, improves recognition memory by combined modulation of cholinergic and glutamatergic neurotransmission in the rat.

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31 January 2020

E-6801, a 5-HT6 receptor agonist, improves recognition memory by combined modulation of cholinergic and glutamatergic neurotransmission in the rat (English)

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31 January 2020

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31 January 2020

Javier Burgueno

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Javier Burgueño

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31 January 2020

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Ian Kendall

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31 January 2020

Helge A Slotten

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31 January 2020

Xavier Codony

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31 January 2020

Peter J Pauwels

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31 January 2020

Jose M Vela

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31 January 2020

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20 April 2010

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31 January 2020

Psychopharmacology

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31 January 2020

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31 January 2020

2-3

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31 January 2020

413-430

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31 January 2020

https://scigraph.springernature.com/pub.10.1007/s00213-010-1854-3

0 references

Investigation of stretching behaviour induced by the selective 5-HT6 receptor antagonist, Ro 04-6790, in rats.

1 reference

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21 January 2018

Deletion of the fyn-kinase gene alters sensitivity to GABAergic drugs: dependence on beta2/beta3 GABAA receptor subunits

1 reference

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21 January 2018

5-Chloro-N-(4-methoxy-3-piperazin-1-yl- phenyl)-3-methyl-2-benzothiophenesulfon- amide (SB-271046): a potent, selective, and orally bioavailable 5-HT6 receptor antagonist

1 reference

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21 January 2018

Activation of 5-HT(6) receptors facilitates attentional set shifting

1 reference

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21 January 2018

Discovery of 5-arylsulfonamido-3-(pyrrolidin-2-ylmethyl)-1H-indole derivatives as potent, selective 5-HT6 receptor agonists and antagonists

1 reference

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21 January 2018

In vivo effects of the 5-HT(6) antagonist SB-271046 on striatal and frontal cortex extracellular concentrations of noradrenaline, dopamine, 5-HT, glutamate and aspartate

1 reference

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21 January 2018

The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus

1 reference

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21 January 2018

Acute onset by 5-HT(6)-receptor activation on rat brain brain-derived neurotrophic factor and activity-regulated cytoskeletal-associated protein mRNA expression

1 reference

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21 January 2018

Pre- or post-training administration of the NMDA receptor blocker MK-801 impairs object recognition memory in rats

1 reference

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21 January 2018

A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data

1 reference

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21 January 2018

Septo-hippocampal drug interactions in post-trial memory processing.

1 reference

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21 January 2018

Chronic 5-HT6 receptor modulation by E-6837 induces hypophagia and sustained weight loss in diet-induced obese rats

1 reference

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21 January 2018

The 5-HT6 Receptor Antagonist SB-271046 Reverses Scopolamine-Disrupted Consolidation of a Passive Avoidance Task and Ameliorates Spatial Task Deficits in Aged Rats

1 reference

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21 January 2018

An update on the role of the 5-hydroxytryptamine6 receptor in cognitive function

1 reference

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21 January 2018

Behavioural and neurochemical effects of post-weaning social isolation in rodents-relevance to developmental neuropsychiatric disorders.

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21 January 2018

High throughput screening technologies for direct cyclic AMP measurement

1 reference

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21 January 2018

2-Substituted tryptamines: agents with selectivity for 5-HT(6) serotonin receptors

1 reference

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21 January 2018

Analysis of NMDA receptor mediated synaptic plasticity using gene targeting: roles of Fyn and FAK non-receptor tyrosine kinases.

1 reference

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21 January 2018

Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

1 reference

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21 January 2018

5-HT6 receptor antagonists improve performance in an attentional set shifting task in rats

1 reference

https://api.crossref.org/works/10.1007%2FS00213-010-1854-3

21 January 2018

SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models.

1 reference

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21 January 2018

Medicinal chemistry driven approaches toward novel and selective serotonin 5-HT6 receptor ligands

1 reference

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21 January 2018

Medicinal chemistry strategies to 5-HT(6) receptor ligands as potential cognitive enhancers and antiobesity agents

1 reference

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21 January 2018

The serotonin1A receptor agonist 8-OHDPAT reverses delta 9-tetrahydrocannabinol-induced impairment of spatial memory and reduction of acetylcholine release in the dorsal hippocampus in rats

1 reference

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21 January 2018

Mechanism of action of memantine

1 reference

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21 January 2018

5-HT6 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing consolidation--an effect sensitive to NMDA receptor antagonism

1 reference

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21 January 2018

A role for the 5-HT(1A), 5-HT4 and 5-HT6 receptors in learning and memory

1 reference

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21 January 2018

Impact of regional 5-HT depletion on the cognitive enhancing effects of a typical 5-ht(6) receptor antagonist, Ro 04-6790, in the Novel Object Discrimination task

1 reference

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21 January 2018

Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor

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Formulation and evaluation of metronidazole acid gel for vaginal contraception

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21 January 2018

Enhancement of place and object recognition memory in young adult and old rats by RS 67333, a partial agonist of 5-HT4 receptors

1 reference

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21 January 2018

(-)-9-Dehydrogalanthaminium bromide, a new cholinesterase inhibitor, enhances place and object recognition memory in young and old rats.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-010-1854-3

21 January 2018

Combined treatment with galanthaminium bromide, a new cholinesterase inhibitor, and RS 67333, a partial agonist of 5-HT4 receptors, enhances place and object recognition in young adult and old rats.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-010-1854-3

21 January 2018

The selective 5-HT6 receptor antagonist Ro4368554 restores memory performance in cholinergic and serotonergic models of memory deficiency in the rat.

1 reference

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21 January 2018

An assessment of the effects of serotonin 6 (5-HT6) receptor antagonists in rodent models of learning

1 reference

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21 January 2018

Pro-cognitive effects of 5-HT6 receptor antagonists in the social recognition procedure in rats: implication of the frontal cortex

1 reference

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21 January 2018

Lack of localization of 5-HT6 receptors on cholinergic neurons: implication of multiple neurotransmitter systems in 5-HT6 receptor-mediated acetylcholine release

1 reference

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21 January 2018

2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists

1 reference

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21 January 2018

PRE-084, a sigma selective PCP derivative, attenuates MK-801-induced impairment of learning in mice

1 reference

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21 January 2018

Effects of the 5-HT(6) receptor antagonist Ro 04-6790 on learning consolidation

1 reference

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The effects of the 5-HT(6) receptor agonist EMD and the 5-HT(7) receptor agonist AS19 on memory formation

1 reference

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21 January 2018

Memantine improves spatial learning in a transgenic mouse model of Alzheimer's disease.

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5-HT6 receptors: a novel target for cognitive enhancement

1 reference

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21 January 2018

BGC20-761, a novel tryptamine analog, enhances memory consolidation and reverses scopolamine-induced memory deficit in social and visuospatial memory tasks through a 5-HT6 receptor-mediated mechanism.

1 reference

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21 January 2018

Radial maze performance, open-field and elevated plus-maze behaviors in Fyn-kinase deficient mice: further evidence for increased fearfulness

1 reference

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SL65.0155, a novel 5-hydroxytryptamine(4) receptor partial agonist with potent cognition-enhancing properties

1 reference

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21 January 2018

Identification of PSD-93 as a substrate for the Src family tyrosine kinase Fyn.

1 reference

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21 January 2018

Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system--too little activation is bad, too much is even worse

1 reference

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21 January 2018

Oral administration of the 5-HT6 receptor antagonists SB-357134 and SB-399885 improves memory formation in an autoshaping learning task

1 reference

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21 January 2018

The 5-HT1A receptor and recognition memory. Possible modulation of its behavioral effects by the nitrergic system

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21 January 2018

Dissociable effects of acetylcholinesterase inhibitors and phosphodiesterase type 5 inhibitors on object recognition memory: acquisition versus consolidation

1 reference

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21 January 2018

Influence of the 5-HT6 receptor on acetylcholine release in the cortex: pharmacological characterization of 4-(2-bromo-6-pyrrolidin-1-ylpyridine-4-sulfonyl)phenylamine, a potent and selective 5-HT6 receptor antagonist

1 reference

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21 January 2018

5-HT6 receptor antagonists enhance retention of a water maze task in the rat.

1 reference

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21 January 2018

Efficacy of selective 5-HT6 receptor ligands determined by monitoring 5-HT6 receptor-mediated cAMP signaling pathways

1 reference

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21 January 2018

Whole spectrum analysis of ligand efficacy at constitutively active human wild-type and S267K 5-HT6 receptors in HEK-293F cells

1 reference

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21 January 2018

A novel rat serotonin (5-HT6) receptor: molecular cloning, localization and stimulation of cAMP accumulation

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Rolipram reverses scopolamine-induced and time-dependent memory deficits in object recognition by different mechanisms of action

1 reference

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Effect of metrifonate on extracellular brain acetylcholine and object recognition in aged rats.

1 reference

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21 January 2018

Lecozotan (SRA-333): a selective serotonin 1A receptor antagonist that enhances the stimulated release of glutamate and acetylcholine in the hippocampus and possesses cognitive-enhancing properties.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-010-1854-3

21 January 2018

Effects of the novel 5-HT(6) receptor antagonist RO4368554 in rat models for cognition and sensorimotor gating.

1 reference

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21 January 2018

Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine efflux in the hippocampus of the rat.

1 reference

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21 January 2018

Characterization of Ro 04-6790 and Ro 63-0563: potent and selective antagonists at human and rat 5-HT6 receptors

1 reference

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21 January 2018

Pharmacological profile of SB-357134: a potent, selective, brain penetrant, and orally active 5-HT(6) receptor antagonist

1 reference

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21 January 2018

Biochemical and behavioral evidence for antidepressant-like effects of 5-HT6 receptor stimulation

1 reference

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Effects of the brain-penetrant and selective 5-HT6 receptor antagonist SB-399885 in animal models of anxiety and depression.

1 reference

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21 January 2018

Competitive and noncompetitive NMDA antagonist effects in rats trained to discriminate lever-press counts.

1 reference

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21 January 2018

A role for 5-ht6 receptors in retention of spatial learning in the Morris water maze.

1 reference

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21 January 2018

Reversal of a cholinergic-induced deficit in a rodent model of recognition memory by the selective 5-HT6 receptor antagonist, Ro 04-6790.

1 reference

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21 January 2018

5-ht6 receptors

1 reference

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21 January 2018

The novel cellular mechanism of human 5-HT6 receptor through an interaction with Fyn

1 reference

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21 January 2018

Enhancement of long-term spatial memory in adult rats by the noncompetitive NMDA receptor antagonists, memantine and neramexane

1 reference

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21 January 2018

Colocalization of serotonin receptor subtypes 5-HT2A, 5-HT2C, and 5-HT6 with neuropeptides in rat striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/20405281

12 December 2020

based on heuristic

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Median raphe serotonergic innervation of medial septum/diagonal band of broca (MSDB) parvalbumin-containing neurons: possible involvement of the MSDB in the desynchronization of the hippocampal EEG.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20405281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of 5-HT6 receptors in memory formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20405281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/20405281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cannabinoids alter recognition memory in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20405281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00213-010-1854-3

1 reference

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31 January 2020

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31 January 2020

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